Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

A Comparative Analysis of SARS-CoV-2 Antivirals Characterizes 3CL pro Inhibitor PF-00835231 as a Potential New Treatment for COVID-19

Journal of Virology(2021)10.1128/jvi.01819-20Source: DataRank Database

A Comparative Analysis of SARS-CoV-2 Antivirals Characterizes 3CL pro Inhibitor PF-00835231 as a Potential New Treatment for COVID-19 is a research paper published in Journal of Virology (2021). On theSindex it has a DataRank of 5.2. It has been cited 142 times, with 129 citing works in its 1-hop citation network.

N/A

5.2DataRank · unranked

Scored on demand from live citation data

Open Access142 citations · 129 citing works in its network

Download PDF

Cite:

Linked data & code

geo gen

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)OA: hybridLinked Datasets (2)DataCite Reuse (2)IDs (PubMed, PMC)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

DataRank Breakdown

Base Score 14%Citation Network 86%

Base Score Contribution

0.744

From this paper's citation signal

Citation Network Contribution

4.4

From 113 citing papers with measurable signal

Learn more about DataRank methodology →

Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 129 citers.

Inhibition Mechanism of SARS‐CoV‐2 Main Protease with Ketone‐Based Inhibitors Unveiled by Multiscale Simulations: Insights for Improved Designs**
Angewandte Chemie International Edition202149 citations23 referencesContributes 0.170
Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir
Nature Communications2023108 citations32 referencesContributes 0.147
Nirmatrelvir plus ritonavir (Paxlovid) a potent SARS-CoV-2 3CLpro protease inhibitor combination
Revista Española de Quimioterapia202261 citations31 referencesContributes 0.133
Total synthesis of antiviral drug, nirmatrelvir (PF-07321332)
Tetrahedron Chem202231 citations30 referencesContributes 0.116
SARS-CoV-2 Subgenomic RNA Kinetics in Longitudinal Clinical Samples
Open Forum Infectious Diseases202133 citations33 referencesContributes 0.107

Authors (17)

Adil Mohamed ORCID,Rachel A. Prescott ORCID,Ana M. Valero-Jimenez ORCID,Ludovic Desvignes ORCID,Rebecca E. O’Connor ORCID

Live enrichment

PubMed:33622961 PMC:PMC8139662

HHS | NIH | NIAID | Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases

Grant: R01AI143639

HHS | NIH | National Institute of Allergy and Infectious Diseases

Grant: R21AI139374

HHS | National Institutes of Health

Grant: R01HL125816

Pfizer

Grant: Research contract

Vilcek Foundation

Grant: Jan Vilcek/David Goldfarb Fellowship Endowment Funds

NCI NIH HHS

Grant: P30 CA016087

NYUCI Pilot grant

G. Harold and Leila Y. Mathers Foundation

hybridLicense: cc-by

publisherhttps://doi.org/10.1128/jvi.01819-20

publisherhttps://journals.asm.org/doi/pdf/10.1128/JVI.01819-20

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8139662

Europe_PMChttps://europepmc.org/articles/PMC8139662

Europe_PMChttps://europepmc.org/articles/PMC8139662?pdf=render

Additional file 1 of Beyond the vaccines: a glance at the small molecule and peptide-based anti-COVID19 arsenal

10.6084/m9.figshare.20962344.v1figshare

Additional file 1 of Beyond the vaccines: a glance at the small molecule and peptide-based anti-COVID19 arsenal

10.6084/m9.figshare.20962344figshare

Related Papers (10)

Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2

N/A

14.4DataRank · unranked

Nature(2020)

co-cited

10.1038/s41586-020-2423-5

SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801

N/A

14.1DataRank · unranked

Nature(2021)

co-cited

10.1038/s41586-021-03312-w

Characterization and antiviral susceptibility of SARS-CoV-2 Omicron BA.2

N/A

10.7DataRank · unranked

Nature(2022)

co-cited

10.1038/s41586-022-04856-1

Discovery of a Novel Inhibitor of Coronavirus 3CL Protease for the Potential Treatment of COVID-19

N/A

5.5DataRank · unranked

bioRxiv (Cold Spring Harbor Laboratory)(2020)

co-cited

10.1101/2020.09.12.293498

Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

N/A

1.4DataRank · unranked

New England Journal of Medicine(2020)

co-cited

10.1056/nejmoa2034577

Clinical Characteristics of Coronavirus Disease 2019 in China

Top 1%

30.3DataRank

New England Journal of Medicine(2020)

co-cited

10.1056/nejmoa2002032

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

N/A

1.3DataRank · unranked

Cell(2020)

co-cited

10.1016/j.cell.2020.04.026

Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants

N/A

19.9DataRank · unranked

eLife(2020)

co-cited

10.7554/elife.61312

SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2

N/A

11.0DataRank · unranked

Cell(2020)

co-cited

10.1016/j.cell.2020.09.033

Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease

N/A

1.0DataRank · unranked

Cell Research(2020)

co-cited

10.1038/s41422-020-0356-z

A Comparative Analysis of SARS-CoV-2 Antivirals Characterizes 3CL pro Inhibitor PF-00835231 as a Potential New Treatment for COVID-19

FAIR Checklist

DataRank Breakdown

Top 5 citers driving the network score

Authors (17)

Funding (8 grants)

Open Access

Linked Datasets (2)

Annotations (Europe PMC)

Related Papers (10)