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Highly biased agonism for GPCR ligands via nanobody tethering

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.10.561766Source: DataRank Database

Highly biased agonism for GPCR ligands via nanobody tethering is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2023). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (2 grants)OA: greenTopics (26)IDs (PubMed, OpenAlex)

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Authors (4)

Brendan A. Creemer,Thomas J. Gardella ORCID,Ross W. Cheloha ORCID,Shivani Sachdev ORCID

Live enrichment

PubMed:37873435 OpenAlex:https://openalex.org/W4387641563

National Institutes of Health

Grant: 1ZIADK075157-02

New tools from chemistry and antibodies to address receptor function

National Institutes of Health

Grant: 5P01DK011794-24

HORMONAL CONTROL OF CALCIUM METABOLISM

greenLicense: CC BY

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/10/13/2023.10.10.561766.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2023.10.10.561766

repositoryhttps://doi.org/10.1101/2023.10.10.561766

repositoryhttps://pubmed.ncbi.nlm.nih.gov/37873435

Fields of Study

Receptor Mechanisms and SignalingMonoclonal and Polyclonal Antibodies ResearchNeuropeptides and Animal Physiology

Keywords

G protein-coupled receptorFunctional selectivityAgonistSignal transductionReceptorChemistryLigand (biochemistry)Cell biologyTetheringBiologyBiochemistryHEK293 CellsScienceQHumansAnimalsSingle-Domain AntibodiesLigandsPeptidesArticleReceptor, Parathyroid Hormone, Type 1Receptors, G-Protein-CoupledProtein Binding