Nicholas A. Sinnott-Armstrong

Also affiliated with Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa, University of Helsinki, University of Washington, Fred Hutch Cancer Center, Institute for Molecular Medicine Finland, Brotman Baty Institute, Synthetic Biologics (United States)

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

11.8Author DataRank

Indexed papers

6in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 6 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Pan-cancer analysis of whole genomes

Nature(2020)10.1038/s41586-020-1969-6

Top 3%

5.9DataRank

Top 3%3307 citations

Lauri A. Aaltonen, Federico Abascal, Adam Abeshouse, Hiroyuki Aburatani, David J. Adams +1244 more

Papers

Driven by 48 papers — median percentile 90. Top paper: “Super-resolution chromatin tracing reveals domains and cooperative interactions in single cells”.

Super-resolution chromatin tracing reveals domains and cooperative interactions in single cells

Science(2018)10.1126/science.aau1783

N/A

10.1DataRank · unranked

1078 citations

Leslie J. Mateo, Jun-Han Su, Nicholas A. Sinnott-Armstrong, Mirae Baichoo, Seon Kinrot +4 more

Large-scale genome-wide association study of coronary artery disease in genetically diverse populations

Nature Medicine(2022)10.1038/s41591-022-01891-3

N/A

6.8DataRank · unranked

363 citations

Xiang Zhu, Austin T. Hilliard, Shoa L. Clarke, Valerio Napolioni, Shining Ma +78 more

Pan-cancer analysis of whole genomes

Nature(2020)10.1038/s41586-020-1969-6

Top 3%

5.9DataRank

Top 3%3307 citations

Lauri A. Aaltonen, Federico Abascal, Adam Abeshouse, Hiroyuki Aburatani, David J. Adams +1244 more

Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

Nature(2020)10.1038/s41586-020-1965-x

Top 5%

4.6DataRank

Top 5%668 citations

Federico Abascal, Jeremiah A. Wala, Ofer Shapira, Grace Tiao, Henrik Hornshøj +1240 more

Sex-specific genetic effects across biomarkers

European Journal of Human Genetics(2020)10.1038/s41431-020-00712-w

N/A

2.7DataRank · unranked

108 citations

Yosuke Tanigawa, Fátima Rodríguez, Russ B. Altman, Nicholas A. Sinnott-Armstrong, Manuel A. Rivas +1 more

Discovery and characterization of coding and non-coding driver mutations in more than 2,500 whole cancer genomes

bioRxiv (Cold Spring Harbor Laboratory)(2017)10.1101/237313

N/A

1.7DataRank · unranked

47 citations

B. F. Francis Ouellette, Federico Abascal, Grace Tiao, Henrik Hornshøj, Nobuyoshi Hiraoka +64 more

Tracing DNA paths and RNA profiles in cultured cells and tissues with ORCA

Nature Protocols(2021)10.1038/s41596-020-00478-x

N/A

1.7DataRank · unranked

79 citations

Nicholas A. Sinnott-Armstrong, Alistair N. Boettiger, Leslie J. Mateo

Integrative analysis of metabolite GWAS illuminates the molecular basis of pleiotropy and genetic correlation

eLife(2022)10.7554/elife.79348

Top 15%

1.3DataRank

Top 15%45 citations

Nicholas A. Sinnott-Armstrong, Anna Cichońska, Heli Julkunen, Eric B. Fauman, Peter Würtz +2 more

Genetics of 35 blood and urine biomarkers in the UK Biobank

Nature Genetics(2021)10.1038/s41588-020-00757-z

N/A

1.0DataRank · unranked

806 citations

Yosuke Tanigawa, David Amar, Nina Mars, Christian Benner, Matthew Aguirre +19 more

Graphical analysis for phenome-wide causal discovery in genotyped population-scale biobanks

Nature Communications(2021)10.1038/s41467-020-20516-2

N/A

0.870DataRank · unranked

24 citations

Nicholas A. Sinnott-Armstrong, Euan A. Ashley, Manuel A. Rivas, David Amar

Chromatin accessibility dynamics in a model of human forebrain development

Science(2020)10.1126/science.aay1645

N/A

0.843DataRank · unranked

274 citations

Nicholas A. Sinnott-Armstrong, Jimena Andersen, Se‐Jin Yoon, Nina Huber, Jonathan K. Pritchard +4 more

p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR)

Cell(2021)10.1016/j.cell.2020.12.025

N/A

0.774DataRank · unranked

173 citations

Zohar Shipony, Rodrigo Lopez-Gonzalez, Lisa Nakayama, Yong‐Jie Zhang, Julien Couthouis +22 more

Multi-faceted epigenetic dysregulation of gene expression promotes esophageal squamous cell carcinoma

Nature Communications(2020)10.1038/s41467-020-17227-z

N/A

0.765DataRank · unranked

163 citations

Hayan Lee, Wei Wu, Aubhishek Zaman, S. McCorkle, Ming Yan +25 more

Author Correction: Genetics of 35 blood and urine biomarkers in the UK Biobank

Nature Genetics(2021)10.1038/s41588-021-00956-2

N/A

0.693DataRank · unranked

14 citations

Yosuke Tanigawa, David Amar, Nina Mars, Christian Benner, Matthew Aguirre +19 more

Systematic discovery and perturbation of regulatory genes in human T cells reveals the architecture of immune networks

Nature Genetics(2022)10.1038/s41588-022-01106-y

N/A

0.673DataRank · unranked

88 citations

Oren Shaked, Sahin Naqvi, Nicholas A. Sinnott-Armstrong, Arwa S. Kathiria, Christian M. Garrido +6 more

Genetic interactions drive heterogeneity in causal variant effect sizes for gene expression and complex traits

The American Journal of Human Genetics(2022)10.1016/j.ajhg.2022.05.014

N/A

0.663DataRank · unranked

82 citations

Shaila Musharoff, Jeffrey P. Spence, Harold Pimentel, Catherine Tcheandjieu, Hakhamanesh Mostafavi +19 more

Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy

Nature Communications(2023)10.1038/s41467-023-36120-z

N/A

0.621DataRank · unranked

62 citations

Eilon Sharon, Ling Lin, Nicholas A. Sinnott-Armstrong, Aditya Ambati, Selina Yogeshwar +95 more

Metabolomic epidemiology offers insights into disease aetiology

Nature Metabolism(2023)10.1038/s42255-023-00903-x

N/A

0.609DataRank · unranked

57 citations

Yiwen Zhu, Jayna Nicholas, Haley Chatelaine, Emily Drzymalla, Afrand K. Sarvestani +9 more

A flexible modeling and inference framework for estimating variant effect sizes from GWAS summary statistics

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.18.488696

N/A

0.564DataRank · unranked

42 citations

Nicholas A. Sinnott-Armstrong, Themistocles L. Assimes, Jonathan K. Pritchard, Jeffrey P. Spence

A large-scale multi-ethnic genome-wide association study of coronary artery disease

Research Square(2021)10.21203/rs.3.rs-275591/v1

N/A

0.561DataRank · unranked

11 citations

Catherine Tcheandjieu, Xiang Zhu, Austin T. Hilliard, Shoa L. Clarke, Valerio Napolioni +77 more

Discovering cellular programs of intrinsic and extrinsic drivers of metabolic traits using LipocyteProfiler

Cell Genomics(2023)10.1016/j.xgen.2023.100346

N/A

0.557DataRank · unranked

40 citations

Sophie Strobel, Josep M. Mercader, Hesam Dashti, Felipe R. C. dos Santos, Phil Kubitz +31 more

Diversity of ribosomes at the level of rRNA variation associated with human health and disease

Cell Genomics(2024)10.1016/j.xgen.2024.100629

N/A

0.550DataRank · unranked

38 citations

Teodorus Theo Susanto, Xin Sui, Jeffrey P. Spence, Ramya Rangan, Naomi R. Genuth +5 more

Genome-wide association study of long COVID

Nature Genetics(2025)10.1038/s41588-025-02100-w

N/A

0.550DataRank · unranked

38 citations

Tomoko Nakanishi, Samuel E. Jones, Shea J. Andrews, Juha Karjalainen, Beatriz Cortés +95 more

A non-coding variant linked to metabolic obesity with normal weight affects actin remodelling in subcutaneous adipocytes

Nature Metabolism(2023)10.1038/s42255-023-00807-w

N/A

0.546DataRank · unranked

37 citations

Samantha Laber, Nicholas A. Sinnott-Armstrong, Débora R. Sobreira, Sophie Strobel, Thiago M. Batista +21 more

Systematic discovery and perturbation of regulatory genes in human T cells reveals the architecture of immune networks

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.18.440363

N/A

0.510DataRank · unranked

29 citations

Oren Shaked, Sahin Naqvi, Nicholas A. Sinnott-Armstrong, Arwa S. Kathiria, Amy F. Chen +5 more

GWAS of three molecular traits highlights core genes and pathways alongside a highly polygenic background

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.20.051631

N/A

0.483DataRank · unranked

24 citations

Sahin Naqvi, Manuel A. Rivas, Jonathan K. Pritchard, Nicholas A. Sinnott-Armstrong

An epidemiological introduction to human metabolomic investigations

Trends in Endocrinology and Metabolism(2023)10.1016/j.tem.2023.06.006

N/A

0.470DataRank · unranked

22 citations

Ali Rahnavard, Priyadarshini Kachroo, Kevin Mendez, Wayne R. Lawrence, Sachelly Julián‐Serrano +8 more

Nightmares share genetic risk factors with sleep and psychiatric traits

Translational Psychiatry(2024)10.1038/s41398-023-02637-6

N/A

0.442DataRank · unranked

18 citations

Nicholas A. Sinnott-Armstrong, Katri Kantojärvi, Martin Broberg, Teemu Palviainen, Samuel E. Jones +13 more

Discovering cellular programs of intrinsic and extrinsic drivers of metabolic traits using LipocyteProfiler

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.17.452050

N/A

0.416DataRank · unranked

15 citations

Sophie Strobel, Josep M. Mercader, Hesam Dashti, Alina Ainbinder, Julius Honecker +27 more

Understanding genetic variants in context

eLife(2024)10.7554/elife.88231

N/A

0.403DataRank · unranked

10 citations

Stanley Fields, Frederick P. Roth, Lea M. Starita, Cole Trapnell, Judit Villén +3 more

Genetic and functional analysis of Raynaud’s syndrome implicates loci in vasculature and immunity

Cell Genomics(2024)10.1016/j.xgen.2024.100630

N/A

0.269DataRank · unranked

5 citations

Markus Ramste, Erik Abner, Paul Cheng, Jacqueline M. Lane, Matthew Maher +24 more

Author Correction: Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

Communications Biology(2022)10.1038/s42003-022-03769-z

N/A

0.165DataRank · unranked

2 citations

Lars Feuerbach, Chen Hong, David Mas-Ponte, Randi Istrup Pedersen, PCAWG Drivers and Functional Interpretation Group +1255 more

Social Factors of Health Covary with Population Stratification and Confound Heritability Estimates

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.12.659317

N/A

0.104DataRank · unranked

1 citations

Oona Risse‐Adams, Rangarajan Bharadwaj, Dylan Ong, Nicholas A. Sinnott-Armstrong, Shaila Musharoff +1 more

The genetic architecture of fibromyalgia across 2.5 million individuals

medRxiv(2025)10.1101/2025.09.18.25335914

N/A

0.104DataRank · unranked

1 citations

Gyða Björnsdóttir, Keon Arbabi, Lea Urpa, Hele Haapaniemi, Gudmar Thorleifsson +46 more

Addressing 6 challenges in generative AI for digital health: A scoping review

PLOS Digital Health(2024)10.1371/journal.pdig.0000503

N/A

0DataRank · unranked

96 citations

Monika W. Perez, Sean Sylvia, Jeffrey T. Leek, Nicholas A. Sinnott-Armstrong, Tara Templin

A conserved YAP/Notch/REST network controls the neuroendocrine cell fate in the lungs

Nature Communications(2022)10.1038/s41467-022-30416-2

N/A

0DataRank · unranked

78 citations

Alexandros P. Drainas, Nancy Yanzhe Li, Sarah M. Pearsall, Derrick Morgan, Nicholas A. Sinnott-Armstrong +8 more

A MicroRNA Linking Human Positive Selection and Metabolic Disorders

Cell(2020)10.1016/j.cell.2020.09.017

N/A

0DataRank · unranked

79 citations

Nicholas A. Sinnott-Armstrong, Alexandre Wagschal, Abigail R. Wark, João Paulo Camporez, Rachel J. Perry +27 more

Convergent mutations in tissue-specific regulatory regions reveal novel cancer drivers

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.21.239954

N/A

0DataRank · unranked

0 citations

José A. Seoane, Richard Sallari, Jonathan K. Pritchard, Christina Curtis, Michael P. Snyder +1 more

Integrative analysis of metabolite GWAS illuminates the molecular basis of pleiotropy and genetic correlation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.02.486791

N/A

0DataRank · unranked

8 citations

Nicholas A. Sinnott-Armstrong, Anna Cichońska, Heli Julkunen, Eric B. Fauman, Peter Würtz +2 more

Large-scale genome-wide association study of coronary artery disease in genetically diverse populations

UNC Libraries(2024)10.17615/8zyz-p282

Top 100%

0DataRank

Top 100%0 citations

Shining Ma, J.C. Bis, Noah L. Tsao, Philip S. Tsao, Yi‐Lwun Ho +81 more

Addressing 6 challenges in generative AI for digital health: A scoping review

UNC Libraries(2024)10.17615/ktkm-2151

N/A

0DataRank · unranked

0 citations

Monika W. Perez, Nicholas A. Sinnott-Armstrong, Tara Templin, Jeffrey T. Leek, Sean Sylvia

Metabolomic epidemiology offers insights into disease aetiology

UNC Libraries(2024)10.17615/yv8q-st34

N/A

0DataRank · unranked

0 citations

Burcu F. Darst, Sachelly Julián‐Serrano, Afrand K. Sarvestani, Emily Drzymalla, Katherine H. Shutta +9 more

Author Correction: Combined burden and functional impact tests for cancer driver discovery using DriverPower

Nature Communications(2022)10.1038/s41467-022-32343-8

N/A

0DataRank · unranked

0 citations

PCAWG Drivers and Functional Interpretation Working Group, Federico Abascal, Samirkumar B. Amin, Pratiti Bandopadhayay, Rameen Beroukhim +1242 more

Initial findings from the DecodeME genome-wide association study of myalgic encephalomyelitis/chronic fatigue syndrome

medRxiv(2025)10.1101/2025.08.06.25333109

N/A

0DataRank · unranked

4 citations

Thibaud Boutin, Andrew D. Bretherick, Joshua J Dibble, Esther Oluwada Ewaoluwagbemiga, Emma Northwood +56 more

Landscape of cohesin-mediated chromatin loops in the human genome

Nature(2020)10.1038/s41586-020-2151-x

N/A

0DataRank · unranked

238 citations

Rohith Srivas, Damek V. Spacek, Maya Kasowski, Mariana Ruiz-Velasco, Nicholas A. Sinnott-Armstrong +13 more

Diversity of ribosomes at the level of rRNA variation associated with human health and disease

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.30.526360

N/A

0DataRank · unranked

13 citations

Teodorus Theo Susanto, Xin Sui, Jeffrey P. Spence, Ramya Rangan, Naomi R. Genuth +5 more

Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5

Science(2021)10.1126/science.abf1008

N/A

0DataRank · unranked

118 citations

Amelia C. Joslin, Qi Zhang, Iain Williamson, Grace Hansen, Kathryn Farris +13 more

SIRPα controls CD47-dependent platelet clearance in mice and humans

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.09.570874

N/A

0DataRank · unranked

1 citations

Ying Ying Yiu, Paige S. Hansen, Aanya Subramaniam, Martin Broberg, Eric J. Gars +8 more

Nicholas A. Sinnott-Armstrong

Indexed papers

Top data-sharing exemplar

Papers