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MYCN drives oncogenesis by cooperating with the histone methyltransferase G9a and the WDR5 adaptor to orchestrate global gene transcription

PLoS Biology(2024)10.1371/journal.pbio.3002240Source: DataRank Database

MYCN drives oncogenesis by cooperating with the histone methyltransferase G9a and the WDR5 adaptor to orchestrate global gene transcription is a research paper published in PLoS Biology (2024). On theSindex it has a DataRank of 0. It has been cited 12 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access12 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)Impact (FWCI 3.51)OA: goldTopics (42)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Xiyuan Zhang ORCID,Man Xu ORCID,Jason J Hong ORCID,Amanda Ciardiello ORCID,Haiyan Lei ORCID

Live enrichment

PubMed:38547242 PMC:PMC11003700 OpenAlex:https://openalex.org/W4393253559

National Cancer Institute

Grant: Z01:ZIA BC 010788

Intramural NIH HHS

Grant: ZIA BC010788

National Institutes of Health

Grant: 1ZIABC010788-08

Regulation of Differentiation of Pediatric Embryonal Tumors- Neuroblastoma

FWCI

3.51

Citation Percentile

0.9%

Citation Trend

2024

2025

2026

goldLicense: cc-by

journalhttps://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002240&type=printable

publisherhttps://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002240&type=printable

publisherhttps://dx.plos.org/10.1371/journal.pbio.3002240

journalhttps://doi.org/10.1371/journal.pbio.3002240

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38547242

Fields of Study

Neuroblastoma Research and TreatmentsProtein Degradation and InhibitorsUbiquitin and proteasome pathways0301 basic medicine03 medical and health sciences

MeSH Terms

N-Myc Proto-Oncogene ProteinHistone MethyltransferasesCell Transformation, NeoplasticHumansNuclear ProteinsTranscription, GeneticGene Expression Regulation, NeoplasticCell Line, TumorIntracellular Signaling Peptides and ProteinsCarcinogenesis

Keywords

BiologyEnhancerPromoterRibosome biogenesisTranscription factorGeneticsH3K4me3GeneCarcinogenesisRegulation of gene expressionCell biologyCancer researchGene expressionRibosomeRNAN-Myc Proto-Oncogene ProteinTranscription, GeneticQH301-705.5Intracellular Signaling Peptides and ProteinsNuclear ProteinsGene Expression Regulation, NeoplasticCell Transformation, NeoplasticCell Line, TumorHistone MethyltransferasesHumansBiology (General)Research Article