Gina M. DeNicola

Merck & Co., Inc., Rahway, NJ, USA (United States)

Also affiliated with Moffitt Cancer Center, Cancer Research Center, AdventHealth Tampa, University of Tampa

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 41 papers. Top paper: “Ferroptosis in health and disease”.

Ferroptosis in health and disease

Redox Biology(2024)10.1016/j.redox.2024.103211

N/A

4.5DataRank · unranked

305 citations

Hamed Alborzinia, Vera Skafar Amen, Scott Ayton, Uladzimir Barayeu, Alexander Bartelt +89 more

Targeting NRF2 and Its Downstream Processes: Opportunities and Challenges

Annual Review of Pharmacology and Toxicology(2022)10.1146/annurev-pharmtox-052220-104025

N/A

0.761DataRank · unranked

159 citations

Gina M. DeNicola, Laura Torrente

Fascin promotes lung cancer growth and metastasis by enhancing glycolysis and PFKFB3 expression

Cancer Letters(2021)10.1016/j.canlet.2021.07.025

N/A

0.701DataRank · unranked

106 citations

Yunzhan Li, Dezhen Wang, Chongbiao Huang, David Marino, Oana Bollt +8 more

Glutathione synthesis in the mouse liver supports lipid abundance through NRF2 repression

Nature Communications(2024)10.1038/s41467-024-50454-2

N/A

0.601DataRank · unranked

54 citations

Emily Tuttle, Nathan P. Ward, Yun Pyo Kang, Yumi Kim, Madeline E. Kavanagh +33 more

Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression

Cancer Research(2023)10.1158/0008-5472.can-22-3848

N/A

0.574DataRank · unranked

45 citations

Aimee Falzone, Samantha Caldwell, Nicolas Prieto-Farigua, Justin R. Prigge, Edward E. Schmidt +4 more

NADK-mediated de novo NADP(H) synthesis is a metabolic adaptation essential for breast cancer metastasis

Redox Biology(2023)10.1016/j.redox.2023.102627

N/A

0.533DataRank · unranked

34 citations

Stanislav Drápela, Tanya Schild, Nathan P. Ward, Emma Adhikari, Vivien Low +7 more

Health position paper and redox perspectives – Bench to bedside transition for pharmacological regulation of NRF2 in noncommunicable diseases

Redox Biology(2025)10.1016/j.redox.2025.103569

N/A

0.457DataRank · unranked

20 citations

Eduardo Cazalla, Anders Bach, Boushra Bathish, Sharadha Dayalan Naidu, Gina M. DeNicola +20 more

Drug screening in human physiologic medium identifies uric acid as an inhibitor of rigosertib efficacy

JCI Insight(2024)10.1172/jci.insight.174329

N/A

0.373DataRank · unranked

11 citations

Patrick DeLear, Prarthana Prashanth, Mete Emir Özgürses, Anteneh Tebeje, Philippa A. Burns +14 more

Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.24.504986

N/A

0.330DataRank · unranked

8 citations

Aimee Falzone, Samantha Caldwell, Nicolas Prieto-Farigua, Justin R. Prigge, Edward E. Schmidt +4 more

NADK upregulation is an essential metabolic adaptation that enables breast cancer metastatic colonization

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.25.485887

N/A

0.165DataRank · unranked

2 citations

Tanya Schild, Nathan P. Ward, Stanislav Drápela, Emma Adhikari, Vivien Low +5 more

Oxidation state-specific fluorescent copper sensors reveal oncogene-driven redox changes that regulate labile copper(II) pools

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2202736119

N/A

0DataRank · unranked

102 citations

Carson D. Matier, Xingxing Gu, Eric Kummelstedt, Sarah Bond, Laura Torrente +6 more

Coordinated Transcriptional and Catabolic Programs Support Iron-Dependent Adaptation to RAS–MAPK Pathway Inhibition in Pancreatic Cancer

Cancer Discovery(2022)10.1158/2159-8290.cd-22-0044

N/A

0DataRank · unranked

77 citations

Jingjie Hu, Charles Cai, Nathan P. Ward, Anthony Venida, Callum Foakes +15 more

On the illusion of auxotrophy: met15Δ yeast cells can grow on inorganic sulfur, thanks to the previously uncharacterized homocysteine synthase Yll058w

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102697

N/A

0DataRank · unranked

10 citations

Saurin Bipin Parikh, Nelson Castilho Coelho, Aaron Wacholder, Ivan A. Belashov, Sara Zdancewicz +12 more

Mitochondrial Calcium Uniporter Drives Metastasis and Confers a Targetable Cystine Dependency in Pancreatic Cancer

Cancer Research(2022)10.1158/0008-5472.can-21-3230

N/A

0DataRank · unranked

102 citations

Yunzhan Li, Zekun Li, Shengchen Lin, Hongwei Wang, Jianwei Sun +11 more

On the illusion of auxotrophy: met15Δ yeast cells can grow on inorganic sulfur thanks to the previously uncharacterized homocysteine synthase Yll058w

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.19.476918

N/A

0DataRank · unranked

5 citations

Saurin Bipin Parikh, Nelson Castilho Coelho, Aaron Wacholder, Ivan A. Belashov, Sara Zdancewicz +12 more

Can’t KEEP Up: UXS1 Dependency Exposes a Pyrimidine Vulnerability in KEAP1 -Mutant Lung Cancer

Cancer Research(2025)10.1158/0008-5472.can-25-3547

N/A

0DataRank · unranked

0 citations

Gina M. DeNicola, Basma A. Yasseen

The Origin of Cysteine and its Catabolism in Mammalian Tissues and Tumors

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.26.505162

N/A

0DataRank · unranked

0 citations

Joseph A. Combs, Aimee Falzone, Nicolas Prieto-Farigua, Samantha Caldwell, Hayley D. Ackerman +3 more

Mitochondrial Function is Preserved Under Cysteine Starvation via Glutathione Catabolism in NSCLC

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.06.511221

N/A

0DataRank · unranked

0 citations

Sang Jun Yoon, Tyce Flynn, Amanda Sherwood, Juliana Madej, Gina M. DeNicola +1 more

Genetic tools for the stable overexpression of circular RNAs

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.27.446018

N/A

0DataRank · unranked

2 citations

Arianna Nenci, Olga Vera, Aimee Falzone, Gina M. DeNicola, Florian A. Karreth +1 more

A PI3K gene expression signature predicts for recurrence in early‐stage non–small cell lung cancer treated with stereotactic body radiation therapy

Cancer(2023)10.1002/cncr.34983

N/A

0DataRank · unranked

6 citations

Amy Webb, Konstantin Shilo, Ryan Robb, Meng Xu‐Welliver, Karl Haglund +5 more

Glutathione supports lipid abundance in vivo

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.10.524960

N/A

0DataRank · unranked

3 citations

Emily Tuttle, Nathan P. Ward, Yun Pyo Kang, Yumi Kim, Madeline E. Kavanagh +33 more

Imaging the master regulator of the antioxidant response in non-small cell lung cancer with positron emission tomography

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.16.572007

N/A

0DataRank · unranked

3 citations

Richard Edwards, Will E. Tyrrell, Abigail R. Barber, Friedrich Baark, Muhammet Tanç +16 more

Data from Mitochondrial Calcium Uniporter Drives Metastasis and Confers a Targetable Cystine Dependency in Pancreatic Cancer

(2023)10.1158/0008-5472.c.6514022.v1

N/A

0DataRank · unranked

0 citations

Yunzhan Li, Zekun Li, Shengchen Lin, Hongwei Wang, Jianwei Sun +11 more

Data from Mitochondrial Calcium Uniporter Drives Metastasis and Confers a Targetable Cystine Dependency in Pancreatic Cancer

(2023)10.1158/0008-5472.c.6514022

N/A

0DataRank · unranked

0 citations

Yunzhan Li, Zekun Li, Shengchen Lin, Hongwei Wang, Jianwei Sun +11 more

eLife Assessment: SOD1 is a synthetic lethal target in PPM1D-mutant leukemia cells

(2023)10.7554/elife.91611.1.sa1

N/A

0DataRank · unranked

0 citations

Gina M. DeNicola

Connecting copper and cancer: from transition metal signalling to metalloplasia

Nature reviews. Cancer(2021)10.1038/s41568-021-00417-2

N/A

0DataRank · unranked

1289 citations

Ashley I. Bush, Angela Casini, Paul A. Cobine, Justin R. Cross, Gina M. DeNicola +19 more

Non-canonical glutamate-cysteine ligase activity protects against ferroptosis

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.29.123802

N/A

0DataRank · unranked

24 citations

Andrea Mockabee‐Macias, Chang Jiang, Isaac S. Harris, Gina M. DeNicola, Yun Pyo Kang

Mitochondrial respiratory function is preserved under cysteine starvation via glutathione catabolism in NSCLC

Nature Communications(2024)10.1038/s41467-024-48695-2

N/A

0DataRank · unranked

36 citations

Sang Jun Yoon, Tyce Flynn, Amanda M. Sherwood, Maddison A. Olley, Juliana Madej +2 more

An Activity-Based Sensing Approach to Multiplex Mapping of Labile Copper Pools by Stimulated Raman Scattering

Journal of the American Chemical Society(2024)10.1021/jacs.4c06296

N/A

0DataRank · unranked

23 citations

Elsy El Khoury, Aidan T. Pezacki, Naixin Qian, Miku Oi, Laura Torrente +6 more

A tandem activity-based sensing and labeling strategy reveals antioxidant response element regulation of labile iron pools

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2401579121

N/A

0DataRank · unranked

18 citations

Ryan L. Gonciarz, Toshitaka Okamura, Carson D. Matier, Laura Torrente, Ke Cheng +7 more

PHGDH supports liver ceramide synthesis and sustains lipid homeostasis

Cancer & Metabolism(2020)10.1186/s40170-020-00212-x

N/A

0DataRank · unranked

30 citations

Aimee Falzone, Min Liu, Paloma González‐Sánchez, Bo-Hyun Choi, Jonathan L. Coloff +4 more

PHGDH Induction by MAPK Is Essential for Melanoma Formation and Creates an Actionable Metabolic Vulnerability

Cancer Research(2024)10.1158/0008-5472.can-24-2471

N/A

0DataRank · unranked

8 citations

Xiaonan Xu, Benjamin Posorske, Yumi Kim, Kaizhen Wang, Olga Vera +4 more

Catabolism of extracellular glutathione supplies amino acids to support tumor growth

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.10.617667

N/A

0DataRank · unranked

3 citations

Marco Zocchi, Emily Tuttle, Nathan P. Ward, Bradley Smith, Yun Pyo Kang +20 more

MAPK-mediated PHGDH induction is essential for melanoma formation and represents an actionable vulnerability

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.11.589139

N/A

0DataRank · unranked

0 citations

Xiaonan Xu, Benjamin Posorske, Yumi Kim, Olga Vera, Kenneth Y. Tsai +3 more

Nicotinamide nucleotide transhydrogenase regulates mitochondrial metabolism in NSCLC through maintenance of Fe-S protein function

The Journal of Experimental Medicine(2020)10.1084/jem.20191689

N/A

0DataRank · unranked

54 citations

Yun Pyo Kang, Aimee Falzone, Theresa A. Boyle, Gina M. DeNicola, Nathan P. Ward

A histochemical approach to activity-based copper sensing reveals cuproplasia-dependent vulnerabilities in cancer

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2412816122

N/A

0DataRank · unranked

14 citations

Laura Torrente, Aidan T. Pezacki, Hanna I. Humpel, Erin L. Li, Sophia G. Miller +11 more

Distinct roles for the thioredoxin and glutathione antioxidant systems in Nrf2-Mediated lung tumor initiation and progression

Redox Biology(2025)10.1016/j.redox.2025.103653

N/A

0DataRank · unranked

11 citations

Basma A. Yasseen, Janine M. DeBlasi, Samantha Caldwell, Gina M. DeNicola, Amanda M. Sherwood

Best practices for cysteine analysis

Ferroptosis and Oxidative Stress(2025)10.70401/fos.2025.0010

N/A

0DataRank · unranked

1 citations

Gina M. DeNicola, Feroza K. Choudhury

A simple, anesthesia-free infusion technique for in vivo metabolic tracing

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.64898/2025.12.17.694756

N/A

0DataRank · unranked

0 citations

Samantha Caldwell, Matthew Long, Dominique Abrahams, Margi Baldwin, Gina M. DeNicola +1 more

Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone

Redox Biology(2020)10.1016/j.redox.2020.101440

N/A

0DataRank · unranked

46 citations

Nicolas Prieto-Farigua, Aimee Falzone, Cody Elkins, David A. Boothman, Eric B. Haura +2 more

Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer

Cancer Cell(2020)10.1016/j.ccell.2019.12.012

N/A

0DataRank · unranked

243 citations

Gina M. DeNicola, Colin Nixon, Karen Blyth, Christiaan F. Labuschagne, David A. Tuveson +2 more