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Integrative analysis of metabolite GWAS illuminates the molecular basis of pleiotropy and genetic correlation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.02.486791Source: DataRank Database

Integrative analysis of metabolite GWAS illuminates the molecular basis of pleiotropy and genetic correlation is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2022). On theSindex it has a DataRank of 0. It has been cited 8 times.

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Enrichment:Funding (3 grants)OA: greenTopics (34)Linked Datasets (3)DataCite Reuse (3)IDs (PubMed, OpenAlex)

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Authors (7)

Nicholas A. Sinnott-Armstrong ORCID,Anna Cichońska ORCID,Heli Julkunen ORCID,Eric B. Fauman ORCID,Peter Würtz ORCID

Live enrichment

PubMed:19767382 OpenAlex:https://openalex.org/W4223926476

National Institutes of Health

Grant: 1R01AG066490-01

Mapping Molecular and Phenotypic Interactions in Alzheimers Disease

Wellcome Trust

Grant: unidentified

unidentified

National Institutes of Health

Grant: 5R01HG011432-03

New methods for constructing and evaluating polygenic scores

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2022/04/04/2022.04.02.486791.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2022.04.02.486791

repositoryhttps://doi.org/10.1101/2022.04.02.486791

https://doi.org/10.7554/elife.79348

Fields of Study

Metabolomics and Mass Spectrometry StudiesGenetic Associations and EpidemiologyBioinformatics and Genomic Networks0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

PleiotropyGenome-wide association studyMetabolomicsBiologyComputational biologyContext (archaeology)MetabolomeMendelian randomizationGeneticsGeneBioinformaticsPhenotypeGenetic variantsSingle-nucleotide polymorphismQH301-705.5ScienceQRGenetics and GenomicsGenetic PleiotropyKetonesgenetic architecturePolymorphism, Single NucleotideGWASMedicineBiology (General)Amino Acidsmetabolites

Pleiotropy of UK Biobank metabolites

10.5061/dryad.79cnp5hxsDryad

Pleiotropy of UK Biobank metabolites

10.5281/zenodo.6480199Zenodo

Pleiotropy of UK Biobank metabolites

10.5281/zenodo.6480200Zenodo