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Large-scale analysis of disease pathways in the human interactome

Biocomputing 2018(2018)10.1142/9789813235533_0011Source: DataRank Database

Large-scale analysis of disease pathways in the human interactome is a research paper published in Biocomputing 2018 (2018). On theSindex it has a DataRank of 0.796. It has been cited 32 times, with 15 citing works in its 1-hop citation network.

N/A

0.796DataRank · unranked

Scored on demand from live citation data

32 citations · 15 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (1 grants)Impact (FWCI 8.09)OA: goldTopics (42)IDs (PubMed, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (0/2)

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 66%Citation Network 34%

Base Score Contribution

0.524

From this paper's citation signal

Citation Network Contribution

0.272

From 10 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 15 citers.

Disease Module Identification Based on Representation Learning of Complex Networks Integrated From GWAS, eQTL Summaries, and Human Interactome
Frontiers in Bioengineering and Biotechnology202030 citations72 referencesContributes 0.048
Drug repurposing for COVID-19 using computational screening: Is Fostamatinib/R406 a potential candidate?
Methods202126 citations71 referencesContributes 0.046
Detection of spreader nodes and ranking of interacting edges in Human-SARS-CoV protein interaction network
bioRxiv (Cold Spring Harbor Laboratory)20203 citations30 referencesContributes 0.046
Pairwise link prediction
20193 citations37 referencesContributes 0.037
Dysregulation of phosphoproteins in hepatocellular carcinoma revealed via quantitative analysis of the phosphoproteome
Oncology Letters202011 citations68 referencesContributes 0.037

Authors (3)

Marinka Zitnik ORCID,Jure Leskovec ORCID,Monica Agrawal

Live enrichment

PubMed:29218874 OpenAlex:https://openalex.org/W2754104053

National Science Foundation

Grant: 1149837

CAREER: Mining structure and dynamics of groups of nodes in real-world networks

FWCI

8.09

Citation Percentile

1.0%

Citation Trend

2018

2019

2020

2021

2022

2023

goldLicense: cc-by-nc

https://doi.org/10.1142/9789813235533_0011

repositoryhttps://doi.org/10.1101/189787

repositoryhttps://pubmed.ncbi.nlm.nih.gov/29218874

repositoryhttp://arxiv.org/abs/1712.00843

Fields of Study

Bioinformatics and Genomic NetworksComputational Drug Discovery MethodsBiomedical Text Mining and Ontologies0301 basic medicine0206 medical engineering02 engineering and technology03 medical and health sciences

MeSH Terms

AlgorithmsDiseaseHumansSignal TransductionComputational BiologyProteomeProtein Interaction MappingProteomicsProtein Interaction Maps

Keywords

InteractomeDiseaseComputational biologyDrug discoveryComputer scienceBiologyInteraction networkBioinformaticsGeneticsMedicineGeneProteomicsSocial and Information Networks (cs.SI)FOS: Computer and information sciencesComputer Science - Machine LearningProteomeMolecular Networks (q-bio.MN)Computer Science - Social and Information NetworksMachine Learning (cs.LG)FOS: Biological sciencesProtein Interaction MappingHumansQuantitative Biology - Molecular NetworksProtein Interaction MapsAlgorithmsSignal Transduction

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: No poverty