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Potent MOR Agonists from 2′-Hydroxy-5,9-dimethyl-N-phenethyl Substituted-6,7-benzomorphans and from C8-Hydroxy, Methylene and Methyl Derivatives of N-Phenethylnormetazocine

Molecules(2023)10.3390/molecules28237709Source: DataRank Database

Potent MOR Agonists from 2′-Hydroxy-5,9-dimethyl-N-phenethyl Substituted-6,7-benzomorphans and from C8-Hydroxy, Methylene and Methyl Derivatives of N-Phenethylnormetazocine is a research paper published in Molecules (2023). On theSindex it has a DataRank of 0. It has been cited 2 times.

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Open Access2 citations

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Linked data & code

CCDC 2290877: Experimental Crystal Structure Determination · Cambridge Crystallographic Data Centre

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 0.19)OA: goldTopics (31)Linked Datasets (1)DataCite Reuse (1)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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Authors (9)

George W. Ward,Agnieszka Sulima ORCID,Dan Luo ORCID,Thomas E. Prisinzano ORCID,Gregory H. Imler ORCID

Live enrichment

PubMed:38067439 PMC:PMC10708259 OpenAlex:https://openalex.org/W4388901995

National Institute on Drug Abuse

Grant: DA051377

National Institute on Drug Abuse

Grant: Interagency Agreement #Y1-DA1101

NIDA NIH HHS

Grant: U01 DA051377

Kentucky Medical Services Foundation

FWCI

0.19

Citation Percentile

0.5%

Citation Trend

2024

2025

goldLicense: cc-by

journalhttps://www.mdpi.com/1420-3049/28/23/7709/pdf?version=1700647015

publisherhttps://www.mdpi.com/1420-3049/28/23/7709/pdf?version=1700647015

publisherhttps://www.mdpi.com/1420-3049/28/23/7709/pdf

journalhttps://doi.org/10.3390/molecules28237709

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38067439

Fields of Study

Chemical Synthesis and AnalysisNeuropeptides and Animal PhysiologyNeuroscience and Neuropharmacology ResearchBenzomorphansMorphineEthylaminesIndolesStructure-Activity Relationship

MeSH Terms

BenzomorphansEthylaminesIndolesMorphineStructure-Activity Relationship

Keywords

MoietyChemistryStereochemistryPotencyEthylamineMethyleneIndole testSubstituentMedicinal chemistryIn vitroBiochemistryOrganic chemistryOpioidInhibition Of Forskolin-induced Camp Accumulation Assay (Camp Assay)C8-Alkenyl Substituted 6,7-BenzomorphansC8-Alkyl Substituted 6,7-BenzomorphansN-Phenethyl Analogs Of 6,7-BenzomorphansN-Phenethylnormetazocine Derivatives

Sustainable Development Goals

SDG 0: Clean water and sanitation

CCDC 2290877: Experimental Crystal Structure Determination

10.5517/ccdc.csd.cc2gwv8hCambridge Crystallographic Data Centre