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Multi-modal Proteomic Characterization of Lysosomal Function and Proteostasis in Progranulin-Deficient Neurons

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.24.529955Source: DataRank Database

Multi-modal Proteomic Characterization of Lysosomal Function and Proteostasis in Progranulin-Deficient Neurons is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2023). On theSindex it has a DataRank of 0. It has been cited 9 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access9 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)OA: greenTopics (36)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Michael S. Fernandopulle ORCID,Stewart W. Humble ORCID,Ashley M. Frankenfield ORCID,Haorong Li ORCID,Ryan Prestil ORCID

Live enrichment

PubMed:36865171 OpenAlex:https://openalex.org/W4322009528

UK Research and Innovation

Grant: MR/M024962/1

UKDP: Integrated DEmentiA research environment (IDEA)

National Institutes of Health

Grant: 1R01NS121608-01

Development of Mass Spectrometry Strategies to Decipher Dynamic Lysosomal Dysfunctions in Frontotemporal Dementia

Medical Research Council

Grant: MR/P007058/1

NINDS NIH HHS

Grant: R01 NS121608

Medical Research Council

Grant: MC_EX_MR/N50192X/1

Medical Research Council

Grant: MR/L023784/2

greenLicense: cc-by-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/02/24/2023.02.24.529955.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2023.02.24.529955

repositoryhttps://doi.org/10.1101/2023.02.24.529955

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36865171

Fields of Study

Amyotrophic Lateral Sclerosis ResearchGenetic Neurodegenerative DiseasesAlzheimer's disease research and treatments0301 basic medicine03 medical and health sciences0303 health sciences

Keywords

ProteostasisLysosomeCell biologyBiologyProteomicsStable isotope labeling by amino acids in cell cultureFunction (biology)ProteasomeBiochemistryGeneEnzymeProgranulinInduced Pluripotent Stem CellsArticleMiceProgranulinsAnimalsHumansRC346-429NeuronsRC952-954.6NeuronHalf-lifeTurnoverGeriatricsFrontotemporal DementiaIntercellular Signaling Peptides and ProteinsNeurology. Diseases of the nervous systemLysosomesResearch Article

Sustainable Development Goals

SDG 3: 3. Good health