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Synthesis and Evaluation of Novel 1,2,6-Thiadiazinone Kinase Inhibitors as Potent Inhibitors of Solid Tumors

Molecules(2021)10.3390/molecules26195911Source: DataRank Database

Synthesis and Evaluation of Novel 1,2,6-Thiadiazinone Kinase Inhibitors as Potent Inhibitors of Solid Tumors is a research paper published in Molecules (2021). On theSindex it has a DataRank of 0. It has been cited 5 times.

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Open Access5 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)Impact (FWCI 0.39)OA: goldTopics (49)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Michael P. East ORCID,Tuomo Laitinen ORCID,Chad Torrice,Kaitlyn Maffuid ORCID,David H. Drewry ORCID

Live enrichment

PubMed:34641454 PMC:PMC8513058 OpenAlex:https://openalex.org/W3202531487

Cyprus Research Promotion Foundation

Grant: NEAYPODOMH/NEKYP/0308/02

NIDDK NIH HHS

Grant: U24 DK116204

National Institutes of Health

Grant: 5U24DK116204-04

Illuminating Function of the Understudied Druggable Kinome

Wellcome Trust

Grant: unidentified

unidentified

National Science Foundation

Grant: 1726291

MRI: Acquisition of a Mass Spectrometer

Wellcome Trust

FWCI

0.39

Citation Percentile

0.5%

Citation Trend

2022

2025

goldLicense: cc-by

journalhttps://www.mdpi.com/1420-3049/26/19/5911/pdf?version=1634024476

publisherhttps://www.mdpi.com/1420-3049/26/19/5911/pdf?version=1634024476

publisherhttps://www.mdpi.com/1420-3049/26/19/5911/pdf

journalhttps://doi.org/10.3390/molecules26195911

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34641454

Fields of Study

Quinazolinone synthesis and applicationsSynthesis and biological activityClick Chemistry and Applications0301 basic medicine03 medical and health sciences

MeSH Terms

Antineoplastic AgentsDose-Response Relationship, DrugDrug Screening Assays, AntitumorHumansNeoplasmsStructure-Activity RelationshipThiadiazinesTumor Cells, CulturedDrug DesignMolecular StructureProtein Kinase InhibitorsCell Proliferation

Keywords

Prostate cancerCancer researchKinaseCell cultureFibroblastChemistryMedicineCancerInternal medicineBiologyBiochemistryLung cancerBreast cancerBladder cancerChordomaPancreatic cancerThiadiazinoneDose-Response Relationship, DrugMolecular StructureThiadiazinesOrganic chemistryAntineoplastic AgentsArticleStructure-Activity RelationshipQD241-441Drug DesignNeoplasmsTumor Cells, CulturedHumansDrug Screening Assays, AntitumorProtein Kinase InhibitorsCell Proliferation

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Synthesis and Evaluation of Novel 1,2,6-Thiadiazinone Kinase Inhibitors as Potent Inhibitors of Solid Tumors

FAIR Checklist

Authors (10)

Funding (6 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)