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HIV Vpr activates a nucleolar-specific ATR pathway to degrade the nucleolar stress sensor CCDC137

Nucleic Acids Research(2025)10.1093/nar/gkaf531Source: DataRank Database

HIV Vpr activates a nucleolar-specific ATR pathway to degrade the nucleolar stress sensor CCDC137 is a research paper published in Nucleic Acids Research (2025). On theSindex it has a DataRank of 0.

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Enrichment:Funding (9 grants)OA: goldTopics (28)IDs (PubMed, PMC)Annotations (2)

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Authors (6)

Rishi S Patel,Yennifer Delgado ORCID,Mehdi Bouhaddou ORCID,Lucie Etienne ORCID,Oliver I. Fregoso ORCID

Live enrichment

PubMed:40530693 PMC:PMC12203918

French Research Agency on HIV and Emerging Infectious Diseases ANRS/MIE

Grant: ECTZ19143

NIAID NIH HHS

Grant: R01 AI147837

NIAID NIH HHS

Grant: U54 AI170792

NIH HHS

Grant: T32AI007323

National Institutes of Health

Grant: 5R01AI147837-04

Defining the regulation of double-strand DNA break repair by HIV Vpr

National Institutes of Health

Grant: 1U54AI170792-01

HARC: HIV accessory and regulatory complexes

National Institutes of Health

Grant: 1T32AI007323-01A1

MULTIDISCIPLINARY TRAINING IN MICROBIAL PATHOGENESIS

W.M. Keck Foundation Award

UCLA-CDU Center for AIDS Research

goldLicense: cc-by-nc

publisherhttps://academic.oup.com/nar/article-pdf/53/11/gkaf531/63514866/gkaf531.pdf

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/12203918

Europe_PMChttps://europepmc.org/articles/PMC12203918

Europe_PMChttps://europepmc.org/articles/PMC12203918?pdf=render

https://doi.org/10.1101/2024.09.11.612530

Fields of Study

0301 basic medicine03 medical and health sciences

MeSH Terms

Hela CellsCell NucleolusHumansHIV-1DNA DamageNuclear ProteinsSignal Transductionvpr Gene Products, Human Immunodeficiency VirusHEK293 CellsProteolysisG2 Phase Cell Cycle CheckpointsAtaxia Telangiectasia Mutated Proteins

Keywords

Nuclear Proteinsvpr Gene Products, Human Immunodeficiency VirusAtaxia Telangiectasia Mutated ProteinsGenome Integrity, Repair and Replication[SDV] Life Sciences [q-bio]G2 Phase Cell Cycle CheckpointsHEK293 CellsProteolysisHIV-1HumansCell NucleolusDNA DamageSignal TransductionHeLa Cells

HIV Vpr activates a nucleolar-specific ATR pathway to degrade the nucleolar stress sensor CCDC137

FAIR Checklist

Authors (6)

Funding (9 grants)

Open Access

Topics

Annotations (Europe PMC)