Adam E. Locke

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

1.9Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A deep catalogue of protein-coding variation in 983,578 individuals

Nature(2024)10.1038/s41586-024-07556-0

Top 11%

1.9DataRank

Top 11%109 citations

Xiaodong Bai, Siying Chen, Suying Bao, Chuanyi Zhang, Manav Kapoor +92 more

Papers

Driven by 33 papers — median percentile 89. Top paper: “The power of genetic diversity in genome-wide association studies of lipids”.

The power of genetic diversity in genome-wide association studies of lipids

Nature(2021)10.1038/s41586-021-04064-3

N/A

9.9DataRank · unranked

1069 citations

Shoa L. Clarke, Kuan-Han H. Wu, Stavroula Kanoni, Greg J. M. Zajac, Shweta Ramdas +95 more

Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci

Nature Communications(2022)10.1038/s41467-022-29143-5

N/A

3.9DataRank · unranked

196 citations

Lap Sum Chan, Debraj Bose, Anne Jackson, Peter VandeHaar, Adam E. Locke +33 more

Exome sequencing in bipolar disorder identifies AKAP11 as a risk gene shared with schizophrenia

Nature Genetics(2022)10.1038/s41588-022-01034-x

N/A

3.5DataRank · unranked

214 citations

Daniel P. Howrigan, Sinéad B. Chapman, Rolf Adolfsson, Nick Bass, Douglas Blackwood +42 more

A deep catalogue of protein-coding variation in 983,578 individuals

Nature(2024)10.1038/s41586-024-07556-0

Top 11%

1.9DataRank

Top 11%109 citations

Xiaodong Bai, Siying Chen, Suying Bao, Chuanyi Zhang, Manav Kapoor +92 more

Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target

Nature Genetics(2023)10.1038/s41588-023-01510-y

N/A

1.6DataRank · unranked

100 citations

Derek Klarin, Michael G. Levin, Joshua M. Spin, Yae Hyun Rhee, Alicia Deng +92 more

A catalog of associations between rare coding variants and COVID-19 outcomes

medRxiv(2020)10.1101/2020.10.28.20221804

N/A

1.3DataRank · unranked

31 citations

Julie Horowitz, Nilanjana Banerjee, Rouel Lanche, Anthony Marcketta, Evan K. Maxwell +75 more

Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees

Proceedings of the National Academy of Sciences(2017)10.1073/pnas.1705859115

N/A

1.2DataRank · unranked

36 citations

Alisa Manning, Marcio Almeida, Matthew Zawistowski, Katharina Domschke, Tanya M. Teslovich +82 more

Defining the role of common variation in the genomic and biological architecture of adult human height

Nature Genetics(2014)10.1038/ng.3097

N/A

1.1DataRank · unranked

2093 citations

Emilio Rodríguez-Ruiz, The PAGE Consortium, Diana O. Perkins, Tonu Esko, Jian Yang +479 more

The genetic architecture of type 2 diabetes

Nature(2016)10.1038/nature18642

N/A

1.1DataRank · unranked

1106 citations

Menachem Fromer, Tanya M. Teslovich, Anubha Mahajan, Vineeta Agarwala, Kyle J. Gaulton +334 more

Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity

Science(2021)10.1126/science.abf8683

N/A

0.845DataRank · unranked

278 citations

Ankit Gilani, Olukayode Sosina, Jack A. Kosmicki, Lori Khrimian, Yi‐Ya Fang +55 more

A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation

Nature Genetics(2022)10.1038/s41588-022-01078-z

N/A

0.793DataRank · unranked

197 citations

Shweta Ramdas, Kimberly Lorenz, Xiuqing Guo, Rebecca Darlay, Heather J. Cordell +86 more

Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease

Nature Genetics(2022)10.1038/s41588-021-01006-7

N/A

0.780DataRank · unranked

180 citations

Jack A. Kosmicki, Amy Damask, Deepika Sharma, Genevieve H. L. Roberts, Anne E. Justice +89 more

Assessment of genetic susceptibility to multiple primary cancers through whole-exome sequencing in two large multi-ancestry studies

BMC Medicine(2022)10.1186/s12916-022-02535-6

N/A

0.731DataRank · unranked

18 citations

Linda Kachuri, Rebecca E. Graff, Jovia L. Nierenberg, Khanh K. Thai, Stacey Alexeeff +90 more

Germline Mutations in CIDEB and Protection against Liver Disease

New England Journal of Medicine(2022)10.1056/nejmoa2117872

N/A

0.728DataRank · unranked

127 citations

Mary E. Haas, Jonas B. Nielsen, Olukayode Sosina, Minhee Kim, Parsa Akbari +42 more

Quantifying the Impact of Rare and Ultra-rare Coding Variation across the Phenotypic Spectrum

The American Journal of Human Genetics(2018)10.1016/j.ajhg.2018.05.002

N/A

0.713DataRank · unranked

115 citations

F. Kyle Satterstrom, Seyedeh M. Zekavat, Indraniel Das, Mitja I Kurki, Claire Churchhouse +45 more

Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder

Molecular Psychiatry(2021)10.1038/s41380-020-01006-9

N/A

0.686DataRank · unranked

22 citations

Fernando S. Goes, Adam E. Locke, Duncan S. Palmer, Weiqing Wang, Sarah Cohen‐Woods +71 more

A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

The American Journal of Human Genetics(2022)10.1016/j.ajhg.2022.06.012

N/A

0.626DataRank · unranked

64 citations

Jonathan Judd, Sarah E. Graham, Stavroula Kanoni, Yuxuan Wang, Ida Surakka +95 more

Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

Genome biology(2022)10.1186/s13059-022-02837-1

N/A

0.626DataRank · unranked

64 citations

Sarah E. Graham, Yuxuan Wang, Ida Surakka, Shweta Ramdas, Xiang Zhu +95 more

Genomic and phenotypic correlates of mosaic loss of chromosome Y in blood

The American Journal of Human Genetics(2025)10.1016/j.ajhg.2024.12.014

N/A

0.605DataRank · unranked

14 citations

Xiaolong Ma, Adrienne M. Stilp, Fulong Yu, Jason Bacon, Justin Wong +64 more

Genome-wide analysis in 756,646 individuals provides first genetic evidence that ACE2 expression influences COVID-19 risk and yields genetic risk scores predictive of severe disease

medRxiv(2020)10.1101/2020.12.14.20248176

N/A

0.561DataRank · unranked

41 citations

Jack A. Kosmicki, Amy Damask, Deepika Sharma, Genevieve H. L. Roberts, Anne E. Justice +54 more

Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences

PLoS Genetics(2020)10.1371/journal.pgen.1009019

N/A

0.470DataRank · unranked

22 citations

Apoorva K. Iyengar, Swarooparani Vadlamudi, Chelsea K. Raulerson, Anne Jackson, Sarah M. Brotman +20 more

A trans-ancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation

medRxiv(2021)10.1101/2020.12.26.20248491

N/A

0.425DataRank · unranked

16 citations

Shweta Ramdas, Kimberly Lorenz, Xiuqing Guo, Rebecca Darlay, Heather J. Cordell +85 more

Author Correction: The power of genetic diversity in genome-wide association studies of lipids

Nature(2023)10.1038/s41586-023-06194-2

N/A

0.416DataRank · unranked

15 citations

Shoa L. Clarke, Kuan-Han H. Wu, Stavroula Kanoni, Greg J. M. Zajac, Shweta Ramdas +95 more

Exome sequencing in bipolar disorder reveals shared risk gene AKAP11 with schizophrenia

medRxiv(2021)10.1101/2021.03.09.21252930

N/A

0.366DataRank · unranked

7 citations

Daniel P. Howrigan, Sinéad B. Chapman, Rolf Adolfsson, Nick Bass, Douglas Blackwood +41 more

The power of genetic diversity in genome-wide association studies of lipids

UNC Libraries(2024)10.17615/539b-tz69

N/A

0.269DataRank · unranked

5 citations

Joel N. Hirschhorn, Zoltán Kutalik, Sanni Ruotsalainen, Daniela Ruggiero, Prashantha Hebbar +95 more

Genome-wide association study of 1,391 plasma metabolites in 6,136 Finnish men identifies 303 novel signals and provides biological insights into human diseases

medRxiv(2021)10.1101/2021.10.19.21265094

N/A

0.208DataRank · unranked

3 citations

Lap Sum Chan, Debraj Bose, Anne Jackson, Peter VandeHaar, Adam E. Locke +32 more

Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms

UNC Libraries(2020)10.17615/0ngn-wz27

N/A

0.114DataRank · unranked

1 citations

Juliana C.N. Chan, Karen L. Mohlke, Graeme I. Bell, Robin Young, Steven Wiltshire +53 more

Germline Variants Influence Chronic Liver Disease Progression through Distinct Pathways

medRxiv(2025)10.1101/2025.09.16.25335186

N/A

0.104DataRank · unranked

1 citations

David E. Kaplan, Jonas Ghouse, Bao‐Li Loza, Joseph Brancale, Adam Lewis +68 more

Genomic and phenotypic correlates of mosaic loss of chromosome Y in blood

UNC Libraries(2025)10.17615/5tss-f273

N/A

0DataRank · unranked

0 citations

Eric Boerwinkle, Yash Pershad, K.E. North, Fulong Yu, Center, Regeneron Genetics +66 more

Quality control and conduct of genome-wide association meta-analyses

UNC Libraries(2020)10.17615/e53z-k780

N/A

0DataRank · unranked

0 citations

Damien C. Croteau‐Chonka, Reedik Mägi, Joshua C. Randall, Zoltán Kutalik, Mariaelisa Graff +15 more

Across-cohort QC analyses of GWAS summary statistics from complex traits

UNC Libraries(2020)10.17615/mfev-3g68

N/A

0DataRank · unranked

0 citations

Jian Yang, Matthew R. Robinson, Sang Lee, Peter M. Visscher, Guo‐Bo Chen +12 more

Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol

UNC Libraries(2021)10.17615/shbq-nv48

N/A

0DataRank · unranked

0 citations

Douglas M. Ruderfer, Goo Jun, Ji Zhang, Yun Li, Leslie A. Lange +27 more

Integrating transcriptomics, metabolomics, and GWAS helps reveal molecular mechanisms for metabolite levels and disease risk

The American Journal of Human Genetics(2022)10.1016/j.ajhg.2022.08.007

N/A

0DataRank · unranked

62 citations

Debraj Bose, Annie Kwon, Sarah C. Hanks, Anne Jackson, Heather M. Stringham +24 more

Adam E. Locke

Indexed papers

Top data-sharing exemplar

Papers