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NLRP3 Inflammasome Assembly in Neutrophils Is Supported by PAD4 and Promotes NETosis Under Sterile Conditions

Frontiers in Immunology(2021)10.3389/fimmu.2021.683803Source: DataRank Database

NLRP3 Inflammasome Assembly in Neutrophils Is Supported by PAD4 and Promotes NETosis Under Sterile Conditions is a research paper published in Frontiers in Immunology (2021). On theSindex it has a DataRank of 0. It has been cited 175 times.

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Open Access175 citations

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Enrichment:Funding (4 grants)OA: goldTopics (40)IDs (PubMed, PMC)SDGs (2)

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Open Access

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Authors (16)

Roberto Negro ORCID,Shoichi Fukui ORCID,Lucas Di Meglio ORCID,Karen Aymonnier ORCID,Long Chu ORCID

Live enrichment

PubMed:34122445 PMC:PMC8195330

NIAID NIH HHS

Grant: R01 AI124491

NHLBI NIH HHS

Grant: R35 HL135765

European Commission

Grant: 796365

CK2-dependent cytoskeletal regulation and molecular signaling of Neutrophil Extracellular Trap (NET) formation

National Institutes of Health

Grant: 5R35HL135765-03

How inflammation and thrombosis fuel disease and aging: Focus on NETs

goldLicense: CC BY

Europe_PMChttps://europepmc.org/articles/PMC8195330

Europe_PMChttps://europepmc.org/articles/PMC8195330?pdf=render

https://doi.org/10.3389/fimmu.2021.683803

https://www.frontiersin.org/articles/10.3389/fimmu.2021.683803/pdf

https://pubmed.ncbi.nlm.nih.gov/34122445

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

NeutrophilsAnimalsMice, Inbred C57BLMice, KnockoutHumansMiceVenous ThrombosisDisease Models, AnimalCaspase 1MaleInflammasomesExtracellular TrapsNLR Family, Pyrin Domain-Containing 3 ProteinProtein-Arginine Deiminase Type 4

Keywords

NeutrophilsDeep vein thrombosisNlrp3 InflammasomeNetsPad4Mcc950Male570InflammasomesImmunologyExtracellular TrapsMiceProtein-Arginine Deiminase Type 4NLR Family, Pyrin Domain-Containing 3 ProteinAnimalsHumansMice, KnockoutVenous ThrombosisCaspase 1RC581-607Mice, Inbred C57BLDisease Models, AnimalImmunologic diseases. Allergy

Sustainable Development Goals

SDG 3: 3. Good healthSDG 10: 10. No inequality