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Cancer cells are sensitive to wild-type IDH1 inhibition under nutrient limitation

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.19.390633Source: DataRank Database

Cancer cells are sensitive to wild-type IDH1 inhibition under nutrient limitation is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2020). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (4 grants)OA: greenTopics (20)IDs (PubMed, OpenAlex)SDGs (2)

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Authors (21)

Jonathan J. Hue ORCID,Hallie J. Graor ORCID,Erin Prendergast ORCID,Vanessa Chen ORCID,Joel Cassel ORCID

Live enrichment

PubMed:21097893 OpenAlex:https://openalex.org/W3101519757

National Institutes of Health

Grant: 5P50CA150964-08

Case GI SPORE

National Institutes of Health

Grant: 1F32CA247466-01

IDH1 is a novel therapeutic target in pancreatic cancer

National Institutes of Health

Grant: 1S10OD024996-01

Leica SP8 Confocal with Hyvolution2 Deconvolution

National Institutes of Health

Grant: 5R37CA227865-07

Targeting pancreatic cancer's metabolic addiction to HuR

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2020/11/20/2020.11.19.390633.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2020.11.19.390633

repositoryhttps://doi.org/10.1101/2020.11.19.390633

https://dx.doi.org/10.1101/2020.11.19.390633

Fields of Study

Cancer, Hypoxia, and MetabolismEpigenetics and DNA MethylationChemical Reactions and Isotopes0301 basic medicine03 medical and health sciences

Keywords

Isocitrate dehydrogenaseCancer cellIDH1BiochemistryPancreatic cancerAllosteric regulationTumor microenvironmentBiologyCancerCancer researchWild typeChemistryEnzymeMutantGenetics

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Affordable and clean energy