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TMPRSS2 inhibitor discovery facilitated through an in silico and biochemical screening platform

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.22.436465Source: DataRank Database

TMPRSS2 inhibitor discovery facilitated through an in silico and biochemical screening platform is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2021). On theSindex it has a DataRank of 0. It has been cited 12 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access12 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (5 grants)OA: greenTopics (27)IDs (PubMed, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Julie M. Garlick ORCID,Yujin Wu ORCID,Matthew B. Soellner ORCID,Charles L. Brooks ORCID,Anna K. Mapp ORCID

Live enrichment

PubMed:33791707 OpenAlex:https://openalex.org/W3137583134

National Institutes of Health

Grant: 5R01GM103695-11

CHARMM Development for Performance, Big-Data Accessibility and Usability

National Institutes of Health

Grant: 2R35GM130587-06

Theory and Modeling of Biomolecules and their Interactions

NIGMS NIH HHS

Grant: R01 GM103695

NIGMS NIH HHS

Grant: R35 GM130587

NIH HHS

Grant: S10 OD034346

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2021/03/27/2021.03.22.436465.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2021.03.22.436465

repositoryhttps://doi.org/10.1101/2021.03.22.436465

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33791707

Fields of Study

vaccines and immunoinformatics approachesClick Chemistry and ApplicationsProtein Degradation and Inhibitors0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

Virtual screeningTMPRSS2In silicoSerine proteaseProteaseDrug discoveryComputational biologyTransmembrane proteinProtease inhibitor (pharmacology)Recombinant DNABiologyChemistryVirologyEnzymeBiochemistryCoronavirus disease 2019 (COVID-19)VirusMedicineViral loadGeneArticle

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being