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Simple scaling laws control the genetic architectures of human complex traits

PLoS Biology(2025)10.1371/journal.pbio.3003402Source: DataRank Database

Simple scaling laws control the genetic architectures of human complex traits is a research paper published in PLoS Biology (2025). On theSindex it has a DataRank of 0. It has been cited 12 times.

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Open Access12 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (4 grants)Impact (FWCI 13.54)OA: goldTopics (24)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Hakhamanesh Mostafavi ORCID,Huisheng Zhu,Courtney J. Smith ORCID,Jonathan K. Pritchard ORCID,Guy Sella ORCID

Live enrichment

PubMed:41082512 PMC:PMC12517483 OpenAlex:https://openalex.org/W4415108395

NIH

Grant: R01 HG008140

NIH

Grant: R01 HG011432

NIH

Grant: R01 GM115889

NIH

Grant: F32 HG011202

FWCI

13.54

Citation Percentile

1.0%

Citation Trend

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.1371/journal.pbio.3003402

publisherhttps://doi.org/10.1371/journal.pbio.3003402

publisherhttps://dx.plos.org/10.1371/journal.pbio.3003402

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41082512

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/12517483

Fields of Study

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and AnimalsGenetic and phenotypic traits in livestock

MeSH Terms

Gene FrequencyHumansModels, GeneticMutationPhenotypeSelection, GeneticQuantitative Trait, HeritableMultifactorial InheritanceQuantitative Trait LociGenetic DriftGenome-Wide Association Study

Keywords

Genetic architectureSelection (genetic algorithm)HeritabilityTraitQuantitative trait locusScalingPolygeneSimilarity (geometry)Adaptation (eye)Quantitative genetics

Simple scaling laws control the genetic architectures of human complex traits

FAIR Checklist

Authors (6)

Funding (4 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)