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CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.19.545603Source: DataRank Database

CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2023). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (3 grants)OA: greenTopics (36)IDs (PubMed, OpenAlex)SDGs (1)

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Authors (7)

Atharv S. Garje ORCID,Swati Balakrishnan ORCID,Florian Morati ORCID,Mauro Modesti ORCID,Walter Chazin ORCID

Live enrichment

PubMed:37572935 OpenAlex:https://openalex.org/W4381377899

National Institutes of Health

Grant: 5R01GM116616-11

Analysis of the Replication Stress Response

National Institutes of Health

Grant: 5R35GM118089-07

Integrative Structural Biology in DNA Replication and Damage Response

National Institutes of Health

Grant: 3P01CA092584-19S1

Structural Cell Biology of DNA Repair Machines

Influential Citations

greenLicense: Elsevier TDM

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/06/19/2023.06.19.545603.full.pdf

GREENhttps://www.biorxiv.org/content/biorxiv/early/2023/06/19/2023.06.19.545603.full.pdf

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/06/19/2023.06.19.545603.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2023.06.19.545603

repositoryhttp://dx.doi.org/10.1101/2023.06.19.545603

Fields of Study

CRISPR and Genetic EngineeringDNA Repair MechanismsPluripotent Stem Cells ResearchBiologyMedicine0301 basic medicine03 medical and health sciences

Keywords

RAD51BiologyHomologous recombinationChromatinGenome instabilityMutantCell biologyCRISPRDNAReplication protein ADNA damageDNA replicationDNA repairGeneticsGeneDNA-binding proteinTranscription factorGene EditingReplication stressDNA, Single-StrandedGenomic Instabilitysingle-stranded DNA binding protein[SDV] Life Sciences [q-bio]Adenosine TriphosphateGenome stabilityHumansClustered Regularly Interspaced Short Palindromic RepeatsRad51 RecombinaseRNA Editing

Sustainable Development Goals

SDG 0: Good health and well-being