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Mocetinostat activates Krüppel-like factor 4 and protects against tissue destruction and inflammation in osteoarthritis

JCI Insight(2023)10.1172/jci.insight.170513Source: DataRank Database

Mocetinostat activates Krüppel-like factor 4 and protects against tissue destruction and inflammation in osteoarthritis is a research paper published in JCI Insight (2023). On theSindex it has a DataRank of 0. It has been cited 25 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access25 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 2.48)OA: goldTopics (58)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Daniel B. McClatchy ORCID,Jolene K. Diedrich ORCID,Merissa Olmer ORCID,Kristen Johnson ORCID,John R. Yates ORCID

Live enrichment

PubMed:37681413 PMC:PMC10544226 OpenAlex:https://openalex.org/W4386524475

National Institutes of Health

Grant: R01AG049617

National Institutes of Health

Grant: R01AG056144

NIA NIH HHS

Grant: R37 AG059418

Fundação para a Ciência e a Tecnologia, I.P.

Grant: PTDC/CCI-INF/6762/2020

MS3: New foundations for micro-services and serverless systems

National Institutes of Health

Grant: 5R01AG049617-04

Integrative Omics analysis of human cartilage in aging and osteoarthritis

National Institutes of Health

Grant: 5R01AG056144-03

KLF4 in joint degradation and regeneration

FWCI

2.48

Citation Percentile

0.9%

Citation Trend

2024

2025

2026

goldLicense: cc-by

journalhttp://insight.jci.org/articles/view/170513/files/pdf

publisherhttp://insight.jci.org/articles/view/170513/files/pdf

publisherhttps://insight.jci.org/articles/view/170513/files/pdf

journalhttps://doi.org/10.1172/jci.insight.170513

repositoryhttps://pubmed.ncbi.nlm.nih.gov/37681413

Fields of Study

Kruppel-like factors researchCancer-related gene regulationMicroRNA in disease regulation0303 health sciences03 medical and health sciencesHumansAnimalsMiceKruppel-Like Factor 4OsteoarthritisInflammationHistone Deacetylase InhibitorsBone NeoplasmsBenzamidesPyrimidines

MeSH Terms

Kruppel-Like Factor 4AnimalsBenzamidesBone NeoplasmsHumansInflammationOsteoarthritisPyrimidinesMiceHistone Deacetylase Inhibitors

Keywords

KLF4Cancer researchOsteoarthritisInflammationMesenchymal stem cellDownregulation and upregulationRegenerative medicineCartilageCell biologyTranscription factorHistone deacetylaseChemistryMedicineBiologyStem cellImmunologyPathologySOX2HistoneGeneBiochemistryAnatomyBone BiologyRBone NeoplasmsHistone Deacetylase InhibitorsMiceKruppel-Like Factor 4PyrimidinesBenzamidesHumansAnimalsResearch Article

Sustainable Development Goals

SDG 0: Good health and well-being