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Quinolinic acid potentially links kidney injury to brain toxicity

JCI Insight(2025)10.1172/jci.insight.180229Source: DataRank Database

Quinolinic acid potentially links kidney injury to brain toxicity is a research paper published in JCI Insight (2025). On theSindex it has a DataRank of 0. It has been cited 15 times.

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Open Access15 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (23 grants)Impact (FWCI 11.07)OA: goldTopics (62)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (22)

Subrata Debnath ORCID,Ian M. Tamayo ORCID,Hak Joo Lee ORCID,Nagarjunachary Ragi,Falguni Das

Live enrichment

PubMed:39946208 PMC:PMC11949017 OpenAlex:https://openalex.org/W4407509306

National Center for Advancing Translational Sciences

Grant: TL1 TR002647

National Institutes of Health

Grant: T32 HL007446

U.S. Department of Defense

Grant: W81XWH1910659

National Institute of Diabetes and Digestive and Kidney Diseases

Grant: 5U01DK114920-06

University of Texas Health Science Center at San Antonio

Grant: Multi-PI pilot grant 2023-2024,Long School of Medicine

National Institute of Neurological Disorders and Stroke

Grant: K01NS126489

South Texas Alzheimer’s Disease Research Center

Grant: P30AG066546

National Institutes of Health

Grant: K01- AG066747

National Institute of Health Sciences

Grant: T32-AG021890

BLRD VA

Grant: I01 BX003195

BLRD VA

Grant: I01 BX001340

BLRD VA

Grant: I01 BX003234

NIDDK NIH HHS

Grant: U01 DK114920

NIA NIH HHS

Grant: K01 AG066747

NIA NIH HHS

Grant: T32 AG021890

National Institutes of Health

Grant: 1P30AG066546-01A1

South Texas Alzheimer's Disease Center

National Institutes of Health

Grant: 1TL1TR002647-01

NRSA Training Core (TL1)

National Institutes of Health

Grant: 5K01NS126489-02

Delineating the role of the gut microbiota and its derived metabolites in the development of dementia in multi-ethnic populations

National Institutes of Health

Grant: 5U01DK114920-07

Spatial Multi-Omics to Profile Metabolic Pathways for Kidney Disease

National Institutes of Health

Grant: 2I01BX001340-09A1

New Insights in Mechanisms of Renal Injury

National Institutes of Health

Grant: 5T32AG021890-08

TRAINING GRANT ON THE BIOLOGY OF AGING

National Institutes of Health

Grant: 2T32HL007446-31

Pathobiology of Occlusive Vascular Disease

National Institutes of Health

Grant: 5K01AG066747-04

Dysregulated intracellular calcium in microglia during Alzheimer's disease

FWCI

11.07

Citation Percentile

1.0%

Citation Trend

2024

2025

2026

goldLicense: cc-by

journalhttp://insight.jci.org/articles/view/180229/files/pdf

publisherhttp://insight.jci.org/articles/view/180229/files/pdf

publisherhttps://insight.jci.org/articles/view/180229/files/pdf

journalhttps://doi.org/10.1172/jci.insight.180229

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39946208

Fields of Study

Metabolism and Genetic DisordersEpilepsy research and treatmentDrug-Induced Hepatotoxicity and Protection03 medical and health sciences0302 clinical medicineQuinolinic AcidAnimalsMiceAcute Kidney InjuryHumansKynurenineBrainTryptophanMaleDisease Models, AnimalMetabolomicsFemaleRenal Insufficiency, ChronicKidneyMice, Inbred C57BL

MeSH Terms

AnimalsBrainDisease Models, AnimalFemaleHumansKidneyKynurenineMaleMice, Inbred C57BLTryptophanQuinolinic AcidMiceRenal Insufficiency, ChronicMetabolomicsAcute Kidney Injury

Keywords

ToxicityQuinolinic acidKidneyPharmacologyMedicineChemistryInternal medicineBiochemistryNeuroscienceAmino Acid MetabolismChronic Kidney DiseaseNephrologyNeurological DisordersMaleTryptophanBrainAcute Kidney InjuryMice, Inbred C57BLMiceDisease Models, AnimalAnimalsHumansMetabolomicsFemaleRenal Insufficiency, ChronicKynurenineResearch Article

Sustainable Development Goals

SDG 0: Good health and well-being