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Sex-, Age-, and Race/Ethnicity-Dependent Variations in Drug-Processing and NRF2-Regulated Genes in Human Livers

Drug Metabolism and Disposition(2020)10.1124/dmd.120.000181Source: DataRank Database

Sex-, Age-, and Race/Ethnicity-Dependent Variations in Drug-Processing and NRF2-Regulated Genes in Human Livers is a research paper published in Drug Metabolism and Disposition (2020). On theSindex it has a DataRank of 0. It has been cited 24 times.

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Open Access24 citations

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ORD-037657: Sex-, age-, race-, and disease-dependent variations in NRF2-regulated genes in human livers · U.S. EPA Office of Research and Development (ORD)

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)Impact (FWCI 0.99)OA: bronzeTopics (78)Linked Datasets (1)DataCite Reuse (1)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (3)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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Authors (5)

Julia Yue Cui ORCID,Yuan‐Fu Lu ORCID,J. Christopher Corton ORCID,Curtis D. Klaassen,Jie Liu ORCID

Live enrichment

PubMed:33162398 PMC:PMC7804821 OpenAlex:https://openalex.org/W3100952768

NIEHS NIH HHS

Grant: R01 ES013714

NCRR NIH HHS

Grant: P20 RR021940

NIDDK NIH HHS

Grant: R01 DK081461

NIEHS NIH HHS

Grant: R01 ES009649

NIEHS NIH HHS

Grant: P30 ES007033

NIEHS NIH HHS

Grant: R01 ES009716

NIEHS NIH HHS

Grant: T32 ES007079

National Institutes of Health

Grant: 5P20RR021940-04

CORE F CENTER JOINT PROJECTS

FWCI

0.99

Citation Percentile

0.8%

Citation Trend

2021

2022

2023

2024

2025

2026

bronzeLicense: Elsevier TDM

journalhttps://dmd.aspetjournals.org/content/dmd/49/1/111.full.pdf

publisherhttps://dmd.aspetjournals.org/content/dmd/49/1/111.full.pdf

publisherhttps://api.elsevier.com/content/article/PII:S0090955624077304?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0090955624077304?httpAccept=text/plain

publisherhttps://syndication.highwire.org/content/doi/10.1124/dmd.120.000181

Fields of Study

Drug Transport and Resistance MechanismsGenomics, phytochemicals, and oxidative stressGlutathione Transferases and Polymorphisms0301 basic medicine0303 health sciences03 medical and health sciencesAdultAge FactorsAgedChildCytochrome P-450 Enzyme SystemFemaleGene Expression ProfilingHepatobiliary EliminationHumansLiverLiver DiseasesMaleMembrane Transport ProteinsNF-E2-Related Factor 2Pharmaceutical PreparationsPharmacogenomic TestingPharmacokineticsRace FactorsReceptors, Cytoplasmic and NuclearSex Factors

MeSH Terms

Pharmacogenomic TestingRace FactorsAdultAge FactorsAgedChildCytochrome P-450 Enzyme SystemPharmaceutical PreparationsFemaleHumansLiverLiver DiseasesMalePharmacokineticsSex FactorsReceptors, Cytoplasmic and NuclearGene Expression ProfilingMembrane Transport ProteinsNF-E2-Related Factor 2Hepatobiliary Elimination

Keywords

GCLCGCLMBiologyDrug metabolismMolecular biologyPregnane X receptorBiochemistryGeneNuclear receptorProtein subunitMetabolismTranscription factorAdultMaleNF-E2-Related Factor 2Gene Expression ProfilingLiver DiseasesAge FactorsMembrane Transport ProteinsReceptors, Cytoplasmic and NuclearPharmacogenomic TestingRace FactorsHepatobiliary EliminationSex FactorsCytochrome P-450 Enzyme SystemLiverPharmaceutical PreparationsHumansFemalePharmacokineticsChildAged

Sustainable Development Goals

SDG 3: 3. Good healthSDG 10: 10. No inequalitySDG 0: Good health and well-being

ORD-037657: Sex-, age-, race-, and disease-dependent variations in NRF2-regulated genes in human livers

10.23719/1518913U.S. EPA Office of Research and Development (ORD)

Sex-, Age-, and Race/Ethnicity-Dependent Variations in Drug-Processing and NRF2-Regulated Genes in Human Livers

FAIR Checklist

Authors (5)

Funding (8 grants)

Impact

Open Access

Topics

Linked Datasets (1)

Annotations (Europe PMC)