Michael P. East

University of North Carolina at Chapel Hill

ORCID: 0000-0002-1994-6117

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 26 papers. Top paper: “PRM-LIVE with Trapped Ion Mobility Spectrometry and Its Application in Selectivity Profiling of Kinase Inhibitors”.

PRM-LIVE with Trapped Ion Mobility Spectrometry and Its Application in Selectivity Profiling of Kinase Inhibitors

Analytical Chemistry(2021)10.1021/acs.analchem.1c02349

N/A

0.520DataRank · unranked

31 citations

Scott B. Ficarro, William M. Alexander, Laura E. Fleming, Guillaume Adelmant, Tinghu Zhang +10 more

FOXA1 and adaptive response determinants to HER2 targeted therapy in TBCRC 036

npj Breast Cancer(2021)10.1038/s41523-021-00258-0

N/A

0.483DataRank · unranked

24 citations

Timothy J. Stuhlmiller, Gaurav Mehta, Samantha M. Bevill, Daniel R. Goulet, José F. Olivares-Quintero +25 more

Quantitative proteomic mass spectrometry of protein kinases to determine dynamic heterogeneity of the human kinome

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.04.614143

N/A

0.181DataRank · unranked

2 citations

Robert W. Sprung, Denis O. Okumu, José F. Olivares-Quintero, Chinmaya U. Joisa, Xin Chen +21 more

Kinase Plasticity with Vandetanib Treatment Enhances Sensitivity to Tamoxifen in Estrogen Receptor Positive Breast Cancer

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.19.629395

N/A

0.174DataRank · unranked

2 citations

Rasha T. Kakati, Santiago Haase, Christine Thai, Attila Szénási, Elizabeth Brunk +10 more

Synthesis and Evaluation of Novel 1,2,6-Thiadiazinone Kinase Inhibitors as Potent Inhibitors of Solid Tumors

Molecules(2021)10.3390/molecules26195911

N/A

0DataRank · unranked

5 citations

Michael P. East, Tuomo Laitinen, Chad Torrice, Kaitlyn Maffuid, David H. Drewry +5 more

The ARF GAPs ELMOD1 and ELMOD3 act at the Golgi and Cilia to Regulate Ciliogenesis and Ciliary Protein Traffic

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.15.460558

N/A

0DataRank · unranked

4 citations

Yihan Hu, Skylar I. Dewees, Narra S. Devi, Michael P. East, Katherine R. Hardin +8 more

Small-molecule inhibition of the archetypal UbiB protein COQ8

Nature Chemical Biology(2022)10.1038/s41589-022-01168-3

N/A

0DataRank · unranked

10 citations

Christopher R. M. Asquith, Zixiang Fang, Michael P. East, Naomi Ptak, Robert Smith +8 more

Identification of 4‐Anilinoquin(az)oline as a Cell‐Active Protein Kinase Novel 3 (PKN3) Inhibitor Chemotype**

ChemMedChem(2022)10.1002/cmdc.202200161

N/A

0DataRank · unranked

3 citations

Louisa Temme, Michael P. East, Tuomo Laitinen, Julie E. Pickett, Frank E. Kwarcinski +6 more

SMALL MOLECULE CLPP AGONISTS INDUCE SENESCENCE AND ALTER TRAIL-MEDIATED APOPTOTIC RESPONSE OF TRIPLE-NEGATIVE BREAST CANCER CELLS

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.11.499620

N/A

0DataRank · unranked

3 citations

Emily M.J. Fennell, Michael P. East, Thomas S.K. Gilbert, Paul R. Graves, Hani Ashamalla +5 more

Numb-associated kinases are required for SARS-CoV-2 infection and are cellular targets for therapy

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.18.484178

N/A

0DataRank · unranked

1 citations

Sirle Saul, Luca Ghita, Malaya K. Sahoo, Chengjin Ye, Nishank Bhalla +12 more

Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity Relationships

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.28.573261

N/A

0DataRank · unranked

1 citations

Michael P. East, Tuomo Laitinen, Carla Alamillo‐Ferrer, Erkka Hartikainen, Carrow I. Wells +7 more

Combined kinome inhibition states are predictive of cancer cell line sensitivity to kinase inhibitor combination therapies

PubMed(2023)10.1142/9789811286421_0022

N/A

0DataRank · unranked

0 citations

Kevin A. Chen, Samantha Beville, Timothy J. Stuhlmiller, Matthew E. Berginski, Denis O. Okumu +5 more

Tumor-Intrinsic Kinome Landscape of Pancreatic Cancer Reveals New Therapeutic Approaches

Cancer Discovery(2024)10.1158/2159-8290.cd-23-1480

N/A

0DataRank · unranked

5 citations

Xianlu Laura Peng, Michael P. East, Ian C. McCabe, Grace C. Stroman, Madison R. Jenner +16 more

Discovery and optimization of narrow spectrum inhibitors of Tousled like kinase 2 (TLK2) using quantitative structure activity relationships

European Journal of Medicinal Chemistry(2024)10.1016/j.ejmech.2024.116357

N/A

0DataRank · unranked

3 citations

Michael P. East, Tuomo Laitinen, Carla Alamillo‐Ferrer, Erkka Hartikainen, Carrow I. Wells +7 more

PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.15.589676

N/A

0DataRank · unranked

2 citations

Manjari Mishra, Chieh‐Wen Lo, Sirle Saul, H. Busra Cagirici, Do Hoang Nhu Tran +22 more

Irreversible JNK1-JUN inhibition by JNK-IN-8 sensitizes pancreatic cancer to 5-FU/FOLFOX chemotherapy

UNC Libraries(2024)10.17615/76z2-h138

N/A

0DataRank · unranked

0 citations

Silvia G. Herrera Loeza, Yi Xu, Richard A. Moffitt, Chong Jin, Ashley B. Morrison +10 more

Application of Integrated Drug Screening/Kinome Analysis to Identify Inhibitors of Gemcitabine-Resistant Pancreatic Cancer Cell Growth

UNC Libraries(2024)10.17615/jadh-1012

N/A

0DataRank · unranked

0 citations

Laura E. Herring, Alison D. Axtman, Michael P. East, Benjamin Lee, Denis O. Okumu +12 more

Mass spectrometry-based selectivity profiling identifies a highly selective inhibitor of the kinase MELK that delays mitotic entry in cancer cells

UNC Libraries(2024)10.17615/bmvq-pm20

N/A

0DataRank · unranked

0 citations

Laura E. Herring, Michael P. East, Cyrus Vaziri, Dennis Goldfarb, Emily Wilkerson +7 more

PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2

Nature Communications(2025)10.1038/s41467-025-61759-1

N/A

0DataRank · unranked

10 citations

Manjari Mishra, Chieh‐Wen Lo, Sirle Saul, H. Busra Cagirici, Manon Gourdelier +29 more

Kinome Reprogramming of G2/M Kinases and Repression of MYCN Contribute to Superior Efficacy of Lorlatinib in ALK-Driven Neuroblastoma

Molecular Cancer Therapeutics(2025)10.1158/1535-7163.mct-24-0684

N/A

0DataRank · unranked

4 citations

Michael P. East, Timothy J. Stuhlmiller, Gabriela M. Witek, Alvin Farrel, Steven Pastor +13 more

Combined kinome inhibition states are predictive of cancer cell line sensitivity to kinase inhibitor combination therapies.

UNC Libraries(2025)10.17615/tg7c-sn11

N/A

0DataRank · unranked

0 citations

Shawn M. Gomez, Gary L. Johnson, Chinmaya U. Joisa, Kevin A. Chen, Samantha Beville +5 more

The ARF GAP ELMOD2 acts with different GTPases to regulate centrosomal microtubule nucleation and cytokinesis

Molecular Biology of the Cell(2020)10.1091/mbc.e20-01-0012

N/A

0DataRank · unranked

19 citations

Michael P. East, Rytis Prekeris, Richard Kahn, Rachel E. Turn

Kinome reprogramming of G2/M kinases and repression of MYCN contribute to superior efficacy of lorlatinib in ALK-driven neuroblastoma.

UNC Libraries(2025)10.17615/pbz0-mn14

N/A

0DataRank · unranked

0 citations

Mark Gerelus, Michael P. East, Alvin Farrel, Steven Pastor, John M. Maris +13 more

Mass spectrometry–based selectivity profiling identifies a highly selective inhibitor of the kinase MELK that delays mitotic entry in cancer cells

Journal of Biological Chemistry(2020)10.1074/jbc.ra119.011083

N/A

0DataRank · unranked

30 citations

Gavin D. Grant, Michael P. East, Thomas S.K. Gilbert, Emily Wilkerson, Dennis Goldfarb +7 more

Kinome Profiling Identifies Druggable Targets for Novel Human Cytomegalovirus (HCMV) Antivirals

UNC Libraries(2020)10.17615/4en3-d531

N/A

0DataRank · unranked

0 citations

Laura E. Herring, Heather A. Vincent, Kyle C. Arend, Ian M. McDonald, Thomas S.K. Gilbert +7 more

Adaptive chromatin remodeling and transcriptional changes of the functional kinome in tumor cells in response to targeted kinase inhibition

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101525

N/A

0DataRank · unranked

22 citations

Gary L. Johnson, Michael P. East