Genetic effects on gene expression across human tissues is a dataset published in Nature (2017). On theSindex it has a DataRank of 10.1, placing it in the top 1.3% of the data-sharing corpus. It has been cited 4,706 times, with 100 citing works in its 1-hop citation network. Its calibrated FAIR score is 71/100.
Ranks in the top 1% for downstream scientific impact
Linked data & code
DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?
FAIR checklist signals are shown for context only and do not affect DataRank scoring.
Full FAIR picture · advisory
The headline score is computed from the scored criteria — the fact-shaped checks (a repository, an accession, a licence) that two independent models agree on. The advisory criteria below are real FAIR guidance but rest on judgment calls that models read differently, so they inform without moving the number.
“All data are available from dbGaP (accession phs000424.v6.p1)”
The paper provides a dbGaP accession (phs000424.v6.p1), which is a persistent identifier scheme. [majority verdict 'yes' (4/5 passes agreed)]
RDA-F1-01D — FAIR Data Maturity Model: 'Data is identified by a persistent identifier' (priorit · RDA-F1-02D — FAIR Data Maturity Model: 'Data is identified by a globally unique identifier' · FsF-F1-02D — F-UJI/FAIRsFAIR: 'Data is assigned a persistent identifier'
“All data are available from dbGaP (accession phs000424.v6.p1)”
The paper names dbGaP, a data repository listed in re3data, as the holder of the data. [majority verdict 'yes' (4/5 passes agreed)]
RDA-F4-01M — FAIR Data Maturity Model: metadata is offered so it can be harvested and indexed ( · NIH DMS Policy Element 4 (NOT-OD-21-014) — name the repository where data will be archived · NSTC Desirable Characteristics of Data Repositories (2022) — 'Long-Term Sustainability', 'Reten
“All data are available from dbGaP (accession phs000424.v6.p1)”
The dataset identifier (phs000424.v6.p1) appears only in the body text, not in a reference-list entry. [majority verdict 'partial' (4/5 passes agreed)]
FORCE11 Joint Declaration of Data Citation Principles (2014) — data should be cited as a first- · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes · FsF-F3-01M — F-UJI: 'Metadata includes the identifier of the data it describes'
Advisory · not in the published score
“All data are available from dbGaP (accession phs000424.v6.p1) with multiple data views publicly available from the GTEx Portal ( www.gtexportal.org ).”
The data availability statement names a repository (dbGaP) and provides an accession, corresponding to Colavizza category 3. [majority verdict 'yes' (3/5 passes agreed)]
Colavizza, Hrynaszkiewicz, Staden, Whitaker & McGillivray (2020), 'The citation advantage of li · Springer Nature research data policy — Data Availability Statements: standard statement templat · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes
“A total of 7,051 samples from 449 donors represent the GTEx v6p analysis freeze ( Fig. 1a ; Supplementary Information 1–5 ; Supplementary Figs 1–6 ; Supplementary Tables 1–10 ).”
The dataset's content is described in running prose, not in a dedicated section, table, or enumerated list.
RDA-F2-01M — 'Rich metadata is provided to allow discovery' (priority Essential) · FsF-F2-01M — F-UJI: 'Metadata includes descriptive core elements to support data findability' · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data'
“summary-level expression data and eQTLs across all tissues are available from the GTEx Portal (www.gtexportal.org)”— not found in the paper; verdict downgraded
The GTEx Portal provides summary data without any precondition, making them openly accessible. [downgraded to 'partial' — no verifiable quote from the paper] [majority verdict 'partial' (3/5 passes agreed)]
RDA-A1.1-01D — 'Data is accessible through a free access protocol' · FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · NSTC Desirable Characteristics of Data Repositories (2022) — 'Free and Easy Access'
Advisory · not in the published score
“multiple data views publicly available from the GTEx Portal ( www.gtexportal.org )”
The paper explicitly labels the data as 'publicly available' in the text. [majority verdict 'yes' (4/5 passes agreed)]
FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · RDA-A1-01M — metadata contains information to enable the user to get access to the data · COAR Controlled Vocabularies — Access Rights v1.0 (open / embargoed / restricted / metadata-onl
“Genotype data from the GTEx v6p release are available in dbGaP (study accession phs000424.v6.p1)”— not found in the paper; verdict downgraded
The paper names dbGaP, a controlled-access repository with an institutional Data Access Committee, as the gatekeeper for raw data. [downgraded to 'partial' — no verifiable quote from the paper] [majority verdict 'partial' (2/5 passes agreed)]
NIH Genomic Data Sharing Policy (NOT-OD-14-124) — controlled-access via a Data Access Committee · RDA-A1.2-01D — 'Data is accessible through an access protocol that supports authentication and · NIH DMS Policy Element 5 (NOT-OD-21-014) — Access, Distribution, or Reuse Considerations (conse
The paper does not state how long the data will be retained or made available; no persistence commitment or availability timing is mentioned. [majority verdict 'no' (3/5 passes agreed)]
NIH DMS Plan Element 4 (NOT-OD-21-014) — Data Preservation, Access, and Associated Timelines · NSTC Desirable Characteristics (2022), Organizational Infrastructure: 'Retention Policy' · RDA-A2-01M — 'Metadata is guaranteed to remain available after data is no longer available'
“The VCFs for the imputed array data are available through dgGAP, in phg000520.v2.GTEx MidPoint Imputation.genotype-calls-vcf.c1.GRU.tar (the archive contains a VCF for chromosomes 1–22 and a VCF for chromosome X).”
The paper mentions VCF (Variant Call Format), an open, non-proprietary format. [majority verdict 'yes' (3/5 passes agreed)]
FsF-R1.3-02D — F-UJI: 'Data is available in a file format recommended by the target research co · RDA-R1.3-02D — data is expressed in a machine-understandable community standard · RDA-I1-01D — data uses a knowledge representation expressed in a standardised format
Advisory · not in the published score
“GENCODE v19”— not found in the paper; verdict downgraded
GENCODE is a community standard for gene annotation, used in the data generation. [downgraded to 'partial' — no verifiable quote from the paper] [majority verdict 'partial' (2/5 passes agreed)]
RDA-R1.3-01M — 'Metadata complies with a community standard' (priority Essential) · RDA-R1.3-01D — 'Data complies with a community standard' · RDA-I2-01M — '(Meta)data use vocabularies that follow FAIR principles'
The paper does not provide an identifier (accession, DOI, RRID) for any external resource such as the 1000 Genomes reference panel or other databases; only names and references are given. [majority verdict 'no' (3/5 passes agreed)]
RDA-I3-01M — '(meta)data include references to other (meta)data' · RDA-I3-03M — 'metadata includes qualified references to other metadata' · FsF-I3-01M — F-UJI: 'Metadata includes links between the data and its related entities'
The paper does not attach a license to the data; the CC BY 4.0 license refers to the article, not the dataset.
RDA-R1.1-01M — 'Metadata includes information about the licence under which the data can be reu · RDA-R1.1-02M — 'Metadata refers to a standard reuse licence' · RDA-R1.1-03M — 'Metadata refers to a machine-understandable reuse licence'
“All data are available from dbGaP (accession phs000424.v6.p1)”
The accession contains a version token (v6.p1), and the paper refers to the 'GTEx v6p release'. [majority verdict 'yes' (3/5 passes agreed)]
DataCite Metadata Schema 4.6 — the 'Version' property · RDA-R1.2-01M — provenance information (which version was used is provenance) · NSTC Desirable Characteristics of Data Repositories (2022) — 'Provenance', 'Retention Policy'
“Software used to process the RNA-seq, genotypes, cis -eQTLs, and ASE is available at: https://github.com/broadinstitute/gtex-pipeline”
The paper gives a GitHub URL, a machine-resolvable locator for the study's own code. [majority verdict 'yes' (3/5 passes agreed)]
NIH DMS Policy Element 2 (NOT-OD-21-014) — 'Related Tools, Software and/or Code' · FAIR4RS Principles v1.0 (Chue Hong et al., 2022; RDA/FORCE11/ReSA) — FAIR Principles for Resear · FORCE11 Software Citation Principles (Smith, Katz & Niemeyer, 2016, PeerJ CS 2:e86)
“R01MH109905”
The paper includes specific grant numbers for funding. [majority verdict 'yes' (4/5 passes agreed)]
DataCite Metadata Schema 4.6 — 'FundingReference' property (funderName, funderIdentifier, award · Crossref Funder Registry — canonical funder identifiers for funding metadata · RDA-F2-01M — rich metadata provided to allow discovery (funding is part of the descriptive reco
Advisory · not in the published score
“Non-strand specific, polyA + selected RNA-seq libraries were generated using the Illumina TruSeq protocol.”
The paper names specific instruments and kits (Illumina TruSeq, Illumina Human Omni Beadchips) and software (TopHat, SHAPEIT2, IMPUTE2). [majority verdict 'yes' (4/5 passes agreed)]
RDA-R1.2-01M — 'Metadata includes provenance information according to community- specific standa · FsF-R1.2-01M — F-UJI: 'Metadata includes provenance information about data creation or generati · W3C PROV-O (W3C Recommendation, 2013) — the entity/activity/agent model of provenance
“Supplementary Tables 1–10”
Variable definitions are provided inside the article as supplementary tables, not as a separate documentation object shipped with the data. [majority verdict 'partial' (3/5 passes agreed)]
RDA-R1-01M — '(Meta)data are richly described with a plurality of accurate and relevant attribu · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data' · NIH DMS Policy Element 3 (NOT-OD-21-014) — Standards (documentation and metadata to accompany t
Calibrated FAIR score — a parallel quality metric, independent of the DataRank citation score. See the full evaluation →
Base Score Contribution
1.3
From this paper's citation signal
Citation Network Contribution
8.8
From 100 citing papers with measurable signal
Ranked by each citer's contribution to N(p) — log1p(Cq) divided by its reference count — out of 100 citers.
NHLBI NIH HHS
Grant: HHSN268201000002C
NHLBI NIH HHS
Grant: HHSN268201000009C
National Institute for Health Research (NIHR)
Grant: NF-SI-0611-10099
NIMH NIH HHS
Grant: R01 MH101814
NIDDK NIH HHS
Grant: U54 DK105566
NHGRI NIH HHS
Grant: K22 HG000044
NIMH NIH HHS
Grant: R01 MH101782
NIMH NIH HHS
Grant: R01 MH101810
NIMH NIH HHS
Grant: R01 MH106842
NLM NIH HHS
Grant: T15 LM007033
NHGRI NIH HHS
Grant: U41 HG002371
NCI NIH HHS
Grant: HHSN261200800001E
NIA NIH HHS
Grant: P30 AG010124
NIGMS NIH HHS
Grant: R01 GM104371
NHGRI NIH HHS
Grant: R01 HG008150
NHGRI NIH HHS
Grant: R01 HG009125
NIMH NIH HHS
Grant: R01 MH101819
NHGRI NIH HHS
Grant: U01 HG009080
NIMH NIH HHS
Grant: R01 MH090937
NIMH NIH HHS
Grant: R01 MH109905
NHGRI NIH HHS
Grant: U01 HG007436
NHGRI NIH HHS
Grant: U54 HG007990
NHGRI NIH HHS
Grant: UM1 HG008901
NHLBI NIH HHS
Grant: HHSN268201000029C
NIDA NIH HHS
Grant: R01 DA006227
NHGRI NIH HHS
Grant: U01 HG007591
NIMH NIH HHS
Grant: R01 MH101822
NHGRI NIH HHS
Grant: R21 HG007840
NIGMS NIH HHS
Grant: T32 GM007057
NHGRI NIH HHS
Grant: T32 HG003284
CCR NIH HHS
Grant: HHSN261200800001C
NHGRI NIH HHS
Grant: R00 HG006265
NIMH NIH HHS
Grant: R01 MH101820
NHGRI NIH HHS
Grant: T32 HG000044
NHGRI NIH HHS
Grant: U01 HG007900
Wellcome Trust
FWCI
366.82
Citation Percentile
1.0%
Citation Trend
Fields of Study
MeSH Terms
Keywords