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In vitro modeling of CD8 + T cell exhaustion enables CRISPR screening to reveal a role for BHLHE40

Science Immunology(2023)10.1126/sciimmunol.ade3369Source: DataRank Database

In vitro modeling of CD8 + T cell exhaustion enables CRISPR screening to reveal a role for BHLHE40 is a research paper published in Science Immunology (2023). On theSindex it has a DataRank of 0. It has been cited 94 times.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (22 grants)OA: greenTopics (19)IDs (PubMed, PMC)SDGs (1)

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Authors (15)

Sasikanth Manne ORCID,Shin Foong Ngiow ORCID,Amy E. Baxter ORCID,Hua Huang ORCID,Elizabeth Freilich ORCID

Live enrichment

PubMed:37595022 PMC:PMC11975459

NIAID NIH HHS

Grant: R01 AI155577

NIAID NIH HHS

Grant: F30 AI129263

NCI NIH HHS

Grant: F99 CA234842

NIAID NIH HHS

Grant: P01 AI108545

NCI NIH HHS

Grant: P01 CA210944

NIAMS NIH HHS

Grant: T32 AR007442

NIAID NIH HHS

Grant: U19 AI082630

NCI NIH HHS

Grant: K00 CA234842

NIAID NIH HHS

Grant: U19 AI117950

NCI NIH HHS

Grant: T32 CA009140

NIDDK NIH HHS

Grant: T32 DK007780

NIAID NIH HHS

Grant: R01 AI115712

National Institutes of Health

Grant: 2U19AI082630-06

Reversal of Immune Failure with Viral Cure in Chronic HCV Infection

National Institutes of Health

Grant: 1F30AI129263-01

The Role of Tox in Regulating T Cell Exhaustion

National Institutes of Health

Grant: 5F99CA234842-02

Investigating molecular mechanism of T cell exhaustion in chronic infection and tumor microenvironment

National Institutes of Health

Grant: 5P01AI108545-08

Synergies among inhibitory receptors in tolerance, cancer & antiviral immunity

National Institutes of Health

Grant: 4T32AR007442-29

Training Program/Rheumatic Diseases

National Institutes of Health

Grant: 5R01AI155577-02

Temporal control of differentiation and epigenetics of Exhausted CD8 T cells by Tox

National Institutes of Health

Grant: 5T32CA009140-12

IMMUNOBIOLOGY OF NORMAL AND NEOPLASTIC LYMPHOCYTES

National Institutes of Health

Grant: 5R01AI115712-02

Testing the role of BATF as a pioneer transcription factor in effector T cells

National Health and Medical Research Council (NHMRC)

Grant: 1111469

Molecular regulation of Tim3 signalling in T cells

National Institutes of Health

Grant: 5U19AI117950-02

Engineering T cells to Provide Durable Control of HIV-1 Replication

greenLicense: CC BY NC ND

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11975459/pdf/nihms-2070828.pdf

publisherhttps://www.science.org/doi/pdf/10.1126/sciimmunol.ade3369

https://doi.org/10.1126/sciimmunol.ade3369

https://doi.org/10.1101/2023.04.17.537229

https://pubmed.ncbi.nlm.nih.gov/37131713

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciencesClustered Regularly Interspaced Short Palindromic RepeatsT-Cell ExhaustionCD8-Positive T-LymphocytesCell DifferentiationEpigenomics

MeSH Terms

CD8-Positive T-LymphocytesCell DifferentiationEpigenomicsClustered Regularly Interspaced Short Palindromic RepeatsT-Cell Exhaustion

Keywords

EpigenomicsClustered Regularly Interspaced Short Palindromic RepeatsCell DifferentiationCD8-Positive T-LymphocytesArticleT-Cell Exhaustion

Sustainable Development Goals

SDG 3: 3. Good health