Philip A. Cole

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

3in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 51 papers. Top paper: “Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours”.

Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours

Nature(2017)10.1038/nature24028

N/A

10.8DataRank · unranked

844 citations

Clarissa G. Jakob, Rohinton P. Edalji, Wei Qiu, Debra Montgomery, Enrico L. Digiammarino +34 more

The structural determinants of PH domain-mediated regulation of Akt revealed by segmental labeling

eLife(2020)10.7554/elife.59151

N/A

2.1DataRank · unranked

73 citations

Thibault Viennet, Hwan Bae, Antonieta L. Salguero, Andras Boeszoermenyi, Haribabu Arthanari +2 more

Diverse nucleosome Site-Selectivity among histone deacetylase complexes

eLife(2020)10.7554/elife.57663

N/A

1.8DataRank · unranked

80 citations

Christopher J. Millard, Chia‐Liang Lin, Jennifer E. Gurnett, Mingxuan Wu, Kwangwoon Lee +4 more

UM171 glues asymmetric CRL3–HDAC1/2 assembly to degrade CoREST corepressors

Nature(2025)10.1038/s41586-024-08532-4

N/A

1.4DataRank · unranked

49 citations

Olivia Zhang, Xiaowen Xie, Eunju Nam, N. Connor Payne, Pallavi M. Gosavi +27 more

The regulatory enzymes and protein substrates for the lysine β-hydroxybutyrylation pathway

Science Advances(2021)10.1126/sciadv.abe2771

N/A

0.814DataRank · unranked

227 citations

Di Zhang, Yejing Weng, Kyle Delaney, Zhanyun Tang, Cong Yan +6 more

Discovery of spirohydantoins as selective, orally bioavailable inhibitors of p300/CBP histone acetyltransferases

Bioorganic & Medicinal Chemistry Letters(2021)10.1016/j.bmcl.2021.127854

N/A

0.806DataRank · unranked

22 citations

Richard F. Clark, Vikram Bhat, T. Matthew Hansen, Loren M. Lasko, Kenneth D. Bromberg +13 more

Structural Basis of Sirtuin 6-Catalyzed Nucleosome Deacetylation

Journal of the American Chemical Society(2023)10.1021/jacs.2c13512

N/A

0.617DataRank · unranked

60 citations

Jonathan W. Markert, Samuel D. Whedon, Maheeshi Yapa Abeywardana, Kwangwoon Lee, Hanjie Jiang +5 more

Reference compounds for characterizing cellular injury in high-content cellular morphology assays

Nature Communications(2023)10.1038/s41467-023-36829-x

N/A

0.564DataRank · unranked

42 citations

Bruce K. Hua, Beth E. Zucconi, Shawn D. Nelson, Shantanu Singh, Anne E. Carpenter +21 more

KATs off: Biomedical insights from lysine acetyltransferase inhibitors

Current Opinion in Chemical Biology(2022)10.1016/j.cbpa.2022.102255

N/A

0.524DataRank · unranked

32 citations

Philip A. Cole, Samuel D. Whedon

PH domain-mediated autoinhibition and oncogenic activation of Akt

eLife(2022)10.7554/elife.80148

N/A

0.515DataRank · unranked

30 citations

Thibault Viennet, Eunyoung Park, Nam Chu, Antonieta L. Salguero, Michael J. Eck +3 more

Distinct biochemical properties of the class I histone deacetylase complexes

Current Opinion in Chemical Biology(2022)10.1016/j.cbpa.2022.102179

N/A

0.505DataRank · unranked

28 citations

Samuel D. Whedon, Zhipeng A. Wang, Philip A. Cole, Kwangwoon Lee

Multifaceted regulation of sirtuin 2 (Sirt2) deacetylase activity

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107722

N/A

0.406DataRank · unranked

14 citations

Samuel D. Whedon, Kwangwoon Lee, Eunju Nam, Rafael Dovarganes, Sarah DuBois-Coyne +4 more

Site‐Specific 5‐Formyl Cytosine Mediated DNA‐Histone Cross‐Links: Synthesis and Polymerase Bypass by Human DNA Polymerase η

Angewandte Chemie International Edition(2021)10.1002/anie.202109418

N/A

0.373DataRank · unranked

11 citations

Mingxuan Wu, Jenna Thomforde, Zhipeng A. Wang, Christopher Chao, Noelle M. Olson +5 more

A Small-Molecule Inhibitor of Gut Bacterial Urease Protects the Host from Liver Injury

ACS Chemical Biology(2025)10.1021/acschembio.3c00556

N/A

0.292DataRank · unranked

6 citations

Yindi Jiang, Vladimir Yeliseyev, Yancong Zhang, Eric A. Franzosa, Zhipeng A. Wang +6 more

Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes

Wellcome Open Research(2023)10.12688/wellcomeopenres.18826.1

N/A

0.274DataRank · unranked

4 citations

Cassandra A. Celatka, Hugh Young Rienhoff, Jay H. Kalin, Philip A. Cole, Damien Lassalle +6 more

The Allosteric Regulator Inositol Phosphate Dramatically Affects the Efficacy and Selectivity of Inhibitors for Different HDAC Complexes

Journal of the American Chemical Society(2025)10.1021/jacs.5c08929

N/A

0.269DataRank · unranked

5 citations

Urvashi Patel, Joshua P. Smalley, Christopher J. Millard, Edward A. Brown, Aline Renata Pavan +7 more

The CoREST Repressor Complex Mediates Phenotype Switching and Therapy Resistance in Melanoma

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.30.320580

N/A

0.208DataRank · unranked

3 citations

Ailish Hanly, Frederick Gibson, Kevin Kuang, Jay H. Kalin, Sarah E. Nocco +8 more

Reference compounds for characterizing cellular injury in high-content cellular morphology assays

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.12.499781

N/A

0.104DataRank · unranked

1 citations

Bruce K. Hua, Beth E. Zucconi, Shawn D. Nelson, Shantanu Singh, Anne E. Carpenter +21 more

Deubiquitinase processing of a non-natural linkage of ubiquitinated-PTEN

Bioorganic Chemistry(2025)10.1016/j.bioorg.2025.108223

N/A

0.104DataRank · unranked

1 citations

Isabella Jaen Maisonet, Kwangwoon Lee, Sara J. Buhrlage, Philip A. Cole, Reina Iwase

PH Domain-Mediated Autoinhibition and Oncogenic Activation of Akt

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.25.493453

N/A

0.104DataRank · unranked

1 citations

Thibault Viennet, Eunyoung Park, Nam Chu, Antonieta L. Salguero, Michael J. Eck +3 more

AANAT kinetics of CoASH-targeted electrophiles of tryptamine and related analogs

Bioorganic & Medicinal Chemistry Letters(2024)10.1016/j.bmcl.2024.129975

N/A

0.104DataRank · unranked

1 citations

Luke J. Hamilton, Jake Boley, Alexis Haynes, Makenna Redinger, Mackinzi Hill +5 more

The CoREST complex inhibitor, corin, leads to decreased tumor growth, increased cellular differentiation and extended lifespan in atypical teratoid rhabdoid tumor xenograft models

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.14.628381

N/A

0.104DataRank · unranked

1 citations

Nikhil Vaidya, Robert Fisher, Tyler Findlay, Yiming Deng, Khoa Pham +11 more

Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) is a druggable target involved in parasite survival, oviposition and stem cell proliferation

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.17.301184

N/A

0.104DataRank · unranked

1 citations

Cassandra A. Celatka, Hugh Young Rienhoff, Jay H. Kalin, Philip A. Cole, Damien Lassalle +5 more

Dynamic regulation of inter-organelle communication by ubiquitylation controls skeletal muscle development and disease onset

eLife(2023)10.7554/elife.81966

N/A

0DataRank · unranked

16 citations

Remi Joseph, Euri S Kim, Pierre M. Jean Beltran, Namrata D. Udeshi, Cadence Pearce +13 more

Inhibition of the CoREST Repressor Complex Promotes Wound Re-Epithelialization through the Regulation of Keratinocyte Migration

Journal of Investigative Dermatology(2023)10.1016/j.jid.2023.07.022

N/A

0DataRank · unranked

9 citations

Iqra Fatima, Elena Rozhkova, Marta Otero-Viñas, Muzhou Wu, Jay H. Kalin +5 more

Evaluation of Rhodanine Indolinones as AANAT Inhibitors

ChemMedChem(2023)10.1002/cmdc.202300567

N/A

0DataRank · unranked

7 citations

Luke J. Hamilton, Nicole Wandrey, Mackinzi Hill, Emery Mounce, Noah Mosel +11 more

The C-Terminal of NaV1.7 Is Ubiquitinated by NEDD4L

ACS Bio & Med Chem Au(2023)10.1021/acsbiomedchemau.3c00031

N/A

0DataRank · unranked

3 citations

Hanjie Jiang, Wendy Xia, Michael Murphy, Tatiana Boronina, Justin N. Nwafor +7 more

Nuclear GTPSCS functions as a lactyl-CoA synthetase to promote histone lactylation and gliomagenesis

Cell Metabolism(2024)10.1016/j.cmet.2024.11.005

N/A

0DataRank · unranked

177 citations

Xuelian Ren, Yae Eun Park, Huixu Feng, Xinlei Sheng, Xiaohan Song +13 more

Targeting lysine acetylation readers and writers

Nature Reviews Drug Discovery(2024)10.1038/s41573-024-01080-6

N/A

0DataRank · unranked

49 citations

Philip A. Cole, Ming‐Ming Zhou

An autoinhibitory switch of the LSD1 disordered region controls enhancer silencing

Molecular Cell(2024)10.1016/j.molcel.2024.05.017

N/A

0DataRank · unranked

18 citations

Hui Si Kwok, Ceejay Lee, Domenic N. Narducci, Allyson M. Freedy, Cindy Su +13 more

The CoREST repressor complex mediates phenotype switching and therapy resistance in melanoma

Journal of Clinical Investigation(2024)10.1172/jci171063

N/A

0DataRank · unranked

17 citations

Ailish Hanly, Frederick Gibson, Robert Fisher, Samantha Rogers, Kihyun Park +13 more

A MOZ-TIF2 leukemia mouse model displays KAT6-dependent H3K23 propionylation and overexpression of a set of active developmental genes

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2405905121

N/A

0DataRank · unranked

14 citations

Daniel Sullivan, Sarah Naomi Olsen, Heather A. Kang, Samuel D. Whedon, Jonathan B. Baell +4 more

Selective protein N-terminal labeling with N-hydroxysuccinimide esters

Methods in enzymology on CD-ROM/Methods in enzymology(2020)10.1016/bs.mie.2020.04.018

N/A

0DataRank · unranked

33 citations

Gabriel D. D’Agostino, Philip A. Cole, Daniel R. Dempsey, Hanjie Jiang

NEDD4L intramolecular interactions regulate its auto and substrate NaV1.5 ubiquitination

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.105715

N/A

0DataRank · unranked

11 citations

Sara Nathan, Hanjie Jiang, Wendy Xia, H Kim, Nourdine Chakouri +12 more

Protein semisynthesis reveals plasticity in HECT E3 ubiquitin ligase mechanisms

Nature Chemistry(2024)10.1038/s41557-024-01576-z

N/A

0DataRank · unranked

11 citations

Bryant D. Miller, Thibault Viennet, H Kim, Kwangwoon Lee, Haribabu Arthanari +2 more

Structural requirements for activity of Mind bomb1 in Notch signaling

Structure(2024)10.1016/j.str.2024.07.011

N/A

0DataRank · unranked

9 citations

Oren Gozlan, Alina Airich, Lena Tveriakhina, Haixia Zhou, Hanjie Jiang +6 more

p300 KAT Regulates SOX10 Stability and Function in Human Melanoma

Cancer Research Communications(2024)10.1158/2767-9764.crc-24-0124

N/A

0DataRank · unranked

8 citations

Nicole Grbic, Kassidy Leibowitz, William Austin Wyant, Sabah Choudhury, Kihyun Park +4 more

p300 KAT regulates SOX10 stability and function in human melanoma

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.20.581224

N/A

0DataRank · unranked

0 citations

Nicole Grbic, Kassidy Leibowitz, William Austin Wyant, Sabah Choudhury, Kihyun Park +4 more

A circular engineered sortase for interrogating histone H3 in chromatin

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.10.612318

N/A

0DataRank · unranked

0 citations

Kwangwoon Lee, Zhipeng A. Wang, Emily Zahn, Congcong Lu, Maheeshi Yapa-Abeywardana +15 more

Inhibiting the coregulator CoREST impairs Foxp3+ Treg function and promotes antitumor immunity

Journal of Clinical Investigation(2020)10.1172/jci131375

N/A

0DataRank · unranked

72 citations

Liqing Wang, Eros Di Giorgio, Tatiana Akimova, Ulf H. Beier, Rongxiang Han +5 more

Biochemical analysis of PD-L1 ubiquitination by CRL3SPOP, ARIH1, and NEDD4 family ubiquitin ligases

Structure(2025)10.1016/j.str.2025.05.005

N/A

0DataRank · unranked

2 citations

Lin Gao, Ruifang Lu, Linxia Tian, Tiantian Zheng, Xinning Li +6 more

Balancing Activation and Repression: CoREST-p300 Antagonism Controls Retinoic Acid-Driven Differentiation in AML

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.13.682235

N/A

0DataRank · unranked

0 citations

Helena G. Dos Santos, Sadat Dokaneheifard, Samuel D. Whedon, M. Valencia-S., Arigela Harikumar +5 more

Hydantion indolinones as AANAT inhibitors

Bioorganic & Medicinal Chemistry Letters(2025)10.1016/j.bmcl.2025.130459

N/A

0DataRank · unranked

0 citations

Jake Boley, Dirce Gómez-Galicia, Mackinzi Hill, Mason Bach, Sidney Gawrych +5 more

Site‐Specific 5‐Formyl Cytosine Mediated DNA‐Histone Cross‐Links: Synthesis and Polymerase Bypass by Human DNA Polymerase η

Angewandte Chemie(2021)10.1002/ange.202109418

N/A

0DataRank · unranked

3 citations

Mingxuan Wu, Jenna Thomforde, Zhipeng A. Wang, Christopher Chao, Noelle M. Olson +5 more

Mechanism of Crosstalk between the LSD1 Demethylase and HDAC1 Deacetylase in the CoREST Complex

Cell Reports(2020)10.1016/j.celrep.2020.01.091

N/A

0DataRank · unranked

142 citations

Lisbeth Dagil, Louise Fairall, Naomi Robertson, Mingxuan Wu, Timothy J. Ragan +9 more

p300 suppresses the transition of myelodysplastic syndromes to acute myeloid leukemia

JCI Insight(2021)10.1172/jci.insight.138478

N/A

0DataRank · unranked

19 citations

Glòria Mas Martín, Daniel Karl, Jun Sun, Fan Liu, Qin Yang +16 more

N‐Terminal Protein Labeling with N‐Hydroxysuccinimide Esters and Microscale Thermophoresis Measurements of Protein‐Protein Interactions Using Labeled Protein

Current Protocols(2021)10.1002/cpz1.14

N/A

0DataRank · unranked

23 citations

Philip A. Cole, Hanjie Jiang

HDAC2 targeting stabilizes the CoREST complex in renal tubular cells and protects against renal ischemia/reperfusion injury

Scientific Reports(2021)10.1038/s41598-021-88242-3

N/A

0DataRank · unranked

28 citations

Paul T. Hernandez, Seth J. Concors, Ciaran O’Brien, Zhong Lin Wang, Douglas R. Murken +15 more

Enzymatic analysis of WWP2 E3 ubiquitin ligase using protein microarrays identifies autophagy-related substrates

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.101854

N/A

0DataRank · unranked

18 citations

Claire Y Chiang, Zan Chen, Sara Nathan, Gabriel D. D’Agostino, Joao A. Paulo +5 more

Dynamic regulation of inter-organelle communication by ubiquitylation controls skeletal muscle development and disease onset

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.21.501000

N/A

0DataRank · unranked

0 citations

Remi Joseph, Pierre Michael Jean-Beltran, Namrata D. Udeshi, Cadence Pearce, Hanjie Jiang +9 more

A central role for regulated protein stability in the control of TFE3 and MITF by nutrients

Molecular Cell(2023)10.1016/j.molcel.2022.12.013

N/A

0DataRank · unranked

50 citations

Brad A. Palanski, Daniel C. Scott, Richard T. Timms, Karl W. Barber, Xin Gu +7 more