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Guidelines for performing Mendelian randomization investigations

Wellcome Open Research(2020)10.12688/wellcomeopenres.15555.2Source: DataRank Database

Guidelines for performing Mendelian randomization investigations is a research paper published in Wellcome Open Research (2020). On theSindex it has a DataRank of 12.9. It has been cited 1,353 times, with 200 citing works in its 1-hop citation network.

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12.9DataRank · unranked

Scored on demand from live citation data

Open Access1,353 citations · 200 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (9 grants)Impact (FWCI 112.88)OA: goldTopics (19)Linked Datasets (25)DataCite Reuse (25)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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DataRank Breakdown

Base Score 8%Citation Network 92%

Base Score Contribution

1.1

From this paper's citation signal

Citation Network Contribution

11.8

From 200 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 200 citers.

Why clinicians should know about Mendelian randomization
Lara D. Veeken202135 citations14 referencesContributes 0.256
Independent Causal Effect of Remnant Cholesterol on Atherosclerotic Cardiovascular Outcomes: A Mendelian Randomization Study
Arteriosclerosis Thrombosis and Vascular Biology2023102 citations28 referencesContributes 0.166
Cardiac Risk Factors for Stroke: A Comprehensive Mendelian Randomization Study
Stroke202126 citations20 referencesContributes 0.165
Migraine and Ischemic Stroke: A Mendelian Randomization Study
Neurology and Therapy202184 citations28 referencesContributes 0.159
Peripheral level of CD33 and Alzheimer’s disease: a bidirectional two-sample Mendelian randomization study
Translational Psychiatry202253 citations27 referencesContributes 0.148

Authors (11)

George Davey Smith ORCID,Neil M. Davies ORCID,Frank Dudbridge ORCID,Dipender Gill ORCID,M. Maria Glymour ORCID

Live enrichment

PubMed:32760811 OpenAlex:https://openalex.org/W2991007563

Economic and Social Research Council

Grant: ES/N000757/1

Informing educational interventions using genome-wide data: causal evidence from 573,586 participants of eight cohort studies

Cancer Research UK

Grant: C31250/A22804

Wellcome Trust

Grant: 204623

Genetics and causality: towards more accessible and more reliable Mendelian randomization investigations

Medical Research Council

Grant: MC_UU_12013/9

Statistics and Econometrics Methodology

Medical Research Council

Grant: MC_UU_00011/1

Mendelian randomization to hypothesis-free causal inference

British Heart Foundation

Grant: FS/18/23/33512

Medical Research Council

Grant: MC_UU_00011/5

Epigenetic Epidemiology

Medical Research Council

Grant: MC_UU_12013/1

From Mendelian Randomization to Hypothesis Free Causal Inference

Wellcome Trust

Grant: unidentified

unidentified

FWCI

112.88

Citation Percentile

1.0%

Citation Trend

2018

2019

2020

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://wellcomeopenresearch.org/articles/4-186/v2/pdf

publisherhttps://wellcomeopenresearch.org/articles/4-186/v2/pdf

publisherhttps://wellcomeopenresearch.org/articles/4-186/v2/xml

publisherhttps://wellcomeopenresearch.org/articles/4-186/v2/iparadigms

journalhttps://doi.org/10.12688/wellcomeopenres.15555.2

Fields of Study

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestockGenetic Mapping and Diversity in Plants and Animals0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

Mendelian randomizationHarmonizationScope (computer science)Presentation (obstetrics)Computer sciencePsychologyMedicineBiologyGenetic variantsGeneticsgenetic epidemiologyguidelinescausal inference

Sustainable Development Goals

SDG 3: 3. Good health

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Additional file 1 of Breast cancer risk factors and their effects on survival: a Mendelian randomisation study

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Additional file 2 of Breast cancer risk factors and their effects on survival: a Mendelian randomisation study

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Additional file 2 of Breast cancer risk factors and their effects on survival: a Mendelian randomisation study

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Additional file 1 of Nonlinear causal effects of estimated glomerular filtration rate on myocardial infarction risks: Mendelian randomization study

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Additional file 1 of Exploring the causal role of the immune response to varicella-zoster virus on multiple traits: a phenome-wide Mendelian randomization study

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Additional file 3 of Exploring the causal role of the immune response to varicella-zoster virus on multiple traits: a phenome-wide Mendelian randomization study

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Additional file 3 of Exploring the causal role of the immune response to varicella-zoster virus on multiple traits: a phenome-wide Mendelian randomization study

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Additional file 1 of Cannabis use and atherosclerotic cardiovascular disease: a Mendelian randomization study

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Additional file 1 of Cannabis use and atherosclerotic cardiovascular disease: a Mendelian randomization study

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Additional file 2 of Cannabis use and atherosclerotic cardiovascular disease: a Mendelian randomization study

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Additional file 2 of Cannabis use and atherosclerotic cardiovascular disease: a Mendelian randomization study

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Additional file 1 of Elucidating the association of obstructive sleep apnea with brain structure and cognitive performance

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Additional file 1 of Elucidating the association of obstructive sleep apnea with brain structure and cognitive performance