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Small proline-rich proteins (SPRRs) are epidermally produced antimicrobial proteins that defend the cutaneous barrier by direct bacterial membrane disruption

eLife(2022)10.7554/elife.76729Source: DataRank Database

Small proline-rich proteins (SPRRs) are epidermally produced antimicrobial proteins that defend the cutaneous barrier by direct bacterial membrane disruption is a research paper published in eLife (2022). On theSindex it has a DataRank of 1.5. It has been cited 48 times, with 44 citing works in its 1-hop citation network.

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1.5DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access48 citations · 44 citing works in its network

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Linked data & code

cellosaurus

Data availability

Repositories this paper deposited data in (declared in PubMed).

GEOGSE182756

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)OA: goldTopics (38)Linked Datasets (8)DataCite Reuse (8)IDs (PubMed, PMC)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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DataRank Breakdown

Base Score 38%Citation Network 62%

Base Score Contribution

0.584

From this paper's citation signal

Citation Network Contribution

0.938

From 33 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 44 citers.

Crosstalk between skin microbiota and immune system in health and disease
Nature Immunology202341 citations16 referencesContributes 0.234
Microbiota and maintenance of skin barrier function
Science2022630 citations70 referencesContributes 0.092
Autologous transplantation of P63 + lung progenitor cells for chronic obstructive pulmonary disease therapy
Science Translational Medicine202436 citations58 referencesContributes 0.062
Molecular fingerprint by omics‐based approaches in saliva from patients affected by SARS‐CoV‐2 infection
Journal of Mass Spectrometry20247 citations38 referencesContributes 0.055
A role for arginase in skin epithelial differentiation and antimicrobial peptide production
British Journal of Dermatology20258 citations41 referencesContributes 0.054

Authors (8)

Zehan Hu ORCID,Abdul G Lone,Methinee Artami ORCID,Marshall Edwards ORCID,Christos C. Zouboulis ORCID

Live enrichment

PubMed:35234613 PMC:PMC8912919

National Institutes of Health

Grant: AR076459-01

Robert Wood Johnson Foundation

Grant: Amos

Burroughs Wellcome Fund

Grant: CAMS

NIAMS NIH HHS

Grant: K08 AR076459

National Institutes of Health

Grant: 1K08AR076459-01

The Function of Small Proline Rich Proteins in Cutaneous Host Defense

Influential Citations

goldLicense: cc-by

GOLDhttps://doi.org/10.7554/elife.76729

publisherhttps://doi.org/10.7554/elife.76729

publisherhttps://cdn.elifesciences.org/articles/76729/elife-76729-v4.pdf

publisherhttps://cdn.elifesciences.org/articles/76729/elife-76729-v4.xml

publisherhttps://elifesciences.org/articles/76729

Fields of Study

MedicineBiology0301 basic medicine03 medical and health sciences

MeSH Terms

AnimalsMiceLipopolysaccharidesProlineMembrane ProteinsAnti-Bacterial AgentsCornified Envelope Proline-Rich ProteinsMethicillin-Resistant Staphylococcus aureus

Keywords

HumanMouseLPSMicrobiologyInfectious diseaseInflammationSKinimmunologyinnate immunitySebaceous glandsAntimicrobial ProteinsLipopolysaccharidesMethicillin-Resistant Staphylococcus aureusProlineQH301-705.5ScienceQRMembrane ProteinsAnti-Bacterial AgentsMiceImmunology and InflammationCornified Envelope Proline-Rich ProteinsMedicineAnimalsBiology (General)

Sustainable Development Goals

SDG 3: 3. Good health

Additional file 3 of The mouse retinal pigment epithelium mounts an innate immune defense response following retinal detachment

10.6084/m9.figshare.26697683.v1figshare

Additional file 3 of The mouse retinal pigment epithelium mounts an innate immune defense response following retinal detachment

10.6084/m9.figshare.26697683figshare

Additional file 4 of The mouse retinal pigment epithelium mounts an innate immune defense response following retinal detachment

10.6084/m9.figshare.26697686.v1figshare

Additional file 4 of The mouse retinal pigment epithelium mounts an innate immune defense response following retinal detachment

10.6084/m9.figshare.26697686figshare

Additional file 1 of The mouse retinal pigment epithelium mounts an innate immune defense response following retinal detachment

10.6084/m9.figshare.26697677.v1figshare