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Glucocerebrosidase deficiency leads to neuropathology via cellular immune activation

PLoS Genetics(2024)10.1371/journal.pgen.1011105Source: DataRank Database

Glucocerebrosidase deficiency leads to neuropathology via cellular immune activation is a research paper published in PLoS Genetics (2024). On theSindex it has a DataRank of 0. It has been cited 6 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access6 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 1.38)OA: goldTopics (59)IDs (PubMed, PMC, OpenAlex)Annotations (3)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Ruth E. Thomas ORCID,Gillian Milstein ORCID,Gautam Pareek ORCID,Theo K. Bammler,James W. MacDonald ORCID

Live enrichment

PubMed:39527642 PMC:PMC11581407 OpenAlex:https://openalex.org/W4404238221

National Institute of Neurological Disorders and Stroke

Grant: R01AG075100

National Institute of Neurological Disorders and Stroke

Grant: R21AG068356

National Institutes of Health

Grant: 5R01AG075100-02

Mechanism of innate immune activation in a Drosophila model of Alzheimer's disease related dementia

National Institutes of Health

Grant: 5R21AG068356-02

Mechanism and importance of innate immune activation in a Drosophila GBA mutant model of Parkinson's disease

National Institutes of Health

Grant: 1R01AG075100-01

Mechanism of innate immune activation in a Drosophila model of Alzheimer's disease related dementia

FWCI

1.38

Citation Percentile

0.8%

Citation Trend

2025

2026

goldLicense: cc-by

journalhttps://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1011105&type=printable

GOLDhttps://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1011105&type=printable

publisherhttps://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1011105&type=printable

publisherhttps://dx.plos.org/10.1371/journal.pgen.1011105

journalhttps://doi.org/10.1371/journal.pgen.1011105

Fields of Study

Zebrafish Biomedical Research ApplicationsLysosomal Storage Disorders ResearchInvertebrate Immune Response MechanismsMedicineBiology03 medical and health sciences0302 clinical medicineGlucosylceramidaseAnimalsMacrophage ActivationDisease Models, AnimalMutationDrosophila melanogasterMacrophagesGlucosylceramidesParkinson DiseaseHumansDrosophila ProteinsImmunity, CellularDrosophila

MeSH Terms

AnimalsDisease Models, AnimalDrosophilaDrosophila melanogasterGlucosylceramidaseGlucosylceramidesHumansImmunity, CellularMacrophage ActivationMacrophagesMutationParkinson DiseaseDrosophila Proteins

Keywords

GlucocerebrosidaseNeuropathologyBiologyImmune systemCell biologyImmunologyNeuroscienceGeneticsDiseasePathologyImmunity, CellularMacrophagesParkinson DiseaseQH426-470Macrophage ActivationGlucosylceramidesArticleDisease Models, AnimalDrosophila melanogasterMutationGlucosylceramidaseAnimalsHumansDrosophila ProteinsDrosophilaResearch Article

Sustainable Development Goals

SDG 3: 3. Good health