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Structures of RNA phosphotransferase Tpt1 reveal distinct binding modes for an RNA 2′-PO4splice junction versus a 5′-PO4mononucleotide

RNA(2025)10.1261/rna.080444.125Source: DataRank Database

Structures of RNA phosphotransferase Tpt1 reveal distinct binding modes for an RNA 2′-PO4splice junction versus a 5′-PO4mononucleotide is a research paper published in RNA (2025). On theSindex it has a DataRank of 0. It has been cited 2 times.

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0DataRank · unranked

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Open Access2 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 0.83)OA: greenTopics (38)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (3)

Masad J. Damha ORCID,Stewart Shuman ORCID,Agata Jacewicz ORCID

Live enrichment

PubMed:40324821 OpenAlex:https://openalex.org/W4410089894

NIGMS NIH HHS

Grant: R35 GM126945

NCI NIH HHS

Grant: P30 CA008748

NIGMS NIH HHS

Grant: P30 GM124165

NIH HHS

Grant: S10 OD021527

FWCI

0.83

Citation Percentile

0.7%

Citation Trend

2025

greenLicense: cc-by-nc

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12170183/

publisherhttps://syndication.highwire.org/content/doi/10.1261/rna.080444.125

journalhttps://doi.org/10.1261/rna.080444.125

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40324821

Fields of Study

RNA modifications and cancerBiochemical and Molecular ResearchRNA and protein synthesis mechanismsRNAProtein BindingCrystallography, X-RayModels, MolecularBinding SitesHumansRNA SplicingNucleic Acid Conformation

MeSH Terms

Binding SitesHumansModels, MolecularNucleic Acid ConformationProtein BindingRNARNA SplicingCrystallography, X-Ray

Keywords

RNAPhosphodiester bondRiboseBiologyNucleoside triphosphateNAD+ kinaseBiochemistryRNA ligaseNucleic acidNucleotideNucleosidePhosphotransferaseEnzymeStereochemistryChemistryGeneNicotinamide Adenine DinucleotideTrna SplicingAdp-ribosyl Transfer

Sustainable Development Goals

SDG 0: Clean water and sanitation