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AMPK regulation of Raptor and TSC2 mediate metformin effects on transcriptional control of anabolism and inflammation

Genes & Development(2020)10.1101/gad.339895.120Source: DataRank Database

AMPK regulation of Raptor and TSC2 mediate metformin effects on transcriptional control of anabolism and inflammation is a research paper published in Genes & Development (2020). On theSindex it has a DataRank of 0. It has been cited 101 times.

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Open Access101 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (12 grants)OA: goldTopics (76)IDs (PubMed, PMC)SDGs (1)

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Accessible (1/2)

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Authors (10)

Kristina Hellberg ORCID,En‐Ching Luo ORCID,Eric L. Van Nostrand ORCID,Alina Dayn,Jingting Yu ORCID

Live enrichment

PubMed:32912901 PMC:PMC7528705

National Institutes of Health

Grant: R01-DK080425

National Institutes of Health

Grant: R35-CA220538

National Institutes of Health

Grant: P01-CA120964

Damon Runyan Cancer Research Foundation

Grant: DRG 2219-15

NCI NIH HHS

Grant: P01 CA120964

NIDDK NIH HHS

Grant: R01 DK080425

NCI NIH HHS

Grant: P30 CA014195

NCI NIH HHS

Grant: R35 CA220538

NHGRI NIH HHS

Grant: K99 HG009530

National Institutes of Health

Grant: 2R01DK080425-06

LKB1- AMPK pathway regulation of glucose metabolism and metformin action in liver

National Institutes of Health

Grant: 5R35CA220538-06

Decoding And Targeting The LKB1-AMPK Signaling Pathway In Cancer

National Institutes of Health

Grant: 2P01CA120964-06A1

Molecular wiring and therapeutic targeting of the TSC-Rheb signaling network

goldLicense: cc-by-nc

publisherhttp://genesdev.cshlp.org/content/34/19-20/1330.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/gad.339895.120

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7528705

Europe_PMChttps://europepmc.org/articles/PMC7528705

Europe_PMChttps://europepmc.org/articles/PMC7528705?pdf=render

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciencesAMP-Activated Protein KinasesAnimalsDiabetes Mellitus, Type 2Disease Models, AnimalGene Expression RegulationGene Knock-In TechniquesGenotypeHypoglycemic AgentsInflammationMechanistic Target of Rapamycin Complex 1MetabolismMetforminMicePhosphorylationRegulatory-Associated Protein of mTORSignal TransductionTOR Serine-Threonine KinasesTuberous Sclerosis Complex 2 Protein

MeSH Terms

AnimalsMiceDiabetes Mellitus, Type 2Disease Models, AnimalInflammationMetforminHypoglycemic AgentsSignal TransductionGene Expression RegulationMetabolismPhosphorylationGenotypeAMP-Activated Protein KinasesGene Knock-In TechniquesTOR Serine-Threonine KinasesMechanistic Target of Rapamycin Complex 1Regulatory-Associated Protein of mTORTuberous Sclerosis Complex 2 Protein

Keywords

Stat3RaptorMetforminMtorTsc2AmpkMedical SciencesGenotypeBiophysics610AMP-Activated Protein KinasesMechanistic Target of Rapamycin Complex 1BiochemistryMiceTuberous Sclerosis Complex 2 ProteinDiabetes MellitusMedical SpecialtiesMedicine and Health SciencesAnimalsHypoglycemic AgentsGene Knock-In TechniquesPhosphorylationBiologyInflammationAnimalTOR Serine-Threonine KinasesLife SciencesRegulatory-Associated Protein of mTORDisease Models, AnimalMetabolismDiabetes Mellitus, Type 2Gene Expression RegulationDisease Modelsand Structural BiologyType 2Research PaperSignal Transduction

Sustainable Development Goals

SDG 3: 3. Good health