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In Silico Elucidation of the Molecular Mechanism Defining the Adverse Effect of Selective Estrogen Receptor Modulators

PLoS Computational Biology(2007)10.1371/journal.pcbi.0030217Source: DataRank Database

In Silico Elucidation of the Molecular Mechanism Defining the Adverse Effect of Selective Estrogen Receptor Modulators is a research paper published in PLoS Computational Biology (2007). On theSindex it has a DataRank of 4.0. It has been cited 83 times, with 63 citing works in its 1-hop citation network.

N/A

4.0DataRank · unranked

Scored on demand from live citation data

Open Access83 citations · 63 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (2 grants)Impact (FWCI 8.32)OA: goldTopics (50)IDs (PubMed, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 17%Citation Network 83%

Base Score Contribution

0.665

From this paper's citation signal

Citation Network Contribution

3.3

From 63 citing papers with measurable signal

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Authors (3)

Jian Wang ORCID,Philip E. Bourne ORCID,Lei Xie ORCID

Live enrichment

PubMed:18052534 OpenAlex:https://openalex.org/W1985755631

National Institutes of Health

Grant: 5R01GM078596-03

Protein Functional Site Characterization and Analysis

National Institutes of Health

Grant: 5P01GM063208-04

Alignment algorithms applied to protein fold and remote homologue recognition

FWCI

8.32

Citation Percentile

1.0%

Citation Trend

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goldLicense: cc-by

journalhttps://doi.org/10.1371/journal.pcbi.0030217

publisherhttps://doi.org/10.1371/journal.pcbi.0030217

publisherhttps://dx.plos.org/10.1371/journal.pcbi.0030217

repositoryhttps://pubmed.ncbi.nlm.nih.gov/18052534

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/2098847

Fields of Study

Computational Drug Discovery MethodsEstrogen and related hormone effectsSteroid Chemistry and Biochemistry0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Amino Acid SequenceBinding SitesComputer SimulationModels, ChemicalModels, MolecularMolecular Sequence DataProtein BindingProtein ConformationReceptors, EstrogenStructure-Activity RelationshipToxicity TestsSequence Analysis, ProteinSelective Estrogen Receptor ModulatorsProtein Interaction Mapping

Keywords

In silicoMechanism (biology)Computational biologySelective estrogen receptor modulatorEstrogen receptorBioinformaticsEstrogen receptor alphaChemistryPharmacologyBiologyBiochemistryGeneticsGeneModels, MolecularSelective Estrogen Receptor ModulatorsBinding SitesQH301-705.5Protein ConformationMolecular Sequence DataStructure-Activity RelationshipModels, ChemicalReceptors, EstrogenSequence Analysis, ProteinProtein Interaction MappingToxicity TestsComputer SimulationAmino Acid SequenceBiology (General)Research ArticleProtein Binding

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being