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Patient stratification by genetic risk in Alzheimer’s disease is only effective in the presence of phenotypic heterogeneity

PLoS ONE(2025)10.1371/journal.pone.0310977Source: DataRank Database

Patient stratification by genetic risk in Alzheimer’s disease is only effective in the presence of phenotypic heterogeneity is a research paper published in PLoS ONE (2025). On theSindex it has a DataRank of 0. It has been cited 4 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access4 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (20 grants)OA: goldTopics (58)IDs (PubMed, PMC)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Muhammad Ali ORCID,Chloe Robins ORCID,Praveen Surendran ORCID,Padhraig Gormley ORCID,for the Alzheimer’s Disease Neuroimaging Initiative (ADNI)

Live enrichment

PubMed:39787209 PMC:PMC11717250

Foundation for the National Institutes of Health

Grant: RF1AG074007

Foundation for the National Institutes of Health

Grant: R01AG044546

Foundation for the National Institutes of Health

Grant: P01AG003991

Foundation for the National Institutes of Health

Grant: RF1AG053303

Foundation for the National Institutes of Health

Grant: RF1AG058501

Foundation for the National Institutes of Health

Grant: U01AG058922

Foundation for the National Institutes of Health

Grant: P30AG066444

Foundation for the National Institutes of Health

Grant: P01AG03991

Foundation for the National Institutes of Health

Grant: P01AG026276

NIA NIH HHS

Grant: R01 AG058501

National Institutes of Health

Grant: 1P30AG066444-01

Alzheimer's Disease Research Center

National Institutes of Health

Grant: 1R13AG013039-01

1995 SUMMER INSTITUTE IN GERIATRIC MEDICINE

National Institutes of Health

Grant: 5R01AG044546-03

IDENTIFYING RARE VARIANTS THAT INCREASE RISK FOR ALZHEIMER'S DISEASE

National Institutes of Health

Grant: 1RF1AG074007-01

Sex-specific Molecular Profiling to Understand Pathology and Identify Causal Genes and Drug Targets for Alzheimer's Disease

National Institutes of Health

Grant: 1RF1AG058501-01

GENETIC MODIFIERS OF CEREBROSPINAL FLUID TREM2 IN ALZHEIMER'S DISEASE

National Institutes of Health

Grant: 5P01AG003991-38

Healthy Aging and Senile Dementia

National Institutes of Health

Grant: 3RF1AG053303-01S1

USING QUANTITATIVE TRAITS TO IDENTIFY NOVEL GENES FOR ALZHEIMERS DISEASE AND OTHER COMPLEX TRAITS

National Institutes of Health

Grant: 5U01AG058922-05

The Familial Alzheimer Sequencing (FASe) Project

National Institutes of Health

Grant: 5P01AG026276-07

Antecedent Neuroimaging Biomarkers

Chan Zuckerberg Initiative

goldLicense: cc-by

publisherhttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0310977&type=printable

publisherhttps://dx.plos.org/10.1371/journal.pone.0310977

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11717250/pdf/pone.0310977.pdf

repositoryhttps://digitalcommons.wustl.edu/oa_4/4837

repositoryhttps://doaj.org/article/fe99ff4d952f4876a20c270400ddf341

Fields of Study

0301 basic medicine03 medical and health sciencesAlzheimer DiseaseHumansGenome-Wide Association StudyFemaleMaleGenetic Predisposition to DiseaseAgedMendelian Randomization AnalysisPhenotypeDisease ProgressionMultifactorial InheritanceRisk FactorsPolymorphism, Single NucleotideAged, 80 and overApolipoprotein E4

MeSH Terms

HumansAlzheimer DiseaseDisease ProgressionGenetic Predisposition to DiseaseRisk FactorsMultifactorial InheritancePhenotypePolymorphism, Single NucleotideAgedAged, 80 and overFemaleMaleApolipoprotein E4Genome-Wide Association StudyMendelian Randomization Analysis

Keywords

MaleMultifactorial InheritanceScienceApolipoprotein E4610Polymorphism, Single NucleotideAlzheimer DiseaseRisk Factors80 and overMedicine and Health SciencesHumansGenetic Predisposition to DiseasePolymorphismAgedAged, 80 and overQICTS (Institute of Clinical and Translational Sciences)RSingle NucleotideMendelian Randomization AnalysisPhenotypeDisease ProgressionMedicineFemaleResearch ArticleGenome-Wide Association Study