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Mechanistic models of PLC/PKC signaling implicate phosphatidic acid as a key amplifier of chemotactic gradient sensing

PLoS Computational Biology(2020)10.1371/journal.pcbi.1007708Source: DataRank Database

Mechanistic models of PLC/PKC signaling implicate phosphatidic acid as a key amplifier of chemotactic gradient sensing is a research paper published in PLoS Computational Biology (2020). On theSindex it has a DataRank of 0. It has been cited 8 times.

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Open Access8 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)Impact (FWCI 0.44)OA: goldTopics (69)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (6)

Anisur Rahman ORCID,Krithika Mohan,Timothy C. Elston ORCID,James E. Bear ORCID,Jason M. Haugh ORCID

Live enrichment

PubMed:32255775 PMC:PMC7164671 OpenAlex:https://openalex.org/W3014236556

National Institute of Biomedical Imaging and Bioengineering

Grant: U01-EB018816

NIGMS NIH HHS

Grant: R24 GM134211

NIBIB NIH HHS

Grant: U01 EB018816

NCI NIH HHS

Grant: P30 CA016086

National Institutes of Health

Grant: 1U01EB018816-01

Multiscale Modeling of Wound Healing

National Institutes of Health

Grant: 1R24GM134211-01

The Virtual Cell: a Computational Resource for Collaborative Modeling and Simulation of Cell Biology

FWCI

0.44

Citation Percentile

0.6%

Citation Trend

2022

2024

2025

goldLicense: cc-by

journalhttps://doi.org/10.1371/journal.pcbi.1007708

publisherhttps://doi.org/10.1371/journal.pcbi.1007708

publisherhttps://dx.plos.org/10.1371/journal.pcbi.1007708

repositoryhttps://pubmed.ncbi.nlm.nih.gov/32255775

repositoryhttps://doaj.org/article/38c879e4765f4fdea7a92e4d6401cb93

Fields of Study

Cellular Mechanics and Interactions3D Printing in Biomedical ResearchCancer Cells and Metastasis0301 basic medicine03 medical and health sciencesAnimalsChemotaxisDiglyceridesFibroblastsHumansIntracellular Signaling Peptides and ProteinsMembrane ProteinsModels, TheoreticalMyristoylated Alanine-Rich C Kinase SubstratePhosphatidic AcidsPhospholipase DPhosphorylationPlatelet-Derived Growth FactorProtein Kinase CSignal TransductionType C Phospholipases

MeSH Terms

Myristoylated Alanine-Rich C Kinase SubstrateAnimalsChemotaxisDiglyceridesFibroblastsHumansMembrane ProteinsModels, TheoreticalPhosphatidic AcidsType C PhospholipasesPhospholipase DPhosphorylationPlatelet-Derived Growth FactorProtein Kinase CSignal TransductionIntracellular Signaling Peptides and Proteins

Keywords

ChemotaxisProtein kinase CCell biologyPhosphatidic acidLysophosphatidic acidPhospholipase DDiacylglycerol kinasePhospholipase CBiologySignal transductionAutocrine signallingMARCKSKinaseChemistryBiochemistryReceptorPhospholipidPlatelet-Derived Growth FactorQH301-705.5Intracellular Signaling Peptides and ProteinsMembrane ProteinsPhosphatidic AcidsFibroblastsModels, TheoreticalDiglyceridesType C PhospholipasesAnimalsHumansBiology (General)PhosphorylationMyristoylated Alanine-Rich C Kinase SubstrateResearch Article

Sustainable Development Goals

SDG 0: Life below water