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Aortic Cellular Diversity and Quantitative Genome-Wide Association Study Trait Prioritization Through Single-Nuclear RNA Sequencing of the Aneurysmal Human Aorta

Arteriosclerosis Thrombosis and Vascular Biology(2022)10.1161/atvbaha.122.317953Source: DataRank Database

Aortic Cellular Diversity and Quantitative Genome-Wide Association Study Trait Prioritization Through Single-Nuclear RNA Sequencing of the Aneurysmal Human Aorta is a research paper published in Arteriosclerosis Thrombosis and Vascular Biology (2022). On theSindex it has a DataRank of 1.7. It has been cited 53 times, with 50 citing works in its 1-hop citation network.

N/A

1.7DataRank · unranked

Scored on demand from live citation data

Open Access53 citations · 50 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (9 grants)OA: bronzeTopics (28)IDs (PubMed, PMC)Annotations (3)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 36%Citation Network 64%

Base Score Contribution

0.598

From this paper's citation signal

Citation Network Contribution

1.1

From 38 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 50 citers.

Genetic Epidemiology Highlights the Role of Aortic Strain and Distensibility in Cardiovascular Disease
Journal of the American College of Cardiology20232 citations7 referencesContributes 0.157
Editorial: Lipid metabolism and human diseases
Frontiers in Physiology20221 citations5 referencesContributes 0.139
New Genomic Techniques Provide Novel Insights Into Ascending Aortic Aneurysm Pathology
Arteriosclerosis Thrombosis and Vascular Biology20221 citations8 referencesContributes 0.087
High-Dimensional Single-Cell Multimodal Landscape of Human Carotid Atherosclerosis
Arteriosclerosis Thrombosis and Vascular Biology202497 citations73 referencesContributes 0.063
Single‐Nucleus Multiomic Analyses Identifies Gene Regulatory Dynamics of Phenotypic Modulation in Human Aneurysmal Aortic Root
Advanced Science20245 citations36 referencesContributes 0.050

Authors (16)

Mark Chaffin ORCID,Bridget Simonson ORCID,James P. Pirruccello ORCID,Amer-Denis Akkad ORCID,Mahan Nekoui ORCID

Live enrichment

PubMed:36172868 PMC:PMC9613617

NHLBI NIH HHS

Grant: R01 HL092577

NHLBI NIH HHS

Grant: R01 HL130113

NHLBI NIH HHS

Grant: R01 HL157635

NHLBI NIH HHS

Grant: K08 HL159346

NHLBI NIH HHS

Grant: T32 HL007208

NHLBI NIH HHS

Grant: K01 HL164687

NHLBI NIH HHS

Grant: K24 HL105780

NIAMS NIH HHS

Grant: R21 AR080778

NHLBI NIH HHS

Grant: R01 HL105993

bronze

publisherhttps://www.ahajournals.org/doi/pdf/10.1161/ATVBAHA.122.317953

publisherhttps://www.ahajournals.org/doi/full/10.1161/ATVBAHA.122.317953

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9613617

Fields of Study

HumansGenome-Wide Association StudyMuscle, Smooth, VascularActininRNA, NuclearAortaMyocytes, Smooth MuscleAortic Aneurysm, ThoracicAortic AneurysmSequence Analysis, RNATransforming Growth Factor beta

MeSH Terms

Muscle, Smooth, VascularAortaMyocytes, Smooth MuscleHumansAortic AneurysmAortic Aneurysm, ThoracicTransforming Growth Factor betaActininRNA, NuclearSequence Analysis, RNAGenome-Wide Association Study

Keywords

FibroblastExtracellular matrixthoracicGenome-wide Association StudyAortic AneurysmsTranscriptomes