George Davey Smith

Also affiliated with Medical Research Council

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

24.8Author DataRank

Indexed papers

13in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 13 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A road map for efficient and reliable human genome epidemiology

Nature Genetics(2006)10.1038/ng0106-3

Top 1%

10.4DataRank

Top 1%244 citations

John P. A. Ioannidis, Marta Gwinn, Julian Little, Julian P. T. Higgins, Jonine L. Bernstein +38 more

Papers

Driven by 133 papers — median percentile 74. Top paper: “A Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity”.

A Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity

Science(2007)10.1126/science.1141634

N/A

18.0DataRank · unranked

4497 citations

Nicholas J. Timpson, Michael N. Weedon, Eleftheria Zeggini, Rachel M. Freathy, Cecilia M. Lindgren +36 more

Guidelines for performing Mendelian randomization investigations

Wellcome Open Research(2020)10.12688/wellcomeopenres.15555.2

N/A

12.9DataRank · unranked

1353 citations

George Davey Smith, Neil M. Davies, Frank Dudbridge, Dipender Gill, M. Maria Glymour +6 more

Strengthening the reporting of observational studies in epidemiology using mendelian randomisation (STROBE-MR): explanation and elaboration

BMJ(2021)10.1136/bmj.n2233

N/A

12.0DataRank · unranked

1710 citations

Rebecca Richmond, Benjamin Woolf, Neil M. Davies, Sonja A. Swanson, Tyler J. VanderWeele +10 more

Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE Statement

Human Genetics(2009)10.1007/s00439-008-0592-7

N/A

11.0DataRank · unranked

188 citations

Julian P. T. Higgins, John P. A. Ioannidis, David Moher, France Gagnon, Erik von Elm +30 more

A road map for efficient and reliable human genome epidemiology

Nature Genetics(2006)10.1038/ng0106-3

Top 1%

10.4DataRank

Top 1%244 citations

John P. A. Ioannidis, Marta Gwinn, Julian Little, Julian P. T. Higgins, Jonine L. Bernstein +38 more

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

Nature Metabolism(2020)10.1038/s42255-020-00287-2

N/A

10.0DataRank · unranked

782 citations

Stefan Gustafsson, Qin Wang, Daniel Hvidberg Hansen, Åsa K. Hedman, Andrew J. Schork +78 more

Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel

Nature Communications(2015)10.1038/ncomms9111

Top 3%

6.7DataRank

Top 3%386 citations

Bryan Howie, Shane McCarthy, Yasin Memari, Klaudia Walter, Josine L. Min +234 more

Strengthening the reporting of genetic association studies (STREGA)—an extension of the strengthening the reporting of observational studies in epidemiology (STROBE) statement

Journal of Clinical Epidemiology(2009)10.1016/j.jclinepi.2008.12.004

N/A

6.0DataRank · unranked

102 citations

Julian P.T. Higgins, David Moher, France Gagnon, Erik von Elm, Muin J. Khoury +30 more

The Emergence of Networks in Human Genome Epidemiology

Epidemiology(2007)10.1097/01.ede.0000249540.17855.b7

N/A

4.3DataRank · unranked

92 citations

Muin J. Khoury, Thomas R. O??Brien, Julian Little, Julian P. T. Higgins, Jonine L. Bernstein +35 more

Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE statement

European Journal of Epidemiology(2009)10.1007/s10654-008-9302-y

N/A

4.3DataRank · unranked

65 citations

Julian P. T. Higgins, John P. A. Ioannidis, David Moher, France Gagnon, Erik von Elm +30 more

Genome-wide association study identifies 48 common genetic variants associated with handedness

Nature Human Behaviour(2020)10.1038/s41562-020-00956-y

N/A

3.7DataRank · unranked

157 citations

Joyce Y. Tung, Nicholas Eriksson, Eva Albrecht, Fazil Alıev, Ole A. Andreassen +95 more

Recommendations and proposed guidelines for assessing the cumulative evidence on joint effects of genes and environments on cancer occurrence in humans

International Journal of Epidemiology(2012)10.1093/ije/dys010

N/A

3.1DataRank · unranked

48 citations

Nick Wareham, D. C. Thomas, V. J. Cogliano, S. S. Hecht, D. Seminara +11 more

Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease

International Journal of Epidemiology(2021)10.1093/ije/dyab203

Top 7%

3.0DataRank

Top 7%122 citations

Yuemiao Zhang, Humaira Rasheed, Venexia Walker, Yuka Sugawara, Jiachen Li +38 more

Within-sibship GWAS improve estimates of direct genetic effects

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.05.433935

Top 10%

2.2DataRank

Top 10%75 citations

Michel G. Nivard, Tim Morris, Ailin Falkmo Hansen, Humaira Rasheed, Yoonsu Cho +83 more

The causes and consequences of Alzheimer’s disease: phenome-wide evidence from Mendelian randomization

Nature Communications(2022)10.1038/s41467-022-32183-6

N/A

1.9DataRank · unranked

68 citations

Laxmi Bhatta, Ben Brumpton, Laura D Howe, Louise A C Millard, Katarina Kolaric +7 more

Bias in meta-analysis detected by a simple, graphical test

BMJ(1997)10.1136/bmj.315.7109.629

N/A

1.6DataRank · unranked

55558 citations

George Davey Smith, Martin Schneider, Christoph Minder, C. Minder, Matthias Egger

Use of Correct and Incorrect Methods of Accounting for Age in Studies of Epigenetic Accelerated Aging: Implications and Recommendations for Best Practices

American Journal of Epidemiology(2023)10.1093/aje/kwad025

N/A

1.5DataRank · unranked

50 citations

Jarvis T. Chen, Christian Testa, Ana Diez Roux, Kate Tilling, Sarah Watkins +7 more

The relative contributions of obesity, vitamin D, leptin, and adiponectin to multiple sclerosis risk: A Mendelian randomization mediation analysis

Multiple Sclerosis Journal(2021)10.1177/1352458521995484

N/A

1.5DataRank · unranked

50 citations

Despoina Manousaki, Guillaume Butler‐Laporte, Ruth E. Mitchell, George Davey Smith, J. Brent Richards +2 more

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

Genetic Epidemiology(2016)10.1002/gepi.21965

N/A

1.4DataRank · unranked

9473 citations

George Davey Smith, Philip C Haycock, Stephen Burgess, Jack Bowden

The MR-Base platform supports systematic causal inference across the human phenome

eLife(2018)10.7554/elife.34408

N/A

1.4DataRank · unranked

8247 citations

Jie Zheng, Benjamin Elsworth, Kaitlin H Wade, Valeriia Haberland, Denis Baird +15 more

Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus

Nature Human Behaviour(2023)10.1038/s41562-023-01528-6

N/A

1.3DataRank · unranked

59 citations

Felix R. Day, Nicola Barban, Felix C. Tropf, David M. Brazel, Diana van Heemst +92 more

Sex Differences in the Risk of Coronary Heart Disease Associated With Type 2 Diabetes: A Mendelian Randomization Analysis

Diabetes Care(2020)10.2337/dc20-1137

N/A

1.3DataRank · unranked

33 citations

Michael V. Holmes, J. Brent Richards, Tom Palmer, Vincenzo Forgetta, Cecilia M. Lindgren +10 more

STrengthening the REporting of Genetic Association studies (STREGA)—an extension of the STROBE statement

Human Genome Epidemiology, 2nd Edition(2009)10.1093/acprof:oso/9780195398441.003.0010

N/A

1.1DataRank · unranked

7 citations

Julian P. T. Higgins, John P. A. Ioannidis, David Moher, France Gagnon, Erik von Elm +30 more

Impaired lung function and mortality risk in men and women: findings from the Renfrew and Paisley prospective population study

BMJ(1996)10.1136/bmj.313.7059.711

N/A

1.0DataRank · unranked

903 citations

G C M Watt, C L Hart, C R Gillis, V M Hawthorne, David Hole +5 more

Decline in attention-deficit hyperactivity disorder traits over the life course in the general population: trajectories across five population birth cohorts spanning ages 3 to 45 years

International Journal of Epidemiology(2022)10.1093/ije/dyac049

Top 20%

1.00DataRank

Top 20%30 citations

Lucy Riglin, Rachel Blakey, Jessica Agnew‐Blais, Arthur Caye, Tim Cadman +14 more

STrengthening the REporting of Genetic Association Studies (STREGA)— An Extension of the STROBE Statement

PLoS Medicine(2009)10.1371/journal.pmed.1000022

N/A

0.999DataRank · unranked

781 citations

Julian P.T. Higgins, David Moher, France Gagnon, Erik von Elm, Muin J. Khoury +31 more

STrengthening the REporting of Genetic Association Studies (STREGA)—an extension of the STROBE statement

Genetic Epidemiology(2009)10.1002/gepi.20410

N/A

0.874DataRank · unranked

339 citations

Julian P. T. Higgins, John P. A. Ioannidis, David Moher, France Gagnon, Erik von Elm +29 more

STrengthening the REporting of Genetic Association studies (STREGA) – an extension of the STROBE statement

European Journal of Clinical Investigation(2009)10.1111/j.1365-2362.2009.02125.x

N/A

0.868DataRank · unranked

326 citations

Julian P.T. Higgins, David Moher, France Gagnon, Erik von Elm, Muin J. Khoury +30 more

The use of negative control outcomes in Mendelian randomization to detect potential population stratification

International Journal of Epidemiology(2021)10.1093/ije/dyaa288

N/A

0.719DataRank · unranked

120 citations

Tom G. Richardson, Gibran Hemani, George Davey Smith, Eleanor Sanderson

Obesity Partially Mediates the Diabetogenic Effect of Lowering LDL Cholesterol

Diabetes Care(2021)10.2337/dc21-1284

N/A

0.700DataRank · unranked

26 citations

Jee‐Young Moon, Iyas Daghlas, Franco Giulianini, Bianca Porneala, Fariba Ahmadizar +47 more

Causal inference for heritable phenotypic risk factors using heterogeneous genetic instruments

PLoS Genetics(2021)10.1371/journal.pgen.1009575

N/A

0.692DataRank · unranked

100 citations

Qingyuan Zhao, Jack Bowden, Gibran Hemani, George Davey Smith, Dylan S. Small +2 more

Vitamin D levels and risk of type 1 diabetes: A Mendelian randomization study

PLOS Medicine(2021)10.1371/journal.pmed.1003536

N/A

0.683DataRank · unranked

94 citations

Adil Harroud, Ruth E. Mitchell, Stephanie Ross, Vincenzo Forgetta, Nicholas J. Timpson +4 more

Cross-trait analyses with migraine reveal widespread pleiotropy and suggest a vascular component to migraine headache

International Journal of Epidemiology(2020)10.1093/ije/dyaa050

N/A

0.665DataRank · unranked

83 citations

Derek Klarin, Scott M. Damrauer, Kyong-Mi Chang, Philip S. Tsao, Themistocles L. Assimes +93 more

Design and quality control of large-scale two-sample Mendelian randomization studies

International Journal of Epidemiology(2023)10.1093/ije/dyad018

Top 32%

0.620DataRank

Top 32%14 citations

Maria Carolina Borges, Kimberley Burrows, Rozenn N. Lemaître, Sean Harrison, Stephen Burgess +95 more

Principled distillation of UK Biobank phenotype data reveals underlying structure in human variation

Nature Human Behaviour(2024)10.1038/s41562-024-01909-5

N/A

0.564DataRank · unranked

18 citations

Rebecca Shafee, Robbee Wedow, Amanda Elliott, Duncan S. Palmer, John Compitello +14 more

Heritable confounding in Mendelian randomization studies

medRxiv10.1101/2024.09.05.24312293

N/A

0.478DataRank · unranked

13 citations

Dan Rosoff, Nicolai Vitt, Tom Palmer, Kate Tilling, George Davey Smith +2 more

Sex differences in cardiometabolic traits at four life stages: cohort study with repeated metabolomics

medRxiv(2020)10.1101/2020.01.15.19015206

Top 46%

0.398DataRank

Top 46%5 citations

Diana L. Santos Ferreira, Abigail Fraser, Ana Gonçalves Soares, Laura D Howe, Deborah A. Lawlor +4 more

Principled distillation of multidimensional UK Biobank data reveals insights into the correlated human phenome

medRxiv(2022)10.1101/2022.09.02.22279546

N/A

0.294DataRank · unranked

4 citations

Rebecca Shafee, Amanda Elliott, Duncan S. Palmer, John Compitello, Masahiro Kanai +14 more

The emergence of networks in human genome epidemiology: challenges and opportunities

Human Genome Epidemiology, 2nd Edition(2009)10.1093/acprof:oso/9780195398441.003.0007

Top 57%

0.276DataRank

Top 57%5 citations

Muin J. Khoury, Marta Gwinn, Julian Little, Julian P. T. Higgins, Jonine L. Bernstein +31 more

An epigenome-wide analysis of DNA methylation, racialized and economic inequities, and air pollution

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.07.570610

N/A

0.241DataRank · unranked

4 citations

Christian Testa, Andrew J. Simpkin, George Davey Smith, Brent A. Coull, Immaculata De Vivo +8 more

Strengthening the reporting of observational studies in epidemiology using Mendelian randomization (STROBE-MR): a Korean translation of explanation and elaboration

Ewha Medical Journal(2025)10.12771/emj.2025.00934

Top 70%

0.165DataRank

Top 70%2 citations

Rebecca Richmond, Benjamin Woolf, Neil M. Davies, Sonja A. Swanson, Tyler J. VanderWeele +10 more

The impact of low input DNA on the reliability of DNA methylation as measured by the Illumina Infinium MethylationEPIC BeadChip

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.22.473840

N/A

0.104DataRank · unranked

1 citations

Karen Ho, Christian Testa, Louise Falk, Patrice Soule, Linda V. Nguyen +12 more

Proteomics and Population Biology in the Cardiovascular Health Study (CHS): design of a study with mentored access and active data sharing

European Journal of Epidemiology(2022)10.1007/s10654-022-00888-z

N/A

0DataRank · unranked

28 citations

Caitlin McHugh, Jennifer A. Brody, Joshua C. Bis, Colleen M. Sitlani, Traci M. Bartz +33 more

Body Size at Different Ages and Risk of 6 Cancers: A Mendelian Randomization and Prospective Cohort Study

JNCI Journal of the National Cancer Institute(2022)10.1093/jnci/djac061

N/A

0DataRank · unranked

30 citations

Karl Smith-Byrne, Tom G. Richardson, Pietro Ferrari, Marc J. Gunter, Nikos Papadimitriou +31 more

The impact of fatty acids biosynthesis on the risk of cardiovascular diseases in Europeans and East Asians: a Mendelian randomization study

Human Molecular Genetics(2022)10.1093/hmg/ddac153

N/A

0DataRank · unranked

21 citations

Phillip Haycock, Jie Zheng, Gibran Hemani, Laurence J Howe, Amand F. Schmidt +10 more

Investigating the effect of sexual behaviour on oropharyngeal cancer risk: a methodological assessment of Mendelian randomization

BMC Medicine(2022)10.1186/s12916-022-02233-3

N/A

0DataRank · unranked

20 citations

Tom Dudding, Linda Kachuri, Kimberley Burrows, Amanda Chong, Richard M Martin +21 more

Separating the direct effects of traits on atherosclerotic cardiovascular disease from those mediated by type 2 diabetes

Diabetologia(2022)10.1007/s00125-022-05653-1

N/A

0DataRank · unranked

12 citations

Marijana Vujković, Alice R Carter, Neil M. Davies, Miriam S. Udler, Michael G. Levin +5 more

The impact of low input DNA on the reliability of DNA methylation as measured by the Illumina Infinium MethylationEPIC BeadChip

Epigenetics(2022)10.1080/15592294.2022.2123898

N/A

0DataRank · unranked

11 citations

Karen Ho, Christian Testa, Louise Falk, Patrice Soule, Linda V. Nguyen +12 more

Lowering of circulating sclerostin may increase risk of atherosclerosis and its risk factors: evidence from a genome-wide association meta-analysis followed by Mendelian randomization

medRxiv(2022)10.1101/2022.06.13.22275915

N/A

0DataRank · unranked

7 citations

Eleanor Wheeler, Maik Pietzner, Till F. M. Andlauer, Michelle S. Yau, April Hartley +32 more

Educational attainment, health outcomes and mortality: a within-sibship Mendelian randomization study

medRxiv(2022)10.1101/2022.01.11.22268884

N/A

0DataRank · unranked

6 citations

Humaira Rasheed, Paul Remy Jones, Dorret I. Boomsma, David M. Evans, Alexandros Giannelis +23 more

Genetically proxied PCSK9 inhibition provides indication of lower prostate cancer risk: a Mendelian randomization study

medRxiv(2022)10.1101/2022.04.18.22274003

N/A

0DataRank · unranked

2 citations

James Yarmolinsky, Dipender Gill, Caroline J. Bull, Claire M. Perks, George Davey Smith +3 more

Epigenetic clocks and research implications of the lack of data on whom they have been developed: a review of reported and missing sociodemographic characteristics

OSF Preprints (OSF Preprints)(2022)10.31219/osf.io/rj79d

N/A

0DataRank · unranked

2 citations

Christian Testa, Jarvis T. Chen, Immaculata De Vivo, Andrew J. Simpkin, Kate Tilling +7 more

Genetically-proxied impaired GIPR signalling and risk of 6 cancers

medRxiv(2022)10.1101/2022.08.06.22278459

N/A

0DataRank · unranked

0 citations

Dipender Gill, Emma Ahlqvist, Tim Robinson, Daniela Mariosa, Mattias Johansson +8 more

Guidelines for performing Mendelian randomization investigations: update for summer 2023

Wellcome Open Research(2023)10.12688/wellcomeopenres.15555.3

N/A

0DataRank · unranked

711 citations

George Davey Smith, Neil M. Davies, Frank Dudbridge, Dipender Gill, M. Maria Glymour +9 more

Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts

Cell Genomics(2023)10.1016/j.xgen.2022.100241

N/A

0DataRank · unranked

113 citations

Shinichi Namba, Esteban A. Lopera-Maya, Sini Kerminen, Kristin Tsuo, Kristi Läll +83 more

Multivariate genome-wide analysis of aging-related traits identifies novel loci and new drug targets for healthy aging

Nature Aging(2023)10.1038/s43587-023-00455-5

N/A

0DataRank · unranked

74 citations

Lucas A. Mavromatis, Andrew S. Bell, Josephin Wagner, Jeesun Jung, Riccardo E. Marioni +4 more

The association between genetically elevated polyunsaturated fatty acids and risk of cancer

EBioMedicine(2023)10.1016/j.ebiom.2023.104510

N/A

0DataRank · unranked

52 citations

Maria Carolina Borges, Kimberley Burrows, Rozenn N. Lemaître, Stephen Burgess, Nikhil K. Khankari +94 more

Lowering of Circulating Sclerostin May Increase Risk of Atherosclerosis and Its Risk Factors: Evidence From a Genome‐Wide Association Meta‐Analysis Followed by Mendelian Randomization

Arthritis & Rheumatology(2023)10.1002/art.42538

N/A

0DataRank · unranked

40 citations

Eleanor Wheeler, Maik Pietzner, Till F. M. Andlauer, Michelle S. Yau, April Hartley +32 more

Educational attainment, health outcomes and mortality: a within-sibship Mendelian randomization study

International Journal of Epidemiology(2023)10.1093/ije/dyad079

N/A

0DataRank · unranked

39 citations

Humaira Rasheed, Paul Remy Jones, Dorret I. Boomsma, David M. Evans, Alexandros Giannelis +42 more

Epigenetic clocks and research implications of the lack of data on whom they have been developed: a review of reported and missing sociodemographic characteristics

Current Zoology(2023)10.1093/eep/dvad005

N/A

0DataRank · unranked

31 citations

Christian Testa, Jarvis T. Chen, Immaculata De Vivo, Andrew J. Simpkin, Kate Tilling +7 more

Genome-wide association study of preserved ratio impaired spirometry (PRISm)

European Respiratory Journal(2023)10.1183/13993003.00337-2023

N/A

0DataRank · unranked

28 citations

Alvin Lirio, Fergus Hamilton, Raquel Granell, Annah B. Wyss, Stephanie J. London +40 more

The identification of distinct protective and susceptibility mechanisms for hip osteoarthritis: findings from a genome-wide association study meta-analysis of minimum joint space width and Mendelian randomisation cluster analyses

EBioMedicine(2023)10.1016/j.ebiom.2023.104759

N/A

0DataRank · unranked

26 citations

Monika Frysz, Cindy G. Boer, Daniel S. Evans, Raja Ebsim, Kaitlyn Flynn +17 more

Genetic evidence that high BMI in childhood has a protective effect on intermediate diabetes traits, including measures of insulin sensitivity and secretion, after accounting for BMI in adulthood

Diabetologia(2023)10.1007/s00125-023-05923-6

N/A

0DataRank · unranked

18 citations

Robin N. Beaumont, Jessica Tyrrell, Grace M. Power, Andrew R. Wood, Markku Laakso +7 more

Genetically proxied impaired GIPR signaling and risk of 6 cancers

iScience(2023)10.1016/j.isci.2023.106848

N/A

0DataRank · unranked

8 citations

Dipender Gill, Emma Ahlqvist, Tim Robinson, Daniela Mariosa, Mattias Johansson +8 more

Networks of Neurodevelopmental Traits, Socioenvironmental Factors, Emotional Dysregulation in Childhood, and Depressive Symptoms Across Development in Two U.K. Cohorts

American Journal of Psychiatry(2023)10.1176/appi.ajp.20220868

N/A

0DataRank · unranked

6 citations

Rachel Blakey, George Davey Smith, André Fujita, Elizabeth Shephard, Evie Stergiakouli +4 more

Association between circulating inflammatory markers and adult cancer risk: a Mendelian randomization analysis

medRxiv(2023)10.1101/2023.05.04.23289196

N/A

0DataRank · unranked

9 citations

Jamie Robinson, Daniela Mariosa, Ville Karhunen, Jian Huang, Niki Dimou +32 more

The mediating role of mammographic density in the protective effect of early-life adiposity on breast cancer risk: a multivariable Mendelian randomization study

medRxiv(2023)10.1101/2023.09.01.23294765

N/A

0DataRank · unranked

2 citations

George Davey Smith, Tom G. Richardson, Rebecca Richmond, Weiva Sieh, Joseph H. Rothstein +5 more

Genetic evidence that high BMI in childhood has a protective effect on intermediate diabetes traits, including measures of insulin sensitivity and secretion

medRxiv(2023)10.1101/2023.02.03.23285420

N/A

0DataRank · unranked

1 citations

Robin N. Beaumont, Jessica Tyrrell, Grace M. Power, Andrew R. Wood, Markku Laakso +7 more

Hip joint space width is causally related to hip osteoarthritis risk via distinct protective and susceptibility mechanisms: findings from a genome-wide association study meta-analysis

medRxiv(2023)10.1101/2023.03.01.23286618

N/A

0DataRank · unranked

0 citations

Benjamin G Faber, Cindy G. Boer, Daniel S. Evans, Raja Ebsim, Kaitlyn Flynn +17 more

Genomic insights into the comorbidity between type 2 diabetes and schizophrenia

medRxiv(2023)10.1101/2023.10.16.23297073

N/A

0DataRank · unranked

0 citations

Golam M. Khandaker, Andrew P. Morris, George Davey Smith, Laura M. Huckins, Eleftheria Zeggini +1 more

Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries

Nature Genetics(2024)10.1038/s41588-024-01951-z

N/A

0DataRank · unranked

22 citations

Adrián I. Campos, Santiago Díaz‐Torres, Jill A. Rabinowitz, Zuriel Ceja, Brittany L. Mitchell +95 more

Ancestry, ethnicity, and race: explaining inequalities in cardiometabolic disease

Trends in Molecular Medicine(2024)10.1016/j.molmed.2024.04.002

N/A

0DataRank · unranked

17 citations

Gibran Hemani, Sarah Watkins, Aylwyn Scally, George Davey Smith, Nish Chaturvedi +1 more

Mammographic density mediates the protective effect of early-life body size on breast cancer risk

Nature Communications(2024)10.1038/s41467-024-48105-7

N/A

0DataRank · unranked

18 citations

George Davey Smith, Tom G. Richardson, Rebecca Richmond, Weiva Sieh, Joseph H. Rothstein +5 more

Protein Identification for Stroke Progression via Mendelian Randomization in Million Veteran Program and UK Biobank

Stroke(2024)10.1161/strokeaha.124.047103

N/A

0DataRank · unranked

8 citations

Nimish Adhikari, April Hartley, Hugo J. Aparicio, Daniel Posner, Gibran Hemani +10 more

Multiomic Mendelian Randomization Study Investigating the Impact of PCSK9 and HMGCR Inhibition on Type 2 Diabetes Across Five Populations

Diabetes(2024)10.2337/db24-0451

N/A

0DataRank · unranked

8 citations

Josephin Wagner, Jeesun Jung, Pál Pacher, Constantinos Christodoulides, George Davey Smith +3 more

Genomic insights into the comorbidity between type 2 diabetes and schizophrenia

Schizophrenia(2024)10.1038/s41537-024-00445-5

N/A

0DataRank · unranked

5 citations

Golam M. Khandaker, Andrew P. Morris, George Davey Smith, Laura M. Huckins, Eleftheria Zeggini +1 more

Childhood adiposity underlies numerous adult brain traits commonly attributed to midlife obesity

Brain(2024)10.1093/brain/awae198

N/A

0DataRank · unranked

7 citations

Lydia Rader, Victoria Garfield, Isabelle F. Foote, Sana Suri, George Davey Smith +3 more

Evaluating the Cardiovascular Impact of Genetically Proxied PCSK9 and HMGCR Inhibition in East Asian and European Populations: A Drug-Target Mendelian Randomization Study

Circulation Genomic and Precision Medicine(2024)10.1161/circgen.122.004224

N/A

0DataRank · unranked

4 citations

Andrew S. Bell, Lucas A. Mavromatis, Ali Hamandi, Lauren M. Park, Jeesun Jung +6 more

Educational attainment and mental health conditions: a within-sibship Mendelian randomization study

medRxiv(2024)10.1101/2024.08.10.24311789

N/A

0DataRank · unranked

2 citations

Laxmi Bhatta, Paul Remy Jones, Martin Tesli, George Davey Smith, Neil M. Davies +3 more

Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease

Carolina Digital Repository (University of North Carolina at Chapel Hill)(2024)10.17615/w8ar-8g32

Top 100%

0DataRank

Top 100%0 citations

Rebecca Carnegie, K. Matsuda, A.P. Morris, Stephen Burgess, Jamie Robinson +38 more

Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies

Digital Commons@Becker (Washington University School of Medicine)(2024)10.17615/2bde-jk53

N/A

0DataRank · unranked

0 citations

A. Mahajan, Esteban J. Parra, Jeffrey Damman, Cecilia M. Lindgren, Johan Ärnlöv +67 more

Genomics and phenomics of body mass index reveals a complex disease network

RePEc: Research Papers in Economics(2024)10.17615/jxxp-qf89

N/A

0DataRank · unranked

0 citations

X. Mai Nguyen, Yan V. Sun, Ítalo Faria do Valle, Dan Rader, Julie A. Lynch +33 more

A multivariable Mendelian randomization analysis investigating smoking and alcohol consumption in oral and oropharyngeal cancer

UNC Libraries(2024)10.17615/9kmh-z010

N/A

0DataRank · unranked

0 citations

M. Pring, Marcus Robert Munafo, Samantha Thomas, Eleanor Sanderson, George Davey Smith +12 more

Mendelian Randomization and mediation analysis of leukocyte telomere length and risk of lung and head and neck cancers

UNC Libraries(2024)10.17615/g8tn-rh62

N/A

0DataRank · unranked

0 citations

Andy Ness, Matthew B. Schabath, Melinda C. Aldrich, H-Erich Wichmann, P. Lagiou +65 more

The effect of type 2 diabetes genetic predisposition on non-cardiovascular comorbidities

Nature Communications(2025)10.1038/s41467-025-64927-5

N/A

0DataRank · unranked

6 citations

Ozvan Bocher, Henry J. Taylor, Davis Cammann, Satoshi Yoshiji, Xianyong Yin +14 more

Prenatal maternal stress: triangulating evidence for intrauterine exposure effects on birth and early childhood outcomes across multiple approaches

BMC Medicine(2025)10.1186/s12916-024-03834-w

N/A

0DataRank · unranked

9 citations

Laurie J. Hannigan, Helga Ask, Adrian Dahl Askelund, Laura Hegemann, Elizabeth C. Corfield +7 more

Regular use of pharmaceutical opioids and subsequent risk of cancer: a prospective cohort study and Mendelian randomization analysis

EClinicalMedicine(2025)10.1016/j.eclinm.2025.103439

N/A

0DataRank · unranked

2 citations

Allison Domingues, Karine Alcala, Ryan Langdon, Daniela Mariosa, Xiaoshuang Feng +24 more

The effect of type 2 diabetes genetic predisposition on non-cardiovascular comorbidities

medRxiv(2025)10.1101/2025.05.05.25326966

N/A

0DataRank · unranked

0 citations

Ozvan Bocher, Henry J. Taylor, Davis Cammann, Satoshi Yoshiji, Xianyong Yin +13 more

African-specific genetic loci determine iron status and risk of severe malaria and bacteremia in African children

Research Square(2025)10.21203/rs.3.rs-6853969/v1

N/A

0DataRank · unranked

0 citations

Alexander J. Mentzer, Gavin Band, Amanda Y. Chong, Alex Macharia, Reagan M. Mogire +21 more

Education and cardiovascular disease: a within-family Mendelian randomisation analysis

medRxiv(2025)10.1101/2025.07.02.25330770

N/A

0DataRank · unranked

0 citations

Laxmi Bhatta, Laurence J Howe, María Fernanda Vinueza‐Veloz, Neil M Davies, George Davey Smith +3 more

Educational attainment and mental health outcomes: A within-sibship Mendelian randomization study

Psychological Medicine(2025)10.1017/s0033291725101736

N/A

0DataRank · unranked

0 citations

Laxmi Bhatta, Paul Remy Jones, Martin Tesli, George Davey Smith, Neil M. Davies +3 more

Protein identification for stroke progression via Mendelian Randomization in Million Veteran Program and UK Biobank

medRxiv(2024)10.1101/2024.01.31.24302111

N/A

0DataRank · unranked

1 citations

Nimish Adhikari, April Hartley, Hugo J. Aparicio, Dan C. Posner, Gibran Hemani +10 more

Lifecourse genome-wide association study meta-analysis refines the critical life stages for adiposity’s influence on breast cancer risk

Science Advances(2026)10.1126/sciadv.ady0374

N/A

0DataRank · unranked

0 citations

Laxmi Bhatta, Amanda M. Hughes, Carolina Medina‐Gómez, Anne Richmond, Genevieve M Leyden +18 more

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

UNC Libraries(2020)10.17615/2bje-6g29

N/A

0DataRank · unranked

0 citations

Deborah J. Thompson, Hannes Helgason, Timothy M. Frayling, Hilary K. Finucane, Patrick Sulem +211 more

Evaluating the relationship between alcohol consumption, tobacco use, and cardiovascular disease: A multivariable Mendelian randomization study

PLoS Medicine(2020)10.1371/journal.pmed.1003410

N/A

0DataRank · unranked

215 citations

George Davey Smith, Nehal N. Mehta, Toni‐Kim Clarke, Falk W. Lohoff, Daniel B. Rosoff

Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study

BMC Medicine(2020)10.1186/s12916-020-01855-9

N/A

0DataRank · unranked

179 citations

Joshua A. Bell, Neil Murphy, Eleanor Sanderson, George Davey Smith, Nicholas J. Timpson +73 more

Education, intelligence and Alzheimer’s disease: evidence from a multivariable two-sample Mendelian randomization study

International Journal of Epidemiology(2020)10.1093/ije/dyz280

N/A

0DataRank · unranked

155 citations

Laura D Howe, Kaitlin H Wade, Yoav Ben‐Shlomo, W. David Hill, Ian J. Deary +8 more

Genomic analysis of diet composition finds novel loci and associations with health and lifestyle

Molecular Psychiatry(2020)10.1038/s41380-020-0697-5

N/A

0DataRank · unranked

154 citations

Ronald de Vlaming, Peter N. Bowers, Casper A.P. Burik, Richard Karlsson Linnér, Chan Wook Lee +39 more

ADHD and depression: investigating a causal explanation

Psychological Medicine(2020)10.1017/s0033291720000665

N/A

0DataRank · unranked

147 citations

Beate Leppert, Christina Dardani, Ajay K. Thapar, Frances Rice, Michael C. O'Donovan +5 more

A multivariable Mendelian randomization analysis investigating smoking and alcohol consumption in oral and oropharyngeal cancer

Nature Communications(2020)10.1038/s41467-020-19822-6

N/A

0DataRank · unranked

143 citations

Tom Dudding, Eleanor Sanderson, Richard M Martin, Steven J. Thomas, Jessica Tyrrell +12 more

GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer

Nature Communications(2020)10.1038/s41467-020-17718-z

N/A

0DataRank · unranked

141 citations

Ben Brumpton, Ömer Kabil, Jūlı́us Guðmundsson, Guðmar Þorleifsson, Joshua S. Weinstock +51 more

Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses

Nature Communications(2020)10.1038/s41467-020-17117-4

N/A

0DataRank · unranked

423 citations

Eleanor Sanderson, Karl Heilbron, Fernando Pires Hartwig, Sean Harrison, Gunnhild Åberge Vie +28 more

Evaluating the cardiovascular safety of sclerostin inhibition using evidence from meta-analysis of clinical trials and human genetics

Science Translational Medicine(2020)10.1126/scitranslmed.aay6570

N/A

0DataRank · unranked

117 citations

Kristi Krebs, Chia‐Yen Chen, Ruth Boxall, Jenny C. Censin, Teresa Ferreira +15 more

Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort

Nature Communications(2020)10.1038/s41467-020-19257-z

N/A

0DataRank · unranked

95 citations

Ben Brumpton, Cristen J. Willer, Bjørn Olav Åsvold, Kåre I. Birkeland, Geng Wang +8 more

Dissecting maternal and fetal genetic effects underlying the associations between maternal phenotypes, birth outcomes, and adult phenotypes: A mendelian-randomization and haplotype-based genetic score analysis in 10,734 mother–infant pairs

PLoS Medicine(2020)10.1371/journal.pmed.1003305

N/A

0DataRank · unranked

91 citations

Jonas Bačelis, Pol Solé-Navais, Amit Kumar Srivastava, Julius Juodakis, Amy Rouse +13 more

Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility

Nature Communications(2020)10.1038/s41467-019-13855-2

N/A

0DataRank · unranked

45 citations

Mattias Johansson, Sara R. Rashkin, Rebecca E. Graff, Yohan Bossé, Venkata Manem +46 more

Educational attainment reduces the risk of suicide attempt among individuals with and without psychiatric disorders independent of cognition: a bidirectional and multivariable Mendelian randomization study with more than 815,000 participants

Translational Psychiatry(2020)10.1038/s41398-020-01047-2

N/A

0DataRank · unranked

52 citations

Zachary Kaminsky, Andrew M. McIntosh, George Davey Smith, Falk W. Lohoff, Daniel B. Rosoff

Genetic associations with temporal shifts in obesity and severe obesity during the obesity epidemic in Norway: A longitudinal population-based cohort (the HUNT Study)

PLoS Medicine(2020)10.1371/journal.pmed.1003452

N/A

0DataRank · unranked

19 citations

Johan Hå kon Bjø rngaard, Rønnaug Ødegård, Ben Brumpton, George Davey Smith, Bjørn Olav Åsvold +5 more

Genetic liability to schizophrenia is associated with exposure to traumatic events in childhood

Psychological Medicine(2020)10.1017/s0033291720000537

N/A

0DataRank · unranked

39 citations

Jazz Croft, Alexandra Havdahl, Hannah Jones, Erin C. Dunn, George Davey Smith +3 more

Pleiotropy of polygenic factors associated with focal and generalized epilepsy in the general population

PLoS ONE(2020)10.1371/journal.pone.0232292

N/A

0DataRank · unranked

28 citations

Tom G. Richardson, Tobias Kaufmann, Dennis van der Meer, Ole A. Andreassen, Lars T. Westlye +4 more

Assessment of a causal relationship between body mass index and atopic dermatitis

Journal of Allergy and Clinical Immunology(2020)10.1016/j.jaci.2020.04.050

N/A

0DataRank · unranked

26 citations

Sarah Watkins, Ben Brumpton, Mari Løset, Jessica Tyrrell, Ellen Heilmann Modalsli +10 more

Evaluating shared genetic influences on nonsyndromic cleft lip/palate and oropharyngeal neoplasms

Genetic Epidemiology(2020)10.1002/gepi.22343

N/A

0DataRank · unranked

7 citations

Gibran Hemani, Corina Lesseur, Valérie Gaborieau, Kerstin U. Ludwig, Elisabeth Mangold +6 more

Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study

medRxiv(2020)10.1101/2020.03.19.20031138

N/A

0DataRank · unranked

20 citations

Joshua A. Bell, Neil Murphy, Eleanor Sanderson, George Davey Smith, Nicholas J. Timpson +73 more

Unhealthy Behaviours and Parkinson’s Disease: A Mendelian Randomisation Study

medRxiv(2020)10.1101/2020.03.25.20039230

N/A

0DataRank · unranked

4 citations

Melanie P. Jensen, Sara Bandrés‐Ciga, Pierre Fontanillas, Cornelis Blauwendraat, Mike A. Nalls +5 more

Trans-ethnic Mendelian randomization study reveals causal relationships between cardio-metabolic factors and chronic kidney disease

medRxiv(2020)10.1101/2020.09.04.20188284

N/A

0DataRank · unranked

2 citations

YueMiao Zhang, Humaira Rasheed, Venexia Walker, Yuka Sugawara, Jiachen Li +38 more

Do maternal intrauterine environmental influences that lower offspring birthweight causally increase offspring cardiometabolic risk factors in later life? A Mendelian randomization study of 45,849 genotyped parent offspring pairs in the HUNT study

medRxiv(2020)10.1101/2020.05.04.20091173

N/A

0DataRank · unranked

1 citations

Ben Brumpton, Cristen J. Willer, Bjørn Olav Åsvold, Kåre I. Birkeland, Michael C. Neale +7 more

Using human genetics to understand the causes and consequences of circulating cardiac troponin I in the general population

medRxiv(2020)10.1101/2020.09.04.20187401

N/A

0DataRank · unranked

0 citations

Helge Røsjø, Anne Richmond, Magnus Nakrem Lyngbakken, Sarah E. Graham, Ailin Falkmo Hansen +22 more

Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents

UNC Libraries(2020)10.17615/gvf2-mw33

N/A

0DataRank · unranked

0 citations

Simon G. Thompson, Susan M. Gapstur, Eleni Sofi Anopoulou, Linda M. O’Keeffe, Jane Green +56 more

Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array

UNC Libraries(2020)10.17615/cjxw-ka66

N/A

0DataRank · unranked

0 citations

Ron C. Hoogeveen, Aaron R. Folsom, Brendan J. Keating, Andrew Johnson, Tom Palmer +17 more

Common variants near MC4R are associated with fat mass, weight and risk of obesity

UNC Libraries(2020)10.17615/wg5p-js22

N/A

0DataRank · unranked

0 citations

Murielle Bochud, Subhajyoti De, Christian Dina, Rachel M. Freathy, George Davey Smith +27 more

Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease

Journal of Human Genetics(2021)10.1038/s10038-020-00895-6

N/A

0DataRank · unranked

77 citations

Sean Bankier, Elisabeth Altmaier, Catriona L. K. Barnes, David W. Clark, Raili Ermel +36 more

Malaria is a cause of iron deficiency in African children

Nature Medicine(2021)10.1038/s41591-021-01238-4

N/A

0DataRank · unranked

64 citations

Alexander J. Mentzer, Ruth E. Mitchell, Emily L. Webb, Anthony Etyang, Catherine Kyobutungi +39 more

Unhealthy Behaviours and Risk of Parkinson’s Disease: A Mendelian Randomisation Study

Journal of Parkinson s Disease(2021)10.3233/jpd-202487

N/A

0DataRank · unranked

40 citations

Melanie P. Jensen, Sara Bandrés‐Ciga, Pierre Fontanillas, Cornelis Blauwendraat, Mike A. Nalls +5 more

Using genetic variants to evaluate the causal effect of cholesterol lowering on head and neck cancer risk: A Mendelian randomization study

PLoS Genetics(2021)10.1371/journal.pgen.1009525

N/A

0DataRank · unranked

31 citations

James Yarmolinsky, Tom Dudding, Kimberley Burrows, Richard M Martin, Steven J. Thomas +17 more

Genome-wide association study of cardiac troponin I in the general population

Human Molecular Genetics(2021)10.1093/hmg/ddab124

N/A

0DataRank · unranked

20 citations

Helge Røsjø, Anne Richmond, Magnus Nakrem Lyngbakken, Sarah E. Graham, Ailin Falkmo Hansen +25 more

A robust mean and variance test with application to high-dimensional phenotypes

European Journal of Epidemiology(2021)10.1007/s10654-021-00805-w

N/A

0DataRank · unranked

13 citations

Frank Windmeijer, Matthew Suderman, Matthew Lyon, George Davey Smith, Kate Tilling +1 more

Identifying molecular mediators of the relationship between body mass index and endometrial cancer risk: a Mendelian randomization analysis

medRxiv(2021)10.1101/2021.12.10.21267599

N/A

0DataRank · unranked

4 citations

Eleanor Sanderson, Vanessa Y Tan, Katherine S. Ruth, Timothy M. Frayling, Niki Dimou +10 more

Genetically-proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers

medRxiv(2021)10.1101/2021.03.11.21252971

N/A

0DataRank · unranked

2 citations

Virginia Díez‐Obrero, Tom G. Richardson, Marie Pigeyre, Jennifer Sjaarda, Guillaume Paré +19 more

Genomics and phenomics of body mass index reveals a complex disease network

Nature Communications(2022)10.1038/s41467-022-35553-2

N/A

0DataRank · unranked

188 citations

Jennifer E. Huffman, Yunfeng Huang, Ítalo Faria do Valle, Themistocles L. Assimes, Sridharan Raghavan +34 more

Blood pressure-lowering treatment for prevention of major cardiovascular diseases in people with and without type 2 diabetes: an individual participant-level data meta-analysis

The Lancet Diabetes & Endocrinology(2022)10.1016/s2213-8587(22)00172-3

N/A

0DataRank · unranked

104 citations

Zeinab Bidel, Dexter Canoy, Emma Copland, Derrick Bennett, Abbas Dehghan +95 more

Meta-analysis fine-mapping is often miscalibrated at single-variant resolution

Cell Genomics(2022)10.1016/j.xgen.2022.100210

N/A

0DataRank · unranked

85 citations

Roy Elzur, Wei Zhou, Kuan-Han Wu, Humaira Rasheed, Kristin Tsuo +91 more

Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study

eLife(2022)10.7554/elife.75374

N/A

0DataRank · unranked

84 citations

Daniel L McCartney, Ake T Lu, Konstantinos K Tsilidis, Emmanouil Bouras, Philip C Haycock +12 more

Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers: A mendelian randomization analysis

PLoS Medicine(2022)10.1371/journal.pmed.1003897

N/A

0DataRank · unranked

69 citations

Virginia Díez‐Obrero, Tom G. Richardson, Marie Pigeyre, Jennifer Sjaarda, Guillaume Paré +18 more

George Davey Smith

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