Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Mutational Scanning and Binding Free Energy Computations of the SARS-CoV-2 Spike Complexes with Distinct Groups of Neutralizing Antibodies: Energetic Drivers of Convergent Evolution of Binding Affinity and Immune Escape Hotspots

International Journal of Molecular Sciences(2025)10.3390/ijms26041507Source: DataRank Database

Mutational Scanning and Binding Free Energy Computations of the SARS-CoV-2 Spike Complexes with Distinct Groups of Neutralizing Antibodies: Energetic Drivers of Convergent Evolution of Binding Affinity and Immune Escape Hotspots is a research paper published in International Journal of Molecular Sciences (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

N/A

0DataRank · unranked

Scored on demand from live citation data

Open Access1 citations

Download PDF

Cite:

Linked data & code

pdb

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 0.82)OA: goldTopics (48)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

Run a calibrated FAIR evaluation for this paper →

We only score data papers we can read in full — never from an abstract alone.

Authors (5)

Vedant Parikh ORCID,Brandon Foley,Nishank Raisinghani ORCID,Gennady M. Verkhivker ORCID,Mohammed Alshahrani ORCID

Live enrichment

PubMed:40003970 PMC:PMC11855367 OpenAlex:https://openalex.org/W4407373751

National Institutes of Health

Grant: 1R01AI181600-01

National Institutes of Health

Grant: 6069-SC24-11

NIH HHS

Grant: 1R01AI181600-01 Subaward 6069-SC24-11

NIAID NIH HHS

Grant: R01 AI181600

FWCI

0.82

Citation Percentile

0.7%

Citation Trend

2025

goldLicense: cc-by

journalhttps://www.mdpi.com/1422-0067/26/4/1507/pdf?version=1739269528

publisherhttps://www.mdpi.com/1422-0067/26/4/1507/pdf?version=1739269528

publisherhttps://www.mdpi.com/1422-0067/26/4/1507/pdf

journalhttps://doi.org/10.3390/ijms26041507

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40003970

Fields of Study

SARS-CoV-2 and COVID-19 ResearchMonoclonal and Polyclonal Antibodies Researchvaccines and immunoinformatics approachesSpike Glycoprotein, CoronavirusAntibodies, NeutralizingSARS-CoV-2Antibodies, ViralHumansImmune EvasionThermodynamicsMutationCOVID-19Protein BindingMolecular Dynamics SimulationEvolution, MolecularBinding Sites

MeSH Terms

COVID-19SARS-CoV-2Antibodies, ViralBinding SitesHumansMutationProtein BindingThermodynamicsEvolution, MolecularMolecular Dynamics SimulationImmune EvasionAntibodies, NeutralizingSpike Glycoprotein, Coronavirus

Keywords

AntibodyImmune escapeEpitopeNeutralizationBiologyComputational biologyBinding siteImmune systemVirologyNeutralizing antibodyGeneticsMolecular dynamicsProtein StabilityAntibody BindingBinding EnergeticsEvolutionary MechanismsMutational ScanningSars-cov-2 Spike ProteinOmicron Variants

Sustainable Development Goals

SDG 0: Affordable and clean energy