Joel Cassel

Also affiliated with Protein Express (United States)

MedicineBiochemistry, Genetics and Molecular BiologyImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 33 papers. Top paper: “Ghost mitochondria drive metastasis through adaptive GCN2/Akt therapeutic vulnerability”.

Ghost mitochondria drive metastasis through adaptive GCN2/Akt therapeutic vulnerability

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2115624119

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0.515DataRank · unranked

30 citations

Michela Perego, Ekta Agarwal, Irene Bertolini, Yuan Wang, Aaron R. Goldman +16 more

A Novel Inhibitor of HSP70 Induces Mitochondrial Toxicity and Immune Cell Recruitment in Tumors

Cancer Research(2020)10.1158/0008-5472.can-20-0397

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0DataRank · unranked

29 citations

Jessica C. Leung, Julia I-Ju Leu, Subhasree Basu, Adi Narayana Reddy Poli, Joshua L.D. Parris +16 more

SARS-CoV-2 Envelope (E) Protein Interacts with PDZ-Domain-2 of Host Tight Junction Protein ZO1

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.22.422708

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0DataRank · unranked

29 citations

Cari A. Sagum, Isabela Batista Oliva, Elizabeth Rybakovsky, Katie DiGuilio, Jingjing Liang +6 more

Kinetics characterization of ASXL1/2-mediated allosteric regulation of BAP1 deubiquitinase

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.02.24.962464

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0DataRank · unranked

0 citations

Joel Cassel, Daniel S. McCracken, Jeremy W. Prokop, Paul R. Collop, Alexander Polo +12 more

Cancer cells are sensitive to wild-type IDH1 inhibition under nutrient limitation

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.19.390633

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0DataRank · unranked

0 citations

Jonathan J. Hue, Hallie J. Graor, Erin Prendergast, Vanessa Chen, Joel Cassel +16 more

Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth

Cancer Research(2021)10.1158/0008-5472.can-20-1847

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0DataRank · unranked

99 citations

Katherine Pniewski, Caroline Perry, Sara B. Papp, Joshua D. Shaffer, Jesse N. Velasco‐Silva +9 more

SARS-CoV-2 Envelope (E) protein interacts with PDZ-domain-2 of host tight junction protein ZO1

PLoS ONE(2021)10.1371/journal.pone.0251955

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0DataRank · unranked

88 citations

Cari A. Sagum, Isabela Batista Oliva, Elizabeth Rybakovsky, Katie DiGuilio, Jingjing Liang +6 more

The FDA-Approved Anthelmintic Pyrvinium Pamoate Inhibits Pancreatic Cancer Cells in Nutrient-Depleted Conditions by Targeting the Mitochondria

Molecular Cancer Therapeutics(2021)10.1158/1535-7163.mct-20-0652

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0DataRank · unranked

36 citations

Grace A. McCarthy, Teena Nerwal, Avinoam Nevler, James B. DuHadaway, Matthew McCoy +23 more

Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in ARID1A -Mutant Ovarian Cancers

Cancer Research(2021)10.1158/0008-5472.can-21-1545

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0DataRank · unranked

32 citations

Takeshi Fukumoto, Jianhuang Lin, Nail Fatkhudinov, Timothy Nacarelli, Andrew V. Kossenkov +6 more

Kinetic Characterization of ASXL1/2-Mediated Allosteric Regulation of the BAP1 Deubiquitinase

Molecular Cancer Research(2021)10.1158/1541-7786.mcr-20-0080

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0DataRank · unranked

4 citations

Joel Cassel, Daniel S. McCracken, Jeremy W. Prokop, Eleonora Sementino, Mitchell Cheung +14 more

Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors

Nature Cancer(2022)10.1038/s43018-022-00393-y

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0DataRank · unranked

83 citations

Joel Cassel, Farheen S. Mohammed, Mehrdad Zarei, Jonathan J. Hue, Omid Hajihassani +29 more

Targeted MDM2 Degradation Reveals a New Vulnerability for p53-Inactivated Triple-Negative Breast Cancer

Cancer Discovery(2023)10.1158/2159-8290.cd-22-1131

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0DataRank · unranked

110 citations

Ramkrishna Mitra, You‐Cai Xiao, Peter Michener, Juan Palazzo, Allen Chao +5 more

An African-Specific Variant of TP5 3 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression

Cancer Discovery(2023)10.1158/2159-8290.cd-22-1315

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0DataRank · unranked

29 citations

Jessica C. Leung, Sven A. Miller, Julia I-Ju Leu, James F. Dougherty, Nicole L. Clarke +22 more

Elevated pre-mRNA 3′ end processing activity in cancer cells renders vulnerability to inhibition of cleavage and polyadenylation

Nature Communications(2023)10.1038/s41467-023-39793-8

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0DataRank · unranked

29 citations

Luyang Wang, Qingbao Ding, Jihae Shin, Joel Cassel, Qin Liu +3 more

Synthesis and characterization of I-BET151 derivatives for use in identifying protein targets in the African trypanosome

Current Research in Chemical Biology(2023)10.1016/j.crchbi.2023.100047

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0DataRank · unranked

4 citations

Rebecca C. Blyn, Gracyn Y. Buenconsejo, Melvin Hodanu, Eric Tang, Channy Danh +5 more

Thorectidiol A Isolated from the Marine Sponge Dactylospongia elegans Disrupts Interactions of the SARS-CoV-2 Spike Receptor Binding Domain with the Host ACE2 Receptor

Journal of Natural Products(2023)10.1021/acs.jnatprod.2c01030

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0DataRank · unranked

7 citations

Joel Cassel, Jinlin Zhu, Jian-Xiong Yang, Nicole J. de Voogd, Teatulohi Matainaho +6 more

A high-throughput screening assay for silencing established HIV-1 macrophage infection identifies nucleoside analogs that perturb H3K9me3 on proviral genomes

Journal of Virology(2023)10.1128/jvi.00653-23

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0DataRank · unranked

4 citations

Urvi Zankharia, Joel Cassel, Fang Lü, Joseph M. Salvino, Paul M. Lieberman +2 more

Data from Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth

(2023)10.1158/0008-5472.c.6512743.v1

N/A

0DataRank · unranked

0 citations

Katherine Pniewski, Caroline E. Perry, Sara B. Papp, Joshua D. Shaffer, Jesse N. Velasco‐Silva +9 more

Data from Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in ARID1A-Mutant Ovarian Cancers

(2023)10.1158/0008-5472.c.6513601.v1

N/A

0DataRank · unranked

0 citations

Takeshi Fukumoto, Jianhuang Lin, Nail Fatkhudinov, Timothy Nacarelli, Andrew V. Kossenkov +6 more

Data from An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression

(2023)10.1158/2159-8290.c.6700223

N/A

0DataRank · unranked

0 citations

Jessica C. Leung, Sven A. Miller, Julia I-Ju Leu, James F. Dougherty, Nicole L. Clarke +22 more

Data from An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression

(2023)10.1158/2159-8290.c.6700223.v2

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0DataRank · unranked

0 citations

Jessica C. Leung, Sven A. Miller, Julia I-Ju Leu, James F. Dougherty, Nicole L. Clarke +22 more

ACSS1-dependent acetate utilization rewires mitochondrial metabolism to support AML and melanoma tumor growth and metastasis

Cell Reports(2024)10.1016/j.celrep.2024.114988

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0DataRank · unranked

25 citations

Kelsey Salcido, Katherine Pniewski, Dzmitry Mukha, Weili Ma, Toshitha Kannan +8 more

Design of novel and highly selective SARS-CoV-2 main protease inhibitors

Antimicrobial Agents and Chemotherapy(2024)10.1128/aac.00562-24

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0DataRank · unranked

7 citations

Ian Tietjen, Nitesh Kumar Nandwana, Joel Cassel, Troy E. Messick, Emery T. Register +9 more

A Tandem-Affinity Purification Method for Identification of Primary Intracellular Drug-Binding Proteins

ACS Chemical Biology(2024)10.1021/acschembio.3c00570

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0DataRank · unranked

4 citations

Jitendra Gour, Thomas Beer, Hsin‐Yao Tang, Joel Cassel, Joseph M. Salvino +2 more

A homogeneous time-resolved fluorescence screen to identify SIRT2 deacetylase and defatty-acylase inhibitors

PLoS ONE(2024)10.1371/journal.pone.0305000

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0DataRank · unranked

1 citations

Joel Cassel, Brian C. Boyle, Daniel Oppong, Young‐Hoon Ahn, Brian P. Weiser +1 more

Targeting LxCxE cleft pocket of retinoblastoma protein in M2 macrophages inhibits ovarian cancer progression

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.05.10.593562

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0DataRank · unranked

2 citations

Taekyoung Kwak, Xue Yang, Adi Narayana Reddy Poli, Colin Hart, Avishek Bhuniya +21 more

Cloning and Functional Characterization of Novel Human Neutralizing Anti–IFN-α and Anti–IFN-β Antibodies

The Journal of Immunology(2024)10.4049/jimmunol.2400265

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0DataRank · unranked

0 citations

Lily Lu, Matthew Fair, Isabela Batista Oliva, Joel Cassel, Sonali Majumdar +7 more

Targeting Interactions Between Siglec-10 and α3β1 Integrin Enhances Macrophage-Mediated Phagocytosis of Pancreatic Cancer

Cancer Research(2025)10.1158/0008-5472.can-25-0977

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0DataRank · unranked

8 citations

Gauri Mirji, Sidra Islam, Lacy M. Simons, Smita Bhat, Amanda Pires Bonfanti +10 more

Molecular glues that inhibit deubiquitylase activity and inflammatory signaling

Nature Structural & Molecular Biology(2025)10.1038/s41594-025-01517-5

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0DataRank · unranked

8 citations

Poli Adi Narayana Reddy, Smita Bhutda, Rebecca L. Ross, Arindam Datta, Miriam Walden +19 more

Aromatic microbial metabolite hippuric acid enhances inflammatory responses in macrophages via TLR-MyD88 signaling and lipid remodeling

Cell Reports(2025)10.1016/j.celrep.2025.116749

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0DataRank · unranked

4 citations

Sajad A. Bhat, Mohamed El Sayed, Sarah Kim Reiser, Siva Pushpa Gavara, Ying Ye +10 more

Targeting LxCxE Cleft Pocket of Retinoblastoma Protein in Immunosuppressive Macrophages Inhibits Ovarian Cancer Progression

Cancer Immunology Research(2025)10.1158/2326-6066.cir-24-0440

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0DataRank · unranked

1 citations

Taekyoung Kwak, Xue Yang, Adi Narayana Reddy Poli, Colin Hart, Avishek Bhuniya +22 more

RETRACTED ARTICLE: IspH inhibitors kill Gram-negative bacteria and mobilize immune clearance

Nature(2020)10.1038/s41586-020-03074-x

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0DataRank · unranked

55 citations

Rishabh Sharma, Poli Adi Narayana Reddy, Prashanthi Vonteddu, Madeline Good, Anjana Sundarrajan +13 more

Targeting Siglec-10/α3β1 Integrin Interactions Enhances Macrophage-Mediated Phagocytosis of Pancreatic Cancer

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.06.652455

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0DataRank · unranked

3 citations

Gauri Mirji, S M Shamsul Islam, Lacy M. Simons, Sajad Ahmad Bhat, Amanda P. Bonfanti +10 more