VCP/p97, a pleiotropic protein regulator of the DNA damage response and proteostasis, is a potential therapeutic target in KRAS-mutant pancreatic cancer is a research paper published in UNC Libraries (2025). On theSindex it has a DataRank of 0.
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National Institutes of Health
Grant: 3U01CA199235-04S1
Identification of synthetic lethal interactors in pancreatic cancer
National Institutes of Health
Grant: 5T32CA009156-20
BASIC MECHANISMS OF VIRAL AND CHEMICAL CARCINOGENESIS
National Institutes of Health
Grant: 5T32GM007040-35
Predoctoral Training in Pharmacological Sciences
National Institutes of Health
Grant: 1T32GM135095-01
Predoctoral Training in the Pharmacological Sciences
National Institutes of Health
Grant: 5T32GM135128-05
NRSA in Genetics
National Institutes of Health
Grant: 5R01ES029079-03
Pathological Reprogramming of DNA Damage Signaling in Neoplastic Cells
National Institutes of Health
Grant: 5R35CA232113-04
Targeting undruggable RAS for cancer treatment
National Institutes of Health
Grant: 5R01CA042978-26
Biological Activity of Ras Oncogenes
National Institutes of Health
Grant: 1F32CA221005-01
Targeting CDK4/6 for pancreatic cancer treatment
National Institutes of Health
Grant: 5R01CA175747-05
Mechanisms of PAK1 activation, signaling and tumor resistance
National Institutes of Health
Grant: 1F32CA239328-01
Defining the roles of ERK MAPK in driving KRAS-mutant pancreatic cancer growth.
National Institutes of Health
Grant: 5P01CA203657-02
Defining RAS isoform- and mutation-specific roles in oncogenesis
National Institutes of Health
Grant: 5R37CA251877-02
Mechanistic dissection and inhibitor targeting of autophagy in RAS driven cancers
National Institutes of Health
Grant: 5F32CA232529-03
Defining the contributions of WT RAS in RAS-mutant lung cancer
National Institutes of Health
Grant: 5R01CA229530-04
Establishing MAGE-A4/RAD18 as a novel cancer-specific chemotherapeutic target
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Sustainable Development Goals