lacY mutant of Escherichia coli with altered physiology of lactose induction is a research paper published in Journal of Bacteriology (1976). On theSindex it has a DataRank of 0.754. It has been cited 8 times, with 7 citing works in its 1-hop citation network.
A mutant of Escherichia coli is described that grew on lactose only in the presence of isopropylthiogalactoside. This cell contained a defect in the lacY gene that resulted in the formation of a transport system with a poor affinity for lactose. The inability to grow on lactose alone was due to the failure of induction by this disaccharide. This failure of inducation was presumably due to a defect in lactose accumulation which resulted in significant reduction in the formation of allo-lactose, the true inducer of lac operon. These results are consistent with the view that the capacity to accumulate lactose plays an important physiological role in the induction of the enzymes necessary for its utilization.
FAIR checklist signals are shown for context only and do not affect DataRank scoring.
Base Score Contribution
0.330
From this paper's citation signal
Citation Network Contribution
0.425
From 6 citing papers with measurable signal
Ranked by citation count — the same ordering the engine uses when summing log1p(Cq) over citers.
DataRank blends this paper's own citation count with the influence of the papers that cite it. Here, roughly 44% comes from its base citations and 56% from the citation network (6 citing papers contributed measurable signal).
Citers are pulled from OpenAlex sorted by cited_by_count:descand capped per paper, so when the cap binds we keep the highest-signal references and the score is reproducible across reruns.
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