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Piperidine CD4-Mimetic Compounds Expose Vulnerable Env Epitopes Sensitizing HIV-1-Infected Cells to ADCC

Viruses(2023)10.3390/v15051185Source: DataRank Database

Piperidine CD4-Mimetic Compounds Expose Vulnerable Env Epitopes Sensitizing HIV-1-Infected Cells to ADCC is a research paper published in Viruses (2023). On theSindex it has a DataRank of 0. It has been cited 12 times.

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Enrichment:Funding (25 grants)OA: goldTopics (30)IDs (PubMed, PMC)Annotations (1)

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Authors (17)

William D. Tolbert ORCID,Huile Zhu,Daniel Lee ORCID,Lorie Marchitto ORCID,Tyler F. Higgins ORCID

Live enrichment

PubMed:37243271 PMC:PMC10220648

P01-GM56550/AI150741

Grant: 352417

P01-GM56550/AI150741

Grant: 422148

P01-GM56550/AI150741

Grant: 41027

P01-GM56550/AI150741

Grant: R01 AI148379

P01-GM56550/AI150741

Grant: R01 AI150322

P01-GM56550/AI150741

Grant: R01 AI129769

P01-GM56550/AI150741

Grant: AI116274

P01-GM56550/AI150741

Grant: AI120756

P01-GM56550/AI150741

Grant: RCHS0235 950-232424

NIAID NIH HHS

Grant: UM1 AI164562

NIAID NIH HHS

Grant: P01 AI150471

NIAID NIH HHS

Grant: P01 AI162242

NIGMS NIH HHS

Grant: P01 GM056550

National Institutes of Health

Grant: 1R01AI150322-01

Characterizing HIV-1 Env conformations susceptible to attack by non-neutralizing antibodies

Canadian Institutes of Health Research

Grant: unidentified

unidentified

National Institutes of Health

Grant: 5R01AI148379-02

Assessing ADCC and Fc-mediated Protection against HIV

National Institutes of Health

Grant: 1R01AI129769-01

Unlocking Env: A New Strategy for a Functional Cure Through Antibody-Dependent Cell-Mediated Cytotoxicity

National Institutes of Health

Grant: 1UM1AI164562-01

Enterprise for Research and Advocacy to Stop and Eradicate HIV (ERASE-HIV)

National Institutes of Health

Grant: 7R01AI116274-04

Structural Targeting of Potentially Protective gp120 Epitopes in the C1/C2 Region

National Institutes of Health

Grant: 3P01GM056550-16S1

Structure-Based Antagonism of HIV-1 Envelope Function in Cell Entry

National Institute of Allergy and Infectious Diseases

National Institute of Diabetes and Digestive and Kidney Diseases

National Institute on Drug Abuse

National Heart, Lung, and Blood Institute

National Institute of Neurological Disorders and Stroke

goldLicense: cc-by

publisherhttps://www.mdpi.com/1999-4915/15/5/1185/pdf?version=1684311125

publisherhttps://www.mdpi.com/1999-4915/15/5/1185/pdf

repositoryhttps://www.osti.gov/servlets/purl/2471687

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10220648/pdf/viruses-15-01185.pdf

repositoryhttps://doaj.org/article/52e7e420c9a942b2be25abc6e48e553d

Fields of Study

0301 basic medicine03 medical and health sciences

MeSH Terms

CD4-Positive T-LymphocytesHumansHIV-1HIV InfectionsHIV SeropositivityHIV Envelope Protein gp120HIV AntibodiesEpitopesAntibody-Dependent Cell CytotoxicityCD4 Antigens

Keywords

HIV-1NeutralizationAntibody-dependent Cellular Cytotoxicity (Adcc)Envelope GlycoproteinsPhe43 CavitySmall Cd4 Mimetic Compounds (Cd4mc)CD4-Positive T-LymphocytesAntibody-Dependent Cell CytotoxicityHIV InfectionsHIV Envelope Protein gp120HIV AntibodiesMicrobiologyQR1-502ArticleEpitopesCD4 AntigensHIV SeropositivityHumans