Megumi Murakami

Also affiliated with Cancer Institute (WIA), National Cancer Institute, Center for Cancer Research

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

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Indexed papers

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 19 papers. Top paper: “Branebrutinib (BMS-986195), a Bruton’s Tyrosine Kinase Inhibitor, Resensitizes P-Glycoprotein-Overexpressing Multidrug-Resistant Cancer Cells to Chemotherapeutic Agents”.

Branebrutinib (BMS-986195), a Bruton’s Tyrosine Kinase Inhibitor, Resensitizes P-Glycoprotein-Overexpressing Multidrug-Resistant Cancer Cells to Chemotherapeutic Agents

Frontiers in Cell and Developmental Biology(2021)10.3389/fcell.2021.699571

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11 citations

Megumi Murakami, Yu‐Shan Wu, Ya-Chen Chi, Sung-Han Hsiao, Yang-Hui Huang +3 more

The multi-targeted tyrosine kinase inhibitor SKLB610 resensitizes ABCG2-overexpressing multidrug-resistant cancer cells to chemotherapeutic drugs

Biomedicine & Pharmacotherapy(2022)10.1016/j.biopha.2022.112922

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10 citations

Megumi Murakami, Yu‐Shan Wu, Chun‐Ling Lin, Yanqing Li, Yang-Hui Huang +3 more

ABCB1 limits the cytotoxic activity of TAK-243, an inhibitor of the ubiquitin-activating enzyme UBA1

Frontiers in Bioscience-Landmark(2022)10.31083/j.fbl2701005

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9 citations

Yuqi Yang, Zi‐Ning Lei, Silpa Narayanan, Jing‐Quan Wang, Qiu‐Xu Teng +5 more

Interaction of A3 adenosine receptor ligands with the human multidrug transporter ABCG2

European Journal of Medicinal Chemistry(2022)10.1016/j.ejmech.2022.114103

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8 citations

Megumi Murakami, Dilip K. Tosh, Jinha Yu, Sabrina Lusvarghi, Ryan G. Campbell +4 more

Hydroxygenkwanin Improves the Efficacy of Cytotoxic Drugs in ABCG2-Overexpressing Multidrug-Resistant Cancer Cells

International Journal of Molecular Sciences(2022)10.3390/ijms232112763

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2 citations

Megumi Murakami, Yang-Hui Huang, Tai‐Ho Hung, Shun-Ping Wang, Yu‐Shan Wu +3 more

Furmonertinib, a Third-Generation EGFR Tyrosine Kinase Inhibitor, Overcomes Multidrug Resistance through Inhibiting ABCB1 and ABCG2 in Cancer Cells

International Journal of Molecular Sciences(2023)10.3390/ijms241813972

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17 citations

Yen-Ching Li, Megumi Murakami, Sung-Han Hsiao, Yun-Chieh Lee, Yang-Hui Huang +5 more

ABCB1 and ABCG2 Overexpression Mediates Resistance to the Phosphatidylinositol 3-Kinase Inhibitor HS-173 in Cancer Cell Lines

Cells(2023)10.3390/cells12071056

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11 citations

Cheng‐Yu Hung, Ya‐Ju Hsieh, Megumi Murakami, Yang-Hui Huang, Tsung-Yao Su +5 more

Design, Synthesis and Biological Evaluation of Quinazolinamine Derivatives as Breast Cancer Resistance Protein and P-Glycoprotein Inhibitors with Improved Metabolic Stability

Biomolecules(2023)10.3390/biom13020253

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9 citations

Qiu‐Xu Teng, Megumi Murakami, Suresh V. Ambudkar, Zhe‐Sheng Chen, Vijaya L. Korlipara +1 more

Epidermal Growth Factor Receptor Inhibitor Mobocertinib Resensitizes Multidrug-Resistant Cancer Cells by Attenuating the Human ATP-Binding Cassette Subfamily B Member 1 and Subfamily G Member 2

ACS Pharmacology & Translational Science(2023)10.1021/acsptsci.3c00217

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7 citations

Sung-Han Hsiao, Megumi Murakami, Yang-Hui Huang, Yu‐Tzu Chang, Tai‐Ho Hung +4 more

Second-site suppressor mutations reveal connection between the drug-binding pocket and nucleotide-binding domain 1 of human P-glycoprotein (ABCB1)

Drug Resistance Updates(2023)10.1016/j.drup.2023.101009

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8 citations

Andaleeb Sajid, Sabrina Lusvarghi, Stewart R. Durell, Biebele Abel, Shahrooz Vahedi +3 more

Imperatorin Restores Chemosensitivity of Multidrug-Resistant Cancer Cells by Antagonizing ABCG2-Mediated Drug Transport

Pharmaceuticals(2023)10.3390/ph16111595

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3 citations

Megumi Murakami, Yen-Ching Li, Yang-Hui Huang, Yu‐Tzu Chang, Tai‐Ho Hung +3 more

Epertinib counteracts multidrug resistance in cancer cells by antagonizing the drug efflux function of ABCB1 and ABCG2

Biomedicine & Pharmacotherapy(2024)10.1016/j.biopha.2024.117542

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6 citations

Yen-Ching Li, Megumi Murakami, Yu‐Shan Wu, Yang-Hui Huang, Tai‐Ho Hung +3 more

Vodobatinib overcomes cancer multidrug resistance by attenuating the drug efflux function of ABCB1 and ABCG2

European Journal of Pharmacology(2024)10.1016/j.ejphar.2024.177231

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3 citations

Bing-Huan Lin, Megumi Murakami, Yu‐Shan Wu, Tai‐Ho Hung, Suresh V. Ambudkar +2 more

Mutational analysis reveals the importance of residues of the access tunnel inhibitor site to human P‐glycoprotein (ABCB1)‐mediated transport

Protein Science(2024)10.1002/pro.5155

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6 citations

Megumi Murakami, Nandhini Ranganathan, Stewart R. Durell, Suresh V. Ambudkar, Paula Salazar

The colony-stimulating factor-1 receptor inhibitor edicotinib counteracts multidrug resistance in cancer cells by inhibiting ABCG2-mediated drug efflux

Biomedicine & Pharmacotherapy(2024)10.1016/j.biopha.2024.117554

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2 citations

Yun-Chieh Lee, Megumi Murakami, Yang-Hui Huang, Tai‐Ho Hung, Yu‐Shan Wu +3 more

ABCG2 Mediates Resistance to the Dual EGFR and PI3K Inhibitor MTX-211 in Cancer Cells

International Journal of Molecular Sciences(2024)10.3390/ijms25105160

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1 citations

Cheng‐Yu Hung, Megumi Murakami, Yu‐Shan Wu, Yi-Hsuan Chu, Yang-Hui Huang +3 more

Structure-activity relationship studies on 2-thienylidene substituted 3-oxo-2,3-dihydrobenzofuran-7-carboxamides as poly (ADP-ribose) polymerase inhibitors

Bioorganic Chemistry(2025)10.1016/j.bioorg.2025.108941

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1 citations

Ugochi A. Adiele, Griffin Coate, Morgan E. Diolaiti, Huadong Chen, Junhao Lu +11 more

Conversion of Human Multidrug Transporter P-glycoprotein (ABCB1) from Drug Efflux to Uptake Pump: Evidence for a Switch Region Modulating the Direction of Substrate Transport

Journal of Molecular Biology(2025)10.1016/j.jmb.2025.168979

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1 citations

Nandhini Ranganathan, Rajan Guha, Megumi Murakami, Shafaq Ahmed, Stewart R. Durell +2 more

The fourth-generation EGFR tyrosine kinase inhibitor BLU-945 resensitizes ABCG2-overexpressing multidrug-resistant non-small cell lung cancer cells to cytotoxic anticancer drugs

European Journal of Pharmaceutical Sciences(2025)10.1016/j.ejps.2025.107337

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0 citations

Bing-Huan Lin, Megumi Murakami, Yu‐Shan Wu, Tai‐Ho Hung, Suresh V. Ambudkar +2 more