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Discovery of RNA-Reactive Small Molecules Guides Design of Electrophilic Modules for RNA-Specific Covalent Binders

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.22.649986Source: DataRank Database

Discovery of RNA-Reactive Small Molecules Guides Design of Electrophilic Modules for RNA-Specific Covalent Binders is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)OA: greenTopics (23)IDs (PubMed, OpenAlex)

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Authors (5)

Patrick R. A. Zanon ORCID,Amirhossein Taghavi ORCID,Kisu Sung ORCID,Matthew D. Disney ORCID,Noah A. Springer ORCID

Live enrichment

PubMed:19965766 OpenAlex:https://openalex.org/W4409694144

National Institutes of Health

Grant: NS116846

Muscular Dystrophy Association

Grant: 1069959

National Science Foundation

Grant: 2235200

Graduate Research Fellowship Program (GRFP)

Deutsche Forschungsgemeinschaft

Grant: 515396515

National Institutes of Health

Grant: 1R35NS116846-01

Design of precision small molecules targeting RNA repeating transcripts to manipulate and study disease biology

Deutsche Forschungsgemeinschaft

Grant: unidentified

unidentified

greenLicense: CC BY NC ND

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2025/04/22/2025.04.22.649986.full.pdf

repositoryhttps://doi.org/10.1101/2025.04.22.649986

https://doi.org/10.1021/jacs.5c06802

https://pubmed.ncbi.nlm.nih.gov/40951988

https://pubmed.ncbi.nlm.nih.gov/40951988/

Fields of Study

Chemistry and Chemical Engineering01 natural sciences0104 chemical sciences

Keywords

RNAElectrophileCovalent bondChemistryCombinatorial chemistryComputational biologyNanotechnologyBiochemistryBiologyMaterials scienceOrganic chemistryGeneCatalysisSmall Molecule LibrariesMolecular StructureDrug DesignDrug DiscoveryBenzimidazolesLigandsArticle