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ABCB1 and ABCG2 Overexpression Mediates Resistance to the Phosphatidylinositol 3-Kinase Inhibitor HS-173 in Cancer Cell Lines

Cells(2023)10.3390/cells12071056Source: DataRank Database

ABCB1 and ABCG2 Overexpression Mediates Resistance to the Phosphatidylinositol 3-Kinase Inhibitor HS-173 in Cancer Cell Lines is a research paper published in Cells (2023). On theSindex it has a DataRank of 0. It has been cited 11 times.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access11 citations

Cite:

Linked data & code

pdb

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (14 grants)Impact (FWCI 1.39)OA: goldTopics (57)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Cheng‐Yu Hung ORCID,Ya‐Ju Hsieh ORCID,Megumi Murakami ORCID,Yang-Hui Huang,Tsung-Yao Su

Live enrichment

PubMed:37048130 PMC:PMC10093605 OpenAlex:https://openalex.org/W4362450544

Ministry of Science and Technology, Taiwan

Grant: MOST-111-2320-B-182-018

Ministry of Science and Technology, Taiwan

Grant: MOST-110-2113-M-029-006

Ministry of Science and Technology, Taiwan

Grant: MOST 109-2320-B-182-009-MY3

Ministry of Science and Technology, Taiwan

Grant: MOST 111-2622-B-182-001

Ministry of Science and Technology, Taiwan

Grant: 109-2314-B-182A-097-MY3

Ministry of Science and Technology, Taiwan

Grant: CMRPD1M0581

Ministry of Science and Technology, Taiwan

Grant: BMRPC17

Ministry of Science and Technology, Taiwan

Grant: CLRPD1J0014

Ministry of Science and Technology, Taiwan

Grant: TCVGH-T1107807

Ministry of Science and Technology, Taiwan

Grant: 010030

Intramural NIH HHS

Grant: ZIA BC010030

National Institutes of Health

Grant: n/a

Ministry of Science and Technology

Grant: MOST-111-2320-B-182-018, MOST 109-2320-B-182-009-MY3, MOST 111-2622-B-182-001, 109-2314-B-182A-097-MY3

Chang Gung Memorial Hospital

Grant: CMRPD1M0581 and BMRPC17 and CLRPD1J0014

FWCI

1.39

Citation Percentile

0.8%

Citation Trend

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://www.mdpi.com/2073-4409/12/7/1056/pdf?version=1680742606

publisherhttps://www.mdpi.com/2073-4409/12/7/1056/pdf?version=1680742606

publisherhttps://www.mdpi.com/2073-4409/12/7/1056/pdf

journalhttps://doi.org/10.3390/cells12071056

repositoryhttps://pubmed.ncbi.nlm.nih.gov/37048130

Fields of Study

Drug Transport and Resistance MechanismsHIV/AIDS drug development and treatmentCancer therapeutics and mechanismsHumansDrug Resistance, MultiplePhosphatidylinositol 3-KinasesApoptosisDrug Resistance, NeoplasmCell Line, TumorG2 Phase Cell Cycle CheckpointsATP-Binding Cassette TransportersPhosphoinositide-3 Kinase InhibitorsNeoplasmsATP Binding Cassette Transporter, Subfamily G, Member 2Neoplasm ProteinsATP Binding Cassette Transporter, Subfamily BPyridinesSulfonamides

MeSH Terms

ATP Binding Cassette Transporter, Subfamily G, Member 2Phosphoinositide-3 Kinase InhibitorsHumansNeoplasm ProteinsNeoplasmsPyridinesSulfonamidesApoptosisDrug Resistance, MultipleATP Binding Cassette Transporter, Subfamily BATP-Binding Cassette TransportersDrug Resistance, NeoplasmPhosphatidylinositol 3-KinasesCell Line, TumorG2 Phase Cell Cycle Checkpoints

Keywords

Abcg2EffluxMultiple drug resistancePI3K/AKT/mTOR pathwayATP-binding cassette transporterCancer cellIntracellularProtein kinase BTransporterPharmacologyKinaseApoptosisDrug resistanceBiologyCancer researchCancerChemistryCell biologyBiochemistryGeneticsMultidrug resistancePI3KAbcb1Hs-173

Sustainable Development Goals

SDG 0: Good health and well-being