Robert H. Heflich

National Center for Toxicological Research

Also affiliated with United States Food and Drug Administration

Biochemistry, Genetics and Molecular BiologyEnvironmental Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 13 papers. Top paper: “Revisiting the mutagenicity and genotoxicity of N-nitroso propranolol in bacterial and human in vitro assays”.

Revisiting the mutagenicity and genotoxicity of N-nitroso propranolol in bacterial and human in vitro assays

Regulatory Toxicology and Pharmacology(2023)10.1016/j.yrtph.2023.105410

N/A

0.538DataRank · unranked

35 citations

Yuan Le, Ji‐Eun Seo, Xiaoqing Guo, Yuxi Li, Si Chen +13 more

Recommendations for conducting the rodent erythrocyte Pig‐a assay: A report from the HESI GTTCPig‐a Workgroup

Environmental and Molecular Mutagenesis(2021)10.1002/em.22427

N/A

0DataRank · unranked

12 citations

Javed A. Bhalli, Daniel J. Roberts, Leon F. Stankowski, B. Bhaskar Gollapudi, David P. Lovell +5 more

Genotoxicity evaluation of nitrosamine impurities using human TK6 cells transduced with cytochrome P450s

Archives of Toxicology(2022)10.1007/s00204-022-03347-6

N/A

0DataRank · unranked

29 citations

Xiaobo He, Yuan Le, Xiaoqing Guo, Matthew Bryant, Aisar Atrakchi +6 more

Genotoxicity assessment of eight nitrosamines using 2D and 3D HepaRG cell models

Archives of Toxicology(2023)10.1007/s00204-023-03560-x

N/A

0DataRank · unranked

25 citations

Joshua Z. Yu, Hannah Xu, Xilin Li, Aisar Atrakchi, Timothy J. McGovern +5 more

Assessing the quality and making appropriate use of historical negative control data: A report of the International Workshop on Genotoxicity Testing ( IWGT )

Environmental and Molecular Mutagenesis(2023)10.1002/em.22541

N/A

0DataRank · unranked

19 citations

Dingzhou Li, Carol Beevers, George R. Douglas, Robert H. Heflich, David P. Lovell +8 more

Optimizing the detection of N-nitrosamine mutagenicity in the Ames test

Regulatory Toxicology and Pharmacology(2024)10.1016/j.yrtph.2024.105709

N/A

0DataRank · unranked

31 citations

Michelle E. Bishop, Roberta A. Mittelstaedt, Jian Yan, Sharon K Guerrero, Audrey M Sims +14 more

Mutagenicity and genotoxicity evaluation of 15 nitrosamine drug substance-related impurities in human TK6 cells

Regulatory Toxicology and Pharmacology(2024)10.1016/j.yrtph.2024.105730

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0DataRank · unranked

17 citations

Yuan Le, Xiaoqing Guo, Sruthi Tallapragada King, Robert T. Dorsam, Aisar Atrakchi +6 more

Genotoxicity evaluation of ten nitrosamine drug substance-related impurities using 2D and 3D HepaRG cell models

Regulatory Toxicology and Pharmacology(2025)10.1016/j.yrtph.2025.105906

N/A

0DataRank · unranked

10 citations

Hannah Xu, Xilin Li, Aisar Atrakchi, Timothy J. McGovern, Karen L Davis Bruno +5 more

Comparative DNA damage induced by eight nitrosamines in primary human and macaque hepatocytes

Chemico-Biological Interactions(2025)10.1016/j.cbi.2025.111538

N/A

0DataRank · unranked

5 citations

Xiaobo He, Matthew Bryant, Aisar Atrakchi, Timothy J. McGovern, Karen L Davis Bruno +3 more

Characterizing the Pulmonary Toxicity and Potential Mutagenicity of Formaldehyde Fumes in a Human Bronchial Epithelial Tissue Model

Environmental and Molecular Mutagenesis(2025)10.1002/em.70000

N/A

0DataRank · unranked

3 citations

Baiping Ren, Levan Muskhelishvili, Kelly J. Davis, Yiying Wang, William M. Gwinn +4 more

Mutation accumulation following extended exposure of human HepaRG cells to a genotoxic carcinogen

Journal of Environmental Science and Health Part C(2025)10.1080/26896583.2025.2548146

N/A

0DataRank · unranked

1 citations

Ji-Eun Seo, Jaime A. Miranda, Hannah Shibo Xu, Javier R. Revollo, Robert H. Heflich +1 more

Invited review: human air-liquid-interface organotypic airway tissue models derived from primary tracheobronchial epithelial cells—overview and perspectives

In Vitro Cellular & Developmental Biology - Animal(2020)10.1007/s11626-020-00517-7

N/A

0DataRank · unranked

147 citations

Jayme P. Coyle, Rui Xiong, Yiying Wang, Robert H. Heflich, Baiping Ren +4 more

Integration of the rat liver micronucleus assay into a 28-day treatment protocol: testing the genotoxicity of 4 small-molecule nitrosamines with different carcinogenic potencies and tumor target specificities

Toxicological Sciences(2025)10.1093/toxsci/kfaf002

N/A

0DataRank · unranked

1 citations

Ji‐Eun Seo, Hannah Xu, Jian Yan, Pritpal Malhi, Aisar Atrakchi +5 more