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VX-809 corrects folding defects in cystic fibrosis transmembrane conductance regulator protein through action on membrane-spanning domain 1

UNC Libraries(2020)10.17615/5pzy-8d07Source: DataRank Database

VX-809 corrects folding defects in cystic fibrosis transmembrane conductance regulator protein through action on membrane-spanning domain 1 is a research paper published in UNC Libraries (2020). On theSindex it has a DataRank of 0. It has been cited 1 time.

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0DataRank · unranked

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Open Access1 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (2 grants)OA: greenTopics (37)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Scott A. Houck,Douglas Cyr ORCID,Fredrick Van Goor,Oxana De La Rosa,Beth J. Hoffman

Live enrichment

PubMed:21097893 OpenAlex:https://openalex.org/W4298279942

National Institutes of Health

Grant: 7R01GM056981-05

CHAPERONES AND THE BIOGENESIS OF MEMBRANE PROTEINS

National Institutes of Health

Grant: 5R01GM067785-08

Hsp40 and conformational disease

greenLicense: CC BY NC SA

repositoryhttps://doi.org/10.17615/5pzy-8d07

https://doi.org/10.1091/mbc.e13-05-0240

https://dx.doi.org/10.17615/5pzy-8d07

https://pubmed.ncbi.nlm.nih.gov/23924900

http://dx.doi.org/10.1091/mbc.E13-05-0240

Fields of Study

Cystic Fibrosis Research Advances0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

Cystic fibrosis transmembrane conductance regulatorConductanceFolding (DSP implementation)Transmembrane proteinRegulatorBiophysicsCystic fibrosisDomain (mathematical analysis)Action (physics)Transmembrane domainChemistryMembrane proteinMembraneCell biologyPhysicsMedicineBiologyInternal medicineBiochemistryCondensed matter physicsEngineeringMathematicsMathematical analysisReceptorProtein FoldingProtein ConformationMutation, MissenseAminopyridinesArticlesProtein Structure, TertiaryHumansBenzodioxolesSignal Transduction

Sustainable Development Goals

SDG 3: 3. Good health