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Non-canonical H3K79me2-dependent pathways promote the survival of MLL-rearranged leukemia

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.04.411215Source: DataRank Database

Non-canonical H3K79me2-dependent pathways promote the survival of MLL-rearranged leukemia is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2020). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (2 grants)OA: greenTopics (45)IDs (PubMed, OpenAlex)SDGs (1)

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Authors (3)

Rohan N. Shah ORCID,Alexander J. Ruthenburg ORCID,William F. Richter ORCID

Live enrichment

PubMed:19910364 OpenAlex:https://openalex.org/W3108074576

National Institutes of Health

Grant: 3R01GM115945-04S1

Quantitatively probing intra-nucleosomal chromatin variation and function

National Institutes of Health

Grant: 5T32GM007183-43

Molecular and Cellular Biology Training

greenLicense: cc-by

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2020/12/04/2020.12.04.411215.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2020.12.04.411215

repositoryhttps://doi.org/10.1101/2020.12.04.411215

repositoryhttps://doi.org/10.6082/rz714-0wj72

Fields of Study

Acute Myeloid Leukemia ResearchProtein Degradation and InhibitorsEpigenetics and DNA Methylation0301 basic medicine03 medical and health sciences0303 health sciences

Keywords

Downregulation and upregulationBiologyLeukemiaH3K4me3Context (archaeology)Cancer researchCell biologyGeneticsGeneGene expressionPromoterH3K79me2QH301-705.5Science610MV4;11MLL-rearrangedMethylationHistonesSTAT5 Transcription FactorHumansBiology (General)Enzyme InhibitorsMyeloid Ecotropic Viral Integration Site 1 ProteinFLT3Cancer BiologyGene RearrangementHomeodomain ProteinsGene Expression Regulation, LeukemicTumor Suppressor ProteinsQMV4RHistone-Lysine N-Methyltransferase11fms-Like Tyrosine Kinase 3MedicinechromatinMyeloid-Lymphoid Leukemia Protein

Sustainable Development Goals

SDG 0: Good health and well-being