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Mutating for Good: DNA Damage Responses During Somatic Hypermutation

Frontiers in Immunology(2019)10.3389/fimmu.2019.00438Source: DataRank Database

Mutating for Good: DNA Damage Responses During Somatic Hypermutation is a research paper published in Frontiers in Immunology (2019). On theSindex it has a DataRank of 2.8. It has been cited 112 times, with 104 citing works in its 1-hop citation network.

N/A

2.8DataRank · unranked

Scored on demand from live citation data

112 citations · 104 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 4.65)OA: goldTopics (39)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (0/2)

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 25%Citation Network 75%

Base Score Contribution

0.709

From this paper's citation signal

Citation Network Contribution

2.1

From 87 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 104 citers.

Learning the heterogeneous hypermutation landscape of immunoglobulins from high-throughput repertoire data
Nucleic Acids Research202049 citations41 referencesContributes 0.095
Blood transcriptome profile induced by an efficacious vaccine formulated with salivary antigens from cattle ticks
npj Vaccines201924 citations37 referencesContributes 0.087
AID Overlapping and Polη Hotspots Are Key Features of Evolutionary Variation Within the Human Antibody Heavy Chain (IGHV) Genes
Frontiers in Immunology202038 citations43 referencesContributes 0.085
Evaluation of Somatic Hypermutation Status in Chronic Lymphocytic Leukemia (CLL) in the Era of Next Generation Sequencing
Frontiers in Cell and Developmental Biology202021 citations45 referencesContributes 0.069
Deep learning model of somatic hypermutation reveals importance of sequence context beyond hotspot targeting
iScience202130 citations50 referencesContributes 0.069

Authors (2)

Heinz Jacobs ORCID,Bas Pilzecker

Live enrichment

PubMed:30915081 PMC:PMC6423074 OpenAlex:https://openalex.org/W2920915242

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Grant: ZonMW Top 91213018

KWF Kankerbestrijding

Grant: KWF NKI-2012–5243

KWF Kankerbestrijding

Grant: KWF NKI-2016-10032

KWF Kankerbestrijding

Grant: KWF NKI-2016-10796

ZonMw

Grant: 91213018

FWCI

4.65

Citation Percentile

1.0%

Citation Trend

2019

2020

2021

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://www.frontiersin.org/articles/10.3389/fimmu.2019.00438/pdf

publisherhttps://www.frontiersin.org/articles/10.3389/fimmu.2019.00438/pdf

publisherhttps://www.frontiersin.org/article/10.3389/fimmu.2019.00438/full

journalhttps://doi.org/10.3389/fimmu.2019.00438

repositoryhttps://pubmed.ncbi.nlm.nih.gov/30915081

Fields of Study

DNA Repair MechanismsCarcinogens and Genotoxicity AssessmentAcute Lymphoblastic Leukemia researchB-LymphocytesCytidine DeaminaseDNADNA DamageDNA RepairDeaminationHumansSomatic Hypermutation, ImmunoglobulinVDJ ExonsAICDA (Activation-Induced Cytidine Deaminase)

MeSH Terms

AICDA (Activation-Induced Cytidine Deaminase)B-LymphocytesCytidine DeaminaseDeaminationDNADNA DamageDNA RepairHumansSomatic Hypermutation, ImmunoglobulinVDJ Exons

Keywords

Somatic hypermutationSomatic cellGeneticsBiologyDNA damageMutationDNAAntibodyB cellGeneBase Excision RepairAbasic SiteDna Damage Tolerance (Ddt)Translesion Synthesis (Tls)Cytosine DeaminationNon-canonical Mismatch Repair (Ncmmr)

Sustainable Development Goals

SDG 0: Peace, Justice and strong institutions

Related Papers (2)

Mesoscale DNA feature in antibody-coding sequence facilitates somatic hypermutation

N/A

1.0DataRank · unranked

Cell(2023)

co-cited

10.1016/j.cell.2023.03.030

DNA polymerase zeta contributes to heterochromatin replication to prevent genome instability

N/A

1.1DataRank · unranked

The EMBO Journal(2021)

co-cited

10.15252/embj.2020104543

Mutating for Good: DNA Damage Responses During Somatic Hypermutation

FAIR Checklist

DataRank Breakdown

Top 5 citers driving the network score

Authors (2)

Funding (5 grants)

Impact

Open Access

Topics

Related Papers (2)