Harry T. Orr

NeuroscienceBiochemistry, Genetics and Molecular BiologyImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 5%percentile

0.448Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Regional sex differences in neurochemical profiles of healthy mice measured by magnetic resonance spectroscopy at 9.4 tesla

Frontiers in Neuroscience(2023)10.3389/fnins.2023.1278828

Top 42%

0.448DataRank

Top 42%10 citations

Tiankai Xie, Nitya Shah, Sarah N. Larson, Janet M. Dubinsky, Rocío Gómez‐Pastor +5 more

Papers

Driven by 27 papers — median percentile 58. Top paper: “Patterns of CAG repeat instability in the central nervous system and periphery in Huntington’s disease and in spinocerebellar ataxia type 1”.

Patterns of CAG repeat instability in the central nervous system and periphery in Huntington’s disease and in spinocerebellar ataxia type 1

Human Molecular Genetics(2020)10.1093/hmg/ddaa139

N/A

0.742DataRank · unranked

140 citations

Larissa Arning, James V. Giordano, Pedram Razghandi, Marissa A Andrew, Tammy Gillis +19 more

Dual targeting of brain region‐specific kinases potentiates neurological rescue in Spinocerebellar ataxia type 1

The EMBO Journal(2021)10.15252/embj.2020106106

N/A

0.680DataRank · unranked

17 citations

Laura A. Lavery, Maxime W.C. Rousseaux, Eric B Rutledge, Youjin Jang, Ying‐Wooi Wan +15 more

Cross-species genetic screens identify transglutaminase 5 as a regulator of polyglutamine-expanded ataxin-1

Journal of Clinical Investigation(2022)10.1172/jci156616

N/A

0.541DataRank · unranked

12 citations

Ismael Al‐Ramahi, Hyun-Hwan Jeong, Youjin Jang, Tao Lin, Carolyn J. Adamski +11 more

Decreasing mutant ATXN1 nuclear localization improves a spectrum of SCA1-like phenotypes and brain region transcriptomic profiles

Neuron(2022)10.1016/j.neuron.2022.11.017

N/A

0.520DataRank · unranked

31 citations

Lisa Duvick, Jason S. Mitchell, Marija Cvetanović, Molly Reighard, Alyssa Soles +12 more

Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1

Neuron(2022)10.1016/j.neuron.2022.11.016

N/A

0.505DataRank · unranked

28 citations

Mark A. Durham, Larissa Nitschke, Eder Xhako, Amanda M Brown, Jean‐Pierre Revelli +11 more

The ataxin-1 interactome reveals direct connection with multiple disrupted nuclear transport pathways

Nature Communications(2020)10.1038/s41467-020-17145-0

N/A

0.483DataRank · unranked

24 citations

Nicholas A. Williamson, Lisa Duvick, Alexander Lee, Harry T. Orr, Austin Korlin-Downs +5 more

Mapping SCA1 regional vulnerabilities reveals neural and skeletal muscle contributions to disease

JCI Insight(2024)10.1172/jci.insight.176057

N/A

0.478DataRank · unranked

13 citations

William M. Southern, Kellie Benzow, Zoe N. Burch, Hillary P. Handler, Jason S. Mitchell +18 more

Regional sex differences in neurochemical profiles of healthy mice measured by magnetic resonance spectroscopy at 9.4 tesla

Frontiers in Neuroscience(2023)10.3389/fnins.2023.1278828

Top 42%

0.448DataRank

Top 42%10 citations

Tiankai Xie, Nitya Shah, Sarah N. Larson, Janet M. Dubinsky, Rocío Gómez‐Pastor +5 more

Disrupting ATXN1 Nuclear Localization in a Knock-in SCA1 Mouse Model Improves a Spectrum of SCA1-Like Phenotypes and their Brain Region Associated Transcriptomic Profiles

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.16.472987

N/A

0.208DataRank · unranked

3 citations

Lisa Duvick, Jason S. Mitchell, Marija Cvetanović, Molly Reighard, Alyssa Soles +11 more

Altered Capicua expression drives regional Purkinje neuron vulnerability through ion channel gene dysregulation in Spinocerebellar ataxia type 1

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.21.104976

N/A

0.208DataRank · unranked

3 citations

David D. Bushart, John P Cooper, Dhananjay Yellajoshyula, Logan M Morrison, Haoran Huang +5 more

Antisense Oligonucleotide Therapeutic Approach for Suppression of Ataxin-1 Expression: A Safety Assessment

Molecular Therapy — Nucleic Acids(2020)10.1016/j.omtn.2020.07.030

N/A

0DataRank · unranked

23 citations

Bente Hofstra, Hillary P. Handler, Holly Kordasiewicz, Tracy Cole, Lisa Duvick +10 more

Altered Capicua expression drives regional Purkinje neuron vulnerability through ion channel gene dysregulation in spinocerebellar ataxia type 1

Human Molecular Genetics(2020)10.1093/hmg/ddaa212

N/A

0DataRank · unranked

27 citations

David D. Bushart, John P Cooper, Dhananjay Yellajoshyula, Logan M Morrison, Haoran Huang +8 more

Reduction of mutant ATXN1 rescues premature death in a conditional SCA1 mouse model

JCI Insight(2022)10.1172/jci.insight.154442

N/A

0DataRank · unranked

8 citations

Larissa Nitschke, Meike E. van der Heijden, Nicholas A. Ciaburri, Harry T. Orr, Huda Y. Zoghbi +1 more

Cholecystokinin Activation of Cholecystokinin 1 Receptors: a Purkinje Cell Neuroprotective Pathway

The Cerebellum(2022)10.1007/s12311-022-01428-x

N/A

0DataRank · unranked

4 citations

Harry T. Orr

Longitudinal single-cell transcriptional dynamics throughout neurodegeneration in SCA1

Neuron(2023)10.1016/j.neuron.2023.10.039

N/A

0DataRank · unranked

33 citations

Neal G. Ravindra, Chang‐Woo Lee, Yubao Cheng, Billy Nguyen, Kimberly P. Luttik +22 more

The PERK pathway: beneficial or detrimental for neurodegenerative diseases and tumor growth and cancer

Human Molecular Genetics(2023)10.1093/hmg/ddad103

N/A

0DataRank · unranked

9 citations

Harry T. Orr, Zhixin Lei, Gourango Talukdar

Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1

Neuron(2023)10.1016/j.neuron.2023.02.030

N/A

0DataRank · unranked

9 citations

Mark A. Durham, Larissa Nitschke, Eder Xhako, Amanda M. Brown, Jean‐Pierre Revelli +11 more

Delineating regional vulnerability in the neurodegenerative disease SCA1 using a conditional mutant ATXN1 mouse

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.08.527710

N/A

0DataRank · unranked

2 citations

William M. Southern, Kellie Benzow, Zoe N. Burch, Hillary P. Handler, Jason S. Mitchell +17 more

Increased intrinsic membrane excitability is associated with hypertrophic olivary degeneration in spinocerebellar ataxia type 1

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.23.563657

N/A

0DataRank · unranked

0 citations

Haoran Huang, Hillary P. Handler, Min Fu, David D. Bushart, Samuel S. Pappas +3 more

Increased intrinsic membrane excitability is associated with olivary hypertrophy in spinocerebellar ataxia type 1

Human Molecular Genetics(2024)10.1093/hmg/ddae146

N/A

0DataRank · unranked

0 citations

Haoran Huang, Hillary P. Handler, Min Fu, Deborah M. Jones, David D. Bushart +4 more

An expanded polyglutamine in ATAXIN1 results in a loss-of-function that exacerbates severity of Multiple Sclerosis in an EAE mouse model

Journal of Neuroinflammation(2025)10.1186/s12974-025-03450-2

N/A

0DataRank · unranked

4 citations

Lisa Duvick, Praseuth Yang, Brennon O’Callaghan, Gavin J. Fuchs, Marija Cvetanović +2 more

Consensus Paper: Strengths and Weaknesses of Animal Models of Spinocerebellar Ataxias and Their Clinical Implications

The Cerebellum(2021)10.1007/s12311-021-01311-1

N/A

0DataRank · unranked

39 citations

Marija Cvetanović, Mandi Gandelman, Hirokazu Hirai, Harry T. Orr, Stefan M. Pulst +5 more

Repeat-associated non-AUG translation as a common mechanism for the polyGln ataxias

Cell Reports(2025)10.1016/j.celrep.2025.116741

N/A

0DataRank · unranked

3 citations

Tao Zu, Madeline Aldridge, Shu Guo, Ramadan Ajredini, Deborah K. Morrison +12 more

Modulation of ATXN1 S776 phosphorylation reveals the importance of allele-specific targeting in SCA1

JCI Insight(2021)10.1172/jci.insight.144955

N/A

0DataRank · unranked

18 citations

Stephanie L. Coffin, Eder Xhako, Dany El-Najjar, James P. Orengo, Elizabeth Alcala +6 more

Cholecystokinin 1 receptor activation restores normal mTORC1 signaling and is protective to Purkinje cells of SCA mice

Cell Reports(2021)10.1016/j.celrep.2021.109831

N/A

0DataRank · unranked

17 citations

Chen Zhao, Sharan Paul, Praseuth Yang, Karla P. Figueroa, Jill Friedrich +7 more

Longitudinal single-cell transcriptional dynamics throughout neurodegeneration in SCA1

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.22.465444

N/A

0DataRank · unranked

11 citations

Neal G. Ravindra, Billy Nguyen, Kimberly P. Luttik, Chang‐Woo Lee, John Gionco +12 more

Cholecystokinin 1 Receptor (Cck1R) Normalizes mTORC1 signaling and is Protective to Purkinje cells of SCA Mice

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.16.431490

N/A

0DataRank · unranked

0 citations

Zhao Chen, Sharan Paul, Praseuth Yang, Karla P. Figueroa, Jill Friedrich +7 more

Harry T. Orr

Indexed papers

Top data-sharing exemplar

Papers