Ayellet V. Segrè

Also affiliated with Massachusetts Eye and Ear Infirmary, Harvard University

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

48.0Author DataRank

Indexed papers

15in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 15 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Genetic effects on gene expression across human tissues

Nature(2017)10.1038/nature24277

Top 1%

10.1DataRank

Top 1%4706 citations

Barbara E. Engelhardt, Stephen B. Montgomery, Sara Mostafavi, Ayellet V. Segrè, Hailei Zhang +227 more

Papers

Driven by 54 papers — median percentile 92. Top paper: “Correction: Corrigendum: Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases”.

Correction: Corrigendum: Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases

Scientific Reports(2016)10.1038/srep19384

N/A

10.4DataRank · unranked

722 citations

Tao Huang, Francesca Petralia, Quan Long, Bin Zhang, Carmen Argmann +129 more

Cell type–specific genetic regulation of gene expression across human tissues

Science(2020)10.1126/science.aaz8528

N/A

10.3DataRank · unranked

596 citations

François Aguet, Meritxell Oliva, Manuel Muñoz-Aguirre, Silva Kasela, Valentin Wucher +77 more

Genetic effects on gene expression across human tissues

Nature(2017)10.1038/nature24277

Top 1%

10.1DataRank

Top 1%4706 citations

Barbara E. Engelhardt, Stephen B. Montgomery, Sara Mostafavi, Ayellet V. Segrè, Hailei Zhang +227 more

The impact of sex on gene expression across human tissues

Science(2020)10.1126/science.aba3066

N/A

9.0DataRank · unranked

727 citations

Manuel Muñoz-Aguirre, Sarah Kim-Hellmuth, Valentin Wucher, Ariel DH Gewirtz, Daniel J. Cotter +72 more

Determinants of telomere length across human tissues

Science(2020)10.1126/science.aaz6876

N/A

8.6DataRank · unranked

501 citations

Farzana Jasmine, Lin Chen, Meytal Chernoff, Tong Lin, Dayana Delgado +90 more

The GTEx Consortium atlas of genetic regulatory effects across human tissues

Science(2020)10.1126/science.aaz1776

Top 2%

8.0DataRank

Top 2%5930 citations

Shankara Anand, Kristin G. Ardlie, Stacey Gabriel, Gad Getz, Aaron Graubert +95 more

Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia

Nature Genetics(2020)10.1038/s41588-020-0599-0

N/A

7.8DataRank · unranked

354 citations

Hélène Choquet, Anthony Khawaja, Robert Wojciechowski, Milly Tedja, Jie Yin +22 more

Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation

Nature Genetics(2018)10.1038/s41588-018-0154-4

Top 3%

6.3DataRank

Top 3%492 citations

Eric R. Gamazon, Ayellet V. Segrè, Martijn van de Bunt, Xiaoquan Wen, Emilio Rodríguez-Ruiz +14 more

Pan-cancer analysis of whole genomes

Nature(2020)10.1038/s41586-020-1969-6

Top 3%

5.9DataRank

Top 3%3307 citations

Lauri A. Aaltonen, Federico Abascal, Adam Abeshouse, Hiroyuki Aburatani, David J. Adams +1244 more

A Quantitative Proteome Map of the Human Body

Cell(2020)10.1016/j.cell.2020.08.036

Top 4%

5.1DataRank

Top 4%487 citations

Meng Wang, Shin Lin, Ruiqi Jian, Xiao Li, Joanne Chan +95 more

Transcriptomic signatures across human tissues identify functional rare genetic variation

Science(2020)10.1126/science.aaz5900

N/A

5.0DataRank · unranked

166 citations

Benjamin J. Strober, Jonah Einson, Nathan S. Abell, François Aguet, Alvaro N. Barbeira +183 more

Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

Nature(2020)10.1038/s41586-020-1965-x

Top 5%

4.6DataRank

Top 5%668 citations

Federico Abascal, Jeremiah A. Wala, Ofer Shapira, Grace Tiao, Henrik Hornshøj +1240 more

A vast resource of allelic expression data spanning human tissues

Genome Biology(2020)10.1186/s13059-020-02122-z

Top 8%

2.7DataRank

Top 8%147 citations

François Aguet, Pejman Mohammadi, Kristin G. Ardlie, Anthony Philippakis, Leanne Haggerty +159 more

Genetic effects on gene expression across human tissues

UNC Libraries(2020)10.17615/p82n-gb73

Top 8%

2.6DataRank

Top 8%63 citations

Yuan He, Lin Chen, Emmanouil T. Dermitzakis, Philip A. Branton, Andrew B. Nobel +95 more

Single-nucleus cross-tissue molecular reference maps to decipher disease gene function

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.19.452954

Top 16%

1.3DataRank

Top 16%27 citations

Eugene Drokhlyansky, Shankara Anand, Ayshwarya Subramanian, Evgenij Fiskin, Michal Slyper +19 more

Germline determinants of the somatic mutation landscape in 2,642 cancer genomes

bioRxiv (Cold Spring Harbor Laboratory)(2017)10.1101/208330

Top 17%

1.2DataRank

Top 17%26 citations

Grace Tiao, Bin Zhu, Tobias Rausch, Francesc Muyas, Alan J. Robertson +108 more

Integrating genetic regulation and single-cell expression with GWAS prioritizes causal genes and cell types for glaucoma

Nature Communications(2024)10.1038/s41467-023-44380-y

N/A

1.0DataRank · unranked

64 citations

Wenjun Yan, John M. Rouhana, Aboozar Monovarfeshani, Xinyi Jiang, Puja A. Mehta +65 more

Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries

Nature Communications(2021)10.1038/s41467-020-20851-4

N/A

0.933DataRank · unranked

503 citations

Eric Jorgenson, Pirro G. Hysi, Anthony Khawaja, Sarah A. Pendergrass, Xikun Han +93 more

Effect of predicted protein-truncating genetic variants on the human transcriptome

Science(2015)10.1126/science.1261877

N/A

0.877DataRank · unranked

345 citations

Matti Pirinen, Donald F. Conrad, Monkol Lek, Emily K. Tsang, Konrad J. Karczewski +206 more

Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases

Scientific Reports(2015)10.1038/srep15145

N/A

0.811DataRank · unranked

222 citations

Tao Huang, Francesca Petralia, Quan Long, Bin Zhang, Carmen Argmann +128 more

Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease

Cell(2021)10.1016/j.cell.2021.03.050

N/A

0.804DataRank · unranked

212 citations

Daniel C. Nachun, Nicole M. Ferraro, Michael J. Gloudemans, Abhiram S. Rao, Craig Smail +168 more

Large-scale multitrait genome-wide association analyses identify hundreds of glaucoma risk loci

Nature Genetics(2023)10.1038/s41588-023-01428-5

N/A

0.755DataRank · unranked

152 citations

Puya Gharahkhani, Andrew R. Hamel, Jue‐Sheng Ong, Miguel E. Rentería, Puja A. Mehta +24 more

Genome-wide meta-analysis identifies 22 loci for normal tension glaucoma with significant overlap with high tension glaucoma

Nature Communications(2024)10.1038/s41467-024-54301-2

N/A

0.704DataRank · unranked

15 citations

Weixiong He, Regina Yu, Xikun Han, Andrew R. Hamel, Terri L. Young +28 more

Characteristics of p.Gln368Ter Myocilin Variant and Influence of Polygenic Risk on Glaucoma Penetrance in the UK Biobank

Ophthalmology(2021)10.1016/j.ophtha.2021.03.007

N/A

0.604DataRank · unranked

55 citations

Sayuri Sekimitsu, Jiali Wang, Tobias Elze, Puya Gharahkhani, Brian Cole +36 more

A large cross-ancestry meta-analysis of genome-wide association studies identifies 69 novel risk loci for primary open-angle glaucoma and includes a genetic link with Alzheimer’s disease

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.30.927822

N/A

0.416DataRank · unranked

15 citations

Eric Jorgenson, Pirro G. Hysi, Anthony Khawaja, Sarah A. Pendergrass, Xikun Han +73 more

Integrative analysis of single-cell transcriptomics and genetic associations identify cell states associated with vascular disease

Atherosclerosis(2025)10.1016/j.atherosclerosis.2025.119108

N/A

0.208DataRank · unranked

3 citations

William Schwartzman, Shi Fang, Shamsudheen Karuthedath Vellarikkal, Deepak Atri, Ankith Reddy +6 more

Author Correction: Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

Communications Biology(2022)10.1038/s42003-022-03769-z

N/A

0.165DataRank · unranked

2 citations

Lars Feuerbach, Chen Hong, David Mas-Ponte, Randi Istrup Pedersen, PCAWG Drivers and Functional Interpretation Group +1255 more

Deep-learning-derived glaucoma-related endophenotypes enable novel genome-wide genetic and functional discovery

medRxiv(2025)10.1101/2025.11.04.25339517

N/A

0.165DataRank · unranked

2 citations

Ivy Yan Zhao, Saber Kazeminasab Hashemabad, Tobias Elze, Mohammad Eslami, Mengyu Wang +4 more

Gene Set Enrichment Analsyes Identify Pathways Involved in Genetic Risk for Diabetic Retinopathy

American Journal of Ophthalmology(2021)10.1016/j.ajo.2021.06.014

N/A

0DataRank · unranked

13 citations

Gayatri Susarla, Lynn K. Stanwyck, John M. Rouhana, Ashley Li, Samuela Pollack +25 more

Data used in ECLIPSER methods paper and GTEx snRNA-seq cross-tissue reference map analysis

Zenodo (CERN European Organization for Nuclear Research)(2021)10.5281/zenodo.5725802

Top 100%

0DataRank

Top 100%0 citations

Jiali Wang, Gökçen Eraslan, Duyen T. Nguyen, Andrew R. Hamel, Brian Cole +5 more

ECLIPSER: identifying causal cell types and genes for complex traits through single cell enrichment of e/sQTL-mapped genes in GWAS loci

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.24.469720

N/A

0DataRank · unranked

12 citations

Jiali Wang, Gökçen Eraslan, Shankara Anand, Andrew R. Hamel, Brian Cole +5 more

Photoreceptor layer thinning is an early biomarker for age-related macular degeneration development: Epidemiological and genetic evidence from UK Biobank optical coherence tomography data

medRxiv(2021)10.1101/2021.08.18.21262226

N/A

0DataRank · unranked

1 citations

Sayuri Sekimitsu, Yixuan Ye, Vineet K. Raghu, Luca Pinello, Tobias Elze +7 more

Photoreceptor Layer Thinning Is an Early Biomarker for Age-Related Macular Degeneration

Ophthalmology(2022)10.1016/j.ophtha.2022.02.001

N/A

0DataRank · unranked

78 citations

Sayuri Sekimitsu, Yixuan Ye, Vineet K. Raghu, Luca Pinello, Tobias Elze +7 more

Interaction of background genetic risk, psychotropic medications, and primary angle closure glaucoma in the UK Biobank

PLoS ONE(2022)10.1371/journal.pone.0270530

N/A

0DataRank · unranked

7 citations

Jiali Wang, Tobias Elze, Ayellet V. Segrè, Janey L. Wiggs, Nazlee Zebardast +1 more

Integrating genetic regulation and single-cell expression with GWAS prioritizes causal genes and cell types for glaucoma

medRxiv(2022)10.1101/2022.05.14.22275022

N/A

0DataRank · unranked

58 citations

Wenjun Yan, John M. Rouhana, Aboozar Monovarfeshani, Xinyi Jiang, Puja A. Mehta +20 more

Data used in ECLIPSER methods paper and GTEx snRNA-seq cross-tissue reference map analysis

Zenodo (CERN European Organization for Nuclear Research)(2021)10.5281/zenodo.6402401

Top 100%

0DataRank

Top 100%0 citations

Jiali Wang, Gökçen Eraslan, Duyen T. Nguyen, Andrew R. Hamel, Brian Cole +5 more

Association of retinal optical coherence tomography metrics and polygenic risk scores with cognitive function and future cognitive decline

British Journal of Ophthalmology(2023)10.1136/bjo-2022-322762

N/A

0DataRank · unranked

15 citations

Yusrah Shweikh, Sarah Shareef, Yan Zhao, Tobias Elze, Ayellet V. Segrè +3 more

QTL mapping of human retina DNA methylation identifies 87 gene-epigenome interactions in age-related macular degeneration

Research Square(2023)10.21203/rs.3.rs-3011096/v1

N/A

0DataRank · unranked

5 citations

Puja A. Mehta, Andrew R. Hamel, Sudeep Mahrotra, Christina Kiel, Tobias Strunz +12 more

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

UNC Libraries(2020)10.17615/3we9-ae42

Top 100%

0DataRank

Top 100%0 citations

David S. DeLuca, Ayellet V. Segrè, Timothy J. Sullivan, Timothy R. Young, Ellen T. Gelfand +27 more

QTL mapping of human retina DNA methylation identifies 87 gene-epigenome interactions in age-related macular degeneration

Nature Communications(2024)10.1038/s41467-024-46063-8

N/A

0DataRank · unranked

46 citations

Puja A. Mehta, Andrew R. Hamel, Sudeep Mehrotra, Christina Kiel, Tobias Strunz +12 more

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

UNC Libraries(2020)10.17615/2bje-6g29

N/A

0DataRank · unranked

0 citations

Deborah J. Thompson, Hannes Helgason, Timothy M. Frayling, Hilary K. Finucane, Patrick Sulem +211 more

Use of Diagnostic Codes for Primary Open-Angle Glaucoma Polygenic Risk Score Construction in Electronic Health Record–Linked Biobanks

American Journal of Ophthalmology(2024)10.1016/j.ajo.2024.06.007

N/A

0DataRank · unranked

10 citations

Joyce Kang, Elaine Han, Urvi Gupta, Kasem Seresirikachorn, Ha My T. Vy +12 more

Machine Learning–Derived Baseline Visual Field Patterns Predict Future Glaucoma Onset in the Ocular Hypertension Treatment Study

Investigative Ophthalmology & Visual Science(2024)10.1167/iovs.65.2.35

N/A

0DataRank · unranked

9 citations

Sophie Smith, John H. Fingert, Mae O. Gordon, Michael A. Kass, Todd E. Scheetz +5 more

Independent Effects of Blood Pressure on Intraocular Pressure and Retinal Ganglion Cell Degeneration: A Mendelian Randomization Study

Investigative Ophthalmology & Visual Science(2024)10.1167/iovs.65.8.35

N/A

0DataRank · unranked

6 citations

Ayellet V. Segrè, Dipender Gill, Benjamin Woolf, Seyedeh M. Zekavat, Stephen Burgess +4 more

Glaucoma-Protective Human Single-Nucleotide Polymorphism in the Angpt2 Locus Increased ANGPT2 Expression and Schlemm Canal Area in Mice—Brief Report

Arteriosclerosis Thrombosis and Vascular Biology(2024)10.1161/atvbaha.124.321555

N/A

0DataRank · unranked

3 citations

Tuncer Onay, Phoebe Leeaw, Pan Liu, Dilip K. Deb, Benjamin R. Thomson +4 more

Author Correction: Combined burden and functional impact tests for cancer driver discovery using DriverPower

Nature Communications(2022)10.1038/s41467-022-32343-8

N/A

0DataRank · unranked

0 citations

PCAWG Drivers and Functional Interpretation Working Group, Federico Abascal, Samirkumar B. Amin, Pratiti Bandopadhayay, Rameen Beroukhim +1242 more

Does Age Modify the Relation Between Genetic Predisposition to Glaucoma and Various Glaucoma Traits in the UK Biobank?

Investigative Ophthalmology & Visual Science(2025)10.1167/iovs.66.2.57

N/A

0DataRank · unranked

3 citations

Jae H. Kang, Janey L. Wiggs, Hetince Zhao, Keva Li, Nazlee Zebardast +7 more

Polygenic Risk Prediction for Normal-Tension Glaucoma

Investigative Ophthalmology & Visual Science(2025)10.1167/iovs.66.9.4

N/A

0DataRank · unranked

2 citations

Santiago Díaz‐Torres, Regina Yu, Weixiong He, David A. Mackey, Ayellet V. Segrè +4 more

Pyruvate and related energetic metabolites modulate resilience against high genetic risk for glaucoma

eLife(2025)10.7554/elife.105576

N/A

0DataRank · unranked

9 citations

Nicholas Tolman, Ayellet V. Segrè, Kelsey V. Stuart, Oana A. Zeleznik, Neeru A. Vallabh +14 more

Dual-Level Pattern Tree for Visual Field Improves Glaucoma Progression and Polygenic Risk Prediction

Translational Vision Science & Technology(2025)10.1167/tvst.14.12.11

Top 100%

0DataRank

Top 100%0 citations

Lucy Q. Shen, Louis R. Pasquale, Michael V. Boland, Sarah R. Wellik, Carlos Gustavo De Moraes +10 more

REECAP: Contrastive learning of retinal aging reveals genetic loci linking morphology to eye disease

medRxiv(2025)10.1101/2025.11.19.25340555

N/A

0DataRank · unranked

1 citations

Daniel Sens, Ayshan Aliyeva, Shubham Chaudhary, Qiang Xu, Emmanuelle Salin +10 more

Author response: Pyruvate and Related Energetic Metabolites Modulate Resilience Against High Genetic Risk for Glaucoma

(2025)10.7554/elife.105576.2.sa0

N/A

0DataRank · unranked

0 citations

Nicholas Tolman, Ayellet V. Segrè, Kelsey V. Stuart, Oana A. Zeleznik, Neeru A. Vallabh +14 more

Paired DNA and RNA sequencing uncovers common and rare genetic variants regulating gene expression in the human retina

medRxiv(2025)10.1101/2025.04.25.25326445

N/A

0DataRank · unranked

0 citations

Ayellet V. Segrè, Kinga M. Bujakowska, Steve Haynes, Diana Baralle, Siddharth Banka +4 more

Data used in ECLIPSER methods paper and GTEx snRNA-seq cross-tissue reference map analysis

Zenodo (CERN European Organization for Nuclear Research)(2021)10.5281/zenodo.5725801

Top 100%

0DataRank

Top 100%0 citations

Jiali Wang, Gökçen Eraslan, Duyen T. Nguyen, Andrew R. Hamel, Brian Cole +5 more

Ayellet V. Segrè

Indexed papers

Top data-sharing exemplar

Papers