Matthew D. Smith

Also affiliated with University of Michigan, Johns Hopkins Medicine

NeuroscienceMedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

2.4Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Associations ofsNfLwith clinico‐radiological measures in a largeMSpopulation

Annals of Clinical and Translational Neurology(2022)10.1002/acn3.51704

Top 9%

2.4DataRank

Top 9%41 citations

Kathryn C. Fitzgerald, Carol M. Singh, Matthew D. Smith, Maria Reyes‐Mantilla, Carrie M. Hersh +18 more

Papers

Driven by 44 papers — median percentile 91. Top paper: “Co-optimization of therapeutic antibody affinity and specificity using machine learning models that generalize to novel mutational space”.

Co-optimization of therapeutic antibody affinity and specificity using machine learning models that generalize to novel mutational space

Nature Communications(2022)10.1038/s41467-022-31457-3

N/A

4.2DataRank · unranked

160 citations

Patrick C. Kinnunen, Jie Huang, Lina Wu, Matthew D. Smith, Tiexin Wang +8 more

Associations ofsNfLwith clinico‐radiological measures in a largeMSpopulation

Annals of Clinical and Translational Neurology(2022)10.1002/acn3.51704

Top 9%

2.4DataRank

Top 9%41 citations

Kathryn C. Fitzgerald, Carol M. Singh, Matthew D. Smith, Maria Reyes‐Mantilla, Carrie M. Hersh +18 more

Engineered Multivalent Nanobodies Potently and Broadly Neutralize SARS‐CoV‐2 Variants

Advanced Therapeutics(2021)10.1002/adtp.202100099

N/A

1.3DataRank · unranked

44 citations

John S. Schardt, Alec A. Desai, Emily K. Makowski, Matthew D. Smith, Ghasidit Pornnoppadol +5 more

Reduction of therapeutic antibody self-association using yeast-display selections and machine learning

mAbs(2022)10.1080/19420862.2022.2146629

N/A

1.0DataRank · unranked

28 citations

Hongwei Chen, Matthew Lambert, Eric M. Bennett, Nicole S. Eschmann, Yulei Zhang +10 more

MHC class I and MHC class II reporter mice enable analysis of immune oligodendroglia in mouse models of multiple sclerosis

eLife(2023)10.7554/elife.82938

N/A

0.957DataRank · unranked

42 citations

Riley B Catenacci, Matthew D. Smith, Dongeun Heo, Cecilia E Miller, Keya R Meyers +4 more

Engineering the Live-Attenuated Polio Vaccine to Prevent Reversion to Virulence

Cell Host & Microbe(2020)10.1016/j.chom.2020.04.003

N/A

0.810DataRank · unranked

221 citations

Erika Bujáki, Patrick Dolan, Matthew D. Smith, Rahnuma Wahid, John Konz +8 more

Rational affinity maturation of anti-amyloid antibodies with high conformational and sequence specificity

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.100508

N/A

0.786DataRank · unranked

34 citations

Matthew D. Smith, Yulei Zhang, Emily K. Makowski, Julia E. Gerson, Edward Ionescu +9 more

Multi-omic evaluation of metabolic alterations in multiple sclerosis identifies shifts in aromatic amino acid metabolism

Cell Reports Medicine(2021)10.1016/j.xcrm.2021.100424

N/A

0.673DataRank · unranked

88 citations

Matthew D. Smith, Sol Kim, Elias S. Sotirchos, Michael D. Kornberg, Morgan Douglas +11 more

Intermittent calorie restriction alters T cell subsets and metabolic markers in people with multiple sclerosis

EBioMedicine(2022)10.1016/j.ebiom.2022.104124

N/A

0.631DataRank · unranked

66 citations

Pavan Bhargava, Matthew D. Smith, Diane Vizthum, Bobbie J. Henry-Barron, Michael D. Kornberg +7 more

Position-Specific Enrichment Ratio Matrix scores predict antibody variant properties from deep sequencing data

Bioinformatics(2023)10.1093/bioinformatics/btad446

N/A

0.573DataRank · unranked

10 citations

Marshall Case, Emily K. Makowski, Peter M. Tessier, Matthew D. Smith

Agonist antibody discovery: Experimental, computational, and rational engineering approaches

Drug Discovery Today(2021)10.1016/j.drudis.2021.09.008

N/A

0.510DataRank · unranked

29 citations

Harkamal S. Jhajj, Ryen L. O'Meara, Timon S. Lwo, Matthew D. Smith, Peter M. Tessier +1 more

Agreement Between Published Reference Resources for Neurofilament Light Chain Levels in People With Multiple Sclerosis

Neurology(2023)10.1212/wnl.0000000000207957

N/A

0.434DataRank · unranked

17 citations

Chen Hu, Matthew D. Smith, Hannah‐Noelle Lord, Anna DuVal, Georgina Arrambide +13 more

CEST MRI and MALDI imaging reveal metabolic alterations in the cervical lymph nodes of EAE mice

Journal of Neuroinflammation(2022)10.1186/s12974-022-02493-z

N/A

0.414DataRank · unranked

7 citations

Ethan Yang, Matthew D. Smith, Chengyan Chu, Peter A. Calabresi, Kristine Glunde +3 more

Myeloid lineage C3 induces reactive gliosis and neuronal stress during CNS inflammation

Nature Communications(2025)10.1038/s41467-025-58708-3

N/A

0.385DataRank · unranked

12 citations

Matthew D. Smith, Ajay Kesharwani, Marjan Gharagozloo, Sungtaek Oh, Chan Hyun Na +5 more

Restoring the Multiple Sclerosis Associated Imbalance of Gut Indole Metabolites Promotes Remyelination and Suppresses Neuroinflammation

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.27.620437

N/A

0.363DataRank · unranked

7 citations

Saumitra Sen Singh, Judy Lee, Asmita Dhukhwa, Fatemeh Siavoshi, Deepika Joshi +20 more

Characterization of spinal cord tissue-derived extracellular vesicles in neuroinflammation

Journal of Neuroinflammation(2024)10.1186/s12974-024-03147-y

N/A

0.330DataRank · unranked

8 citations

Ajay Kesharwani, Taekyung Ryu, Deepika Joshi, Dimitrios C. Ladakis, Matthew D. Smith +7 more

Accelerated Metabolomic Aging and Its Association with Social Determinants of Health in Multiple Sclerosis

medRxiv(2025)10.1101/2025.01.29.25321260

N/A

0.241DataRank · unranked

4 citations

Rezvan Noroozi, Gina Chang, Vinícius Andreoli Schoeps, Matthew D. Smith, Farren Briggs +7 more

Retinal pathology in spontaneous opticospinal experimental autoimmune encephalitis mice

Journal of Neuroimmunology(2022)10.1016/j.jneuroim.2022.577859

N/A

0.208DataRank · unranked

3 citations

Mark Shneyderman, Matthew D. Smith, Marjan Gharagozloo, Elias S. Sotirchos, Peter A. Calabresi +1 more

Quantitative flow cytometric selection of tau conformational nanobodies specific for pathological aggregates

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.13.540640

N/A

0DataRank · unranked

1 citations

Matthew D. Smith, Hanna Trzeciakiewicz, Mary E. Skinner, Sean P. Ferris, Emily K. Makowski +6 more

Human antibody polyreactivity is governed primarily by the heavy-chain complementarity-determining regions

Cell Reports(2024)10.1016/j.celrep.2024.114801

N/A

0DataRank · unranked

15 citations

Yulei Zhang, Jie Huang, Manali Sawant, Matthew D. Smith, Nandhini Rajagopal +8 more

Native ion mobility‐mass spectrometry reveals the binding mechanisms of anti‐amyloid therapeutic antibodies

Protein Science(2024)10.1002/pro.5008

N/A

0DataRank · unranked

6 citations

Alec A. Desai, Jennifer M. Zupancic, Matthew D. Smith, Peter M. Tessier, Brandon T. Ruotolo +1 more

The Immune Regulator NLRX1 Limits Inflammatory Neurodegeneration in the Anterior Visual Pathway

Neurology(2024)10.1212/01.wnl.0001051492.92479.e3

N/A

0DataRank · unranked

0 citations

Thomas Garton, Matthew D. Smith, Danny Galleguillos, Peter A. Calabresi, Marjan Gharagozloo +1 more

Bile acid metabolism is altered in multiple sclerosis and supplementation ameliorates neuroinflammation

Journal of Clinical Investigation(2020)10.1172/jci129401

N/A

0DataRank · unranked

232 citations

Matthew D. Smith, Leah Mische, Emily Harrington, Kathryn C. Fitzgerald, Kyle Martin +18 more

NLRX1 limits inflammatory neurodegeneration in the anterior visual pathway

Journal of Neuroinflammation(2025)10.1186/s12974-025-03339-0

N/A

0DataRank · unranked

5 citations

Matthew D. Smith, Danny Galleguillos, Thomas Garton, Jackson W. Mace, Sachin P. Gadani +11 more

Early control of cochlear viral load limits cochlear inflammation and prevents virus-induced sensorineural hearing loss

Journal of Neuroinflammation(2025)10.1186/s12974-025-03416-4

N/A

0DataRank · unranked

4 citations

Maria C. Seleme, Tatiana T. Marquez‐Lago, Jiung-Wen Chen, Michael Mach, William J. Britt +1 more

Directed evolution of drug-like Aβ conformation-specific antibodies

Frontiers in Immunology(2025)10.3389/fimmu.2025.1655893

N/A

0DataRank · unranked

1 citations

Matthew D. Smith, Jennifer M. Zupancic, Emily K. Makowski, Yulei Zhang, Julia E. Gerson +8 more

Real‐world clinical experience with serum MOG and AQP4 antibody testing by live versus fixed cell‐based assay

Annals of Clinical and Translational Neurology(2025)10.1002/acn3.52310

N/A

0DataRank · unranked

36 citations

Angeliki Filippatou, Conlan Tran, LuAnn Rezavi, Kai Guo, Matthew D. Smith +8 more

Diffusion‐time dependence of diffusional kurtosis in the mouse brain

Magnetic Resonance in Medicine(2020)10.1002/mrm.28189

N/A

0DataRank · unranked

64 citations

Matthew D. Smith, Peter A. Calabresi, Manisha Aggarwal

iPSCs from people with MS can differentiate into oligodendrocytes in a homeostatic but not an inflammatory milieu

PLoS ONE(2020)10.1371/journal.pone.0233980

N/A

0DataRank · unranked

39 citations

Matthew D. Smith, Labchan Rajbhandari, Linzhao Cheng, Yongxing Gao, Vasiliki Mahairaki +5 more

Inhibition of neutral sphingomyelinase 2 promotes remyelination

Science Advances(2020)10.1126/sciadv.aba5210

N/A

0DataRank · unranked

37 citations

Amit Agarwal, Matthew D. Smith, Saja S. Khuder, Emily G. Baxi, Ajit G. Thomas +7 more

A lymphocyte–microglia–astrocyte axis in chronic active multiple sclerosis

Nature(2021)10.1038/s41586-021-03892-7

N/A

0DataRank · unranked

768 citations

Dragan Maric, Marjan Gharagozloo, Thomas Garton, Matthew D. Smith, Jing Jin +11 more

Discordant humoral and T cell immune responses to SARS-CoV-2 vaccination in people with multiple sclerosis on anti-CD20 therapy

EBioMedicine(2021)10.1016/j.ebiom.2021.103636

N/A

0DataRank · unranked

115 citations

Maria Reyes‐Mantilla, Larissa Jank, Samantha Harris, Morgan Douglas, Matthew D. Smith +5 more

Single-cell transcriptomic reveals molecular diversity and developmental heterogeneity of human stem cell-derived oligodendrocyte lineage cells

Nature Communications(2021)10.1038/s41467-021-20892-3

N/A

0DataRank · unranked

108 citations

Alyssa Kallman, Weixiang Fang, Cynthia Berlinicke, Joseph Mertz, Prajwal Devkota +13 more

Complement component 3 from astrocytes mediates retinal ganglion cell loss during neuroinflammation

Acta Neuropathologica(2021)10.1007/s00401-021-02366-4

N/A

0DataRank · unranked

96 citations

Matthew D. Smith, Jing Jin, Thomas Garton, Michelle Taylor, Alyssa Chao +12 more

Directed evolution of potent neutralizing nanobodies against SARS-CoV-2 using CDR-swapping mutagenesis

Cell chemical biology(2021)10.1016/j.chembiol.2021.05.019

N/A

0DataRank · unranked

59 citations

Alec A. Desai, John S. Schardt, Ghasidit Pornnoppadol, Emily K. Makowski, Matthew D. Smith +7 more

Discovery and characterization of high-affinity, potent SARS-CoV-2 neutralizing antibodies via single B cell screening

Scientific Reports(2021)10.1038/s41598-021-99401-x

N/A

0DataRank · unranked

25 citations

Ghasidit Pornnoppadol, Alec A. Desai, Kyung Soo Park, Jennifer M. Zupancic, Emily K. Makowski +8 more

Discordant humoral and T cell immune responses to SARS-CoV-2 vaccination in people with multiple sclerosis on anti-CD20 therapy

medRxiv(2021)10.1101/2021.08.23.21262472

N/A

0DataRank · unranked

15 citations

Maria Reyes‐Mantilla, Larissa Jank, Samantha Harris, Morgan Douglas, Matthew D. Smith +5 more

Mutational analysis of SARS-CoV-2 variants of concern reveals key tradeoffs between receptor affinity and antibody escape

PLoS Computational Biology(2022)10.1371/journal.pcbi.1010160

N/A

0DataRank · unranked

22 citations

John S. Schardt, Matthew D. Smith, Peter M. Tessier, Emily K. Makowski

Intermittent calorie restriction alters T cell subsets and metabolic markers in people with multiple sclerosis

medRxiv(2022)10.1101/2022.01.11.22269094

N/A

0DataRank · unranked

4 citations

Pavan Bhargava, Matthew D. Smith, Diane Vizthum, Bobbie J. Henry-Barron, Michael D. Kornberg +7 more

Inhibition of neutral sphingomyelinase 2 impairs HIV-1 envelope formation and substantially delays or eliminates viral rebound

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2219543120

N/A

0DataRank · unranked

18 citations

Abdül Waheed, Pragney Deme, Şehmus Tohumeken, Rana Rais, Matthew D. Smith +7 more

Quantitative flow cytometric selection of tau conformational nanobodies specific for pathological aggregates

Frontiers in Immunology(2023)10.3389/fimmu.2023.1164080

N/A

0DataRank · unranked

11 citations

Matthew D. Smith, Hanna Trzeciakiewicz, Mary E. Skinner, Sean P. Ferris, Emily K. Makowski +6 more

Flow cytometric isolation of drug-like conformational antibodies specific for amyloid fibrils

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.04.547698

N/A

0DataRank · unranked

5 citations

Jennifer M. Zupancic, Hanna Trzeciakiewicz, Julia E. Gerson, Kelly N. Dubois, Mary E. Skinner +14 more

PKC modulator bryostatin-1 therapeutically targets CNS innate immunity to attenuate neuroinflammation and promote remyelination

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.28.555084

N/A

0DataRank · unranked

4 citations

Efrat Abramson, Shruthi Shanmukha, Matthew D. Smith, Wesley H. Godfrey, Judy J. Lee +11 more

Position-Specific Enrichment Ratio Matrix scores predict antibody variant properties from deep sequencing data

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.10.548448

N/A

0DataRank · unranked

2 citations

Marshall Case, Emily K. Makowski, Peter M. Tessier, Matthew D. Smith

Matthew D. Smith

Indexed papers

Top data-sharing exemplar

Papers