Charles S. Craik

Also affiliated with Quantitative BioSciences

Biochemistry, Genetics and Molecular BiologyMedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 53 papers. Top paper: “A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing”.

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.22.002386

N/A

14.3DataRank · unranked

456 citations

Gwendolyn M. Jang, Mehdi Bouhaddou, Jiewei Xu, Kirsten Obernier, Matthew J. O’Meara +95 more

Mapping the catalytic conformations of an assembly-line polyketide synthase module

Science(2021)10.1126/science.abi8358

N/A

2.3DataRank · unranked

87 citations

Kaiming Zhang, Xiuyuan Li, Shanshan Li, Grigore Pintilie, Soung‐Hun Roh +4 more

A covalent inhibitor of K-Ras(G12C) induces MHC class I presentation of haptenated peptide neoepitopes targetable by immunotherapy

Cancer Cell(2022)10.1016/j.ccell.2022.07.005

N/A

0.735DataRank · unranked

133 citations

Peter J. Rohweder, Chayanid Ongpipattanakul, Koli Basu, Markus‐Frederik Bohn, Eli Dugan +5 more

Phosphorylation of tau at a single residue inhibits binding to the E3 ubiquitin ligase, CHIP

Nature Communications(2024)10.1038/s41467-024-52075-1

N/A

0.713DataRank · unranked

28 citations

Saugat Pokhrel, Kristin Wucherer, Abby Oehler, Aye C. Thwin, Koli Basu +6 more

Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients

eLife(2020)10.7554/elife.62611

N/A

0.678DataRank · unranked

91 citations

Bastian Bräuning, Katerina D. Popova, Nicole T Schirle Oakdale, Jessica L. Bonnar, J. Rajan Prabu +9 more

Structure-function analysis of enterovirus protease 2A in complex with its essential host factor SETD3

Nature Communications(2022)10.1038/s41467-022-32758-3

N/A

0.612DataRank · unranked

9 citations

Ursula Schulze‐Gahmen, Manon Eckhardt, Gwendolyn M. Jang, Jiewei Xu, Ernst H. Pulido +9 more

Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.0c02177

N/A

0.515DataRank · unranked

30 citations

Pavel Šácha, Jana Starková, J. Brynda, Martin Hradílek, Eva Tloušťová +11 more

Rare antibody phage isolation and discrimination (RAPID) biopanning enables identification of high-affinity antibodies against challenging targets

Communications Biology(2023)10.1038/s42003-023-05390-0

N/A

0.360DataRank · unranked

10 citations

Sophie Kong, Nicholas J. Young, Shih‐Wei Chuo, Jamie V. Shiah, Emily J. Connelly +7 more

Large library docking for novel SARS-CoV-2 main protease non-covalent and covalent inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.05.498881

N/A

0.360DataRank · unranked

10 citations

Conner Bardine, Stefan Gahbauer, Isha Singh, Kris M. White, Shuo Gu +19 more

Therapeutic Targeting and Structural Characterization of a Sotorasib-Modified KRAS G12C–MHC I Complex Demonstrate the Antitumor Efficacy of Hapten-Based Strategies

Cancer Research(2024)10.1158/0008-5472.can-24-2450

N/A

0.345DataRank · unranked

9 citations

Peter J. Rohweder, Lieza M. Chan, Chayanid Ongpipattanakul, Dong hee Chung, Bryce Paolella +6 more

Isoforms of Cathepsin B1 in Neurotropic Schistosomula of Trichobilharzia regenti Differ in Substrate Preferences and a Highly Expressed Catalytically Inactive Paralog Binds Cystatin

Frontiers in Cellular and Infection Microbiology(2020)10.3389/fcimb.2020.00066

N/A

0.241DataRank · unranked

4 citations

Roman Leontovyč, Tomáš Macháček, Anthony J. O’Donoghue, Ondřej Šedo, Zbyněk Zdráhal +5 more

Structure of an affinity-matured inhibitory recombinant fab against urokinase plasminogen activator reveals basis of potency and specificity

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics(2020)10.1016/j.bbapap.2020.140562

N/A

0.241DataRank · unranked

4 citations

Markus‐Frederik Bohn, Marcell Zimanyi, Y. Chen, Christopher J. Petzold, Sayan Gupta +3 more

Imaging the Granzyme Mediated Host Immune Response to Viral and Bacterial Pathogens In Vivo Using Positron Emission Tomography

ACS Infectious Diseases(2024)10.1021/acsinfecdis.4c00114

N/A

0.241DataRank · unranked

4 citations

Shalini Chopra, Simon J. Cleary, Marina López‐Álvarez, Fiona M. Quimby, Aryn A. Alanizi +7 more

On-Resin Assembly of Macrocyclic Inhibitors of Cryptococcus neoformans May1: A Pathway to Potent Antifungal Agents

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c00396

N/A

0.208DataRank · unranked

3 citations

Václav Verner, Pavel Šácha, Martin Hadzima, Filip Trajhan, Jana Starková +13 more

Identification of recombinant Fabs for structural and functional characterization of HIV-host factor complexes

PLoS ONE(2021)10.1371/journal.pone.0250318

N/A

0.165DataRank · unranked

2 citations

Evan M. Green, Jörg Votteler, Dong Young Kim, Xuefeng Ren, Bei Yang +8 more

Immunotargeting of Nanocrystals by SpyCatcher Conjugation of Engineered Antibodies

ChemRxiv(2021)10.26434/chemrxiv-2021-9q5xr

N/A

0.104DataRank · unranked

1 citations

Victor R. Mann, Kathrin Zuberbühler, Markus‐Frederik Bohn, Jessica Yu, Virginia Altoé +3 more

Accurate Identification of Mucinous Pancreatic Cystic Lesions Using Small-Volume Analytes

Journal of Surgical Research(2022)10.1016/j.jss.2022.08.014

N/A

0.104DataRank · unranked

1 citations

Patricia C. Conroy, Sam L. Ivry, Tyler York, Joseph Lin, Sophia Hernandez +9 more

Combination of antifungal drugs and protease inhibitors prevent Candida albicans biofilm formation and disrupt mature biofilms

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.02.11.945030

N/A

0DataRank · unranked

0 citations

Megha Gulati, Charles S. Craik, Alexander D. Johnson, Clarissa J. Nobile, Matthew B. Lohse

Global Protease Activity Profiling Identifies HER2-Driven Proteolysis in Breast Cancer

ACS Chemical Biology(2021)10.1021/acschembio.0c01000

N/A

0DataRank · unranked

11 citations

Michael B. Winter, Natalia Khuri, Giselle M. Knudsen, Andrej Săli, Charles S. Craik +1 more

Colloidal aggregators in biochemical SARS-CoV-2 repurposing screens

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.31.458413

N/A

0DataRank · unranked

5 citations

Tia A. Tummino, Conner Bardine, Charles S. Craik, Brian K. Shoichet, Henry O’Donnell

Immunotargeting of Nanocrystals by SpyCatcher Conjugation of Engineered Antibodies

Figshare(2021)10.33774/chemrxiv-2021-9q5xr

N/A

0DataRank · unranked

2 citations

Victor R. Mann, Kathrin Zuberbühler, Markus‐Frederik Bohn, Jessica Yu, Virginia Altoé +3 more

An opaque cell-specific expression program of secreted proteases and transporters allows cell-type cooperation in Candida albicans

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.21.053991

N/A

0DataRank · unranked

1 citations

Lucas R. Brenes, Naomi Ziv, Michael B. Winter, Charles S. Craik, Alexander D. Johnson +1 more

Platform to Discover Protease-Activated Antibiotics and Application to Siderophore-Antibiotic Conjugates

ChemRxiv(2020)10.26434/chemrxiv.12809603

N/A

0DataRank · unranked

2 citations

Bobo Dang, Beatrice Ary, Quinn Edmondson, Charles S. Craik, William F. DeGrado +2 more

Inhibiting a dynamic viral protease by targeting a non-catalytic cysteine

Cell chemical biology(2022)10.1016/j.chembiol.2022.03.007

N/A

0DataRank · unranked

12 citations

Priyadarshini Jaishankar, Gregory M. Lee, Markus‐Frederik Bohn, Emily J. Connelly, Kristin Wucherer +7 more

Translation of a Protease Turnover Assay for Clinical Discrimination of Mucinous Pancreatic Cysts

Diagnostics(2022)10.3390/diagnostics12061343

N/A

0DataRank · unranked

5 citations

Kaleb Byers, U. Chinna Rajesh, Francesco Caiazza, Gina Zhu, Charles S. Craik +4 more

Platform to Discover Protease-Activated Antibiotics and Application to Siderophore-Antibiotic Conjugates

ChemRxiv(2020)10.26434/chemrxiv.12809603.v2

N/A

0DataRank · unranked

3 citations

Bobo Dang, Beatrice Ary, Quinn Edmondson, Charles S. Craik, William F. DeGrado +2 more

Structural Basis of Prostaglandin Efflux by MRP4

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.22.521501

N/A

0DataRank · unranked

2 citations

Evan Green, Ruchika Bajaj, Ilan E. Chemmama, Giselle M. Knudsen, Meghna Gupta +6 more

Large library docking for novel SARS‐CoV ‐2 main protease non‐covalent and covalent inhibitors

Protein Science(2023)10.1002/pro.4712

N/A

0DataRank · unranked

43 citations

Conner Bardine, Stefan Gahbauer, Isha Singh, Tyler C. Detomasi, Kris M. White +26 more

Mutations in α-synuclein, TDP-43 and tau prolong protein half-life through diminished degradation by lysosomal proteases

Molecular Neurodegeneration(2023)10.1186/s13024-023-00621-8

N/A

0DataRank · unranked

38 citations

Shruti Arya, Giselle M. Knudsen, Emma L. Gunderson, Angélica Sandoval‐Pérez, Molly Hodul +5 more

The E3 Ubiquitin Ligase, CHIP/STUB1, Inhibits Aggregation of Phosphorylated Proteoforms of Microtubule-associated Protein Tau (MAPT)

Journal of Molecular Biology(2023)10.1016/j.jmb.2023.168026

N/A

0DataRank · unranked

34 citations

Aye C. Thwin, Matthew Callahan, Kanghyun Lee, Emily J. Connelly, Charles S. Craik +3 more

Perturbations in podocyte transcriptome and biological pathways induced by FSGS associated circulating factors

Annals of Translational Medicine(2023)10.21037/atm-22-3670

N/A

0DataRank · unranked

10 citations

Tara K. Sigdel, Dmitry Rychkov, Izabella Damm, Andrea Alice Da Silva, Flavio Vincenti +5 more

Bivalent binding of a fully human IgG to the SARS-CoV-2 spike proteins reveals mechanisms of potent neutralization

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.14.203414

N/A

0DataRank · unranked

24 citations

Daniel Asarnow, Wen-Hsin Sandy Lee, Ching-Wen Huang, Bryan Faust, Patricia Miang Lon Ng +22 more

Discovery and Characterization of Antibody Probes of Module 2 of the 6-Deoxyerythronolide B Synthase

Biochemistry(2023)10.1021/acs.biochem.3c00156

N/A

0DataRank · unranked

5 citations

D.P. Cogan, Krystal L. Brodsky, Alexander M. Soohoo, Xiuyuan Li, Natalia Sevillano +5 more

Addressing the unmet clinical need for low-volume assays in early diagnosis of pancreatic cancer

Frontiers in Gastroenterology(2023)10.3389/fgstr.2023.1258998

N/A

0DataRank · unranked

1 citations

Kaleb Byers, Mini Thomas, U. Chinna Rajesh, Kelli Ann Ifuku, Kimberly S. Kirkwood +4 more

A Prototype Assay Multiplexing SARS-CoV-2 3CL-Protease and Angiotensin-Converting Enzyme 2 for Saliva-Based Diagnostics in COVID-19

Biosensors(2023)10.3390/bios13070682

N/A

0DataRank · unranked

3 citations

Daniel A. Sheik, Tyler C. Detomasi, Tianqi Zhao, Theresa Zepeda, Shyam M. Saladi +5 more

Preparing for the next pandemic

Science(2023)10.1126/science.adk5868

N/A

0DataRank · unranked

13 citations

Charles S. Craik, Brian K. Shoichet

Phosphorylation of a Cleaved Tau Proteoform at a Single Residue Inhibits Binding to the E3 Ubiquitin Ligase, CHIP

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.16.553575

N/A

0DataRank · unranked

1 citations

Kristin Wucherer, Abby Oehler, Aye C. Thwin, Koli Basu, Matthew Callahan +5 more

Monitoring protease activity in biological tissues using antibody prodrugs as sensing probes

Scientific Reports(2020)10.1038/s41598-020-62339-7

N/A

0DataRank · unranked

34 citations

Elizabeth Menendez, Margaret Nguyen, Charles S. Craik, W. Michael Kavanaugh, Olga Vasiljeva

Structural basis of prostaglandin efflux by MRP4

Nature Structural & Molecular Biology(2024)10.1038/s41594-023-01176-4

N/A

0DataRank · unranked

25 citations

Evan Green, Ruchika Bajaj, Ilan E. Chemmama, Giselle M. Knudsen, Meghna Gupta +6 more

An Opaque Cell-Specific Expression Program of Secreted Proteases and Transporters Allows Cell-Type Cooperation in Candida albicans

Genetics(2020)10.1534/genetics.120.303613

N/A

0DataRank · unranked

8 citations

Lucas R. Brenes, Naomi Ziv, Michael B. Winter, Charles S. Craik, Alexander D. Johnson +1 more

Antibody Probes of Module 1 of the 6-Deoxyerythronolide B Synthase Reveal an Extended Conformation During Ketoreduction

Journal of the American Chemical Society(2020)10.1021/jacs.0c05133

N/A

0DataRank · unranked

11 citations

Xiuyuan Li, Natalia Sevillano, Irimpan I. Mathews, Tsutomu Matsui, Charles S. Craik +2 more

Large library docking and biophysical analysis of small molecule TMPRSS2 inhibitors

ChemRxiv(2024)10.26434/chemrxiv-2024-v1sc1

N/A

0DataRank · unranked

1 citations

Nicholas Young, Brian J. Bender, Stefan Gahbauer, Olzhas Ilyassov, R Wilson +10 more

Identifying protease-activated targets and exploring therapeutic applications

Expert Opinion on Therapeutic Targets(2025)10.1080/14728222.2025.2563244

N/A

0DataRank · unranked

5 citations

Charles S. Craik, Deokhee Kang

Combination of Antifungal Drugs and Protease Inhibitors Prevent Candida albicans Biofilm Formation and Disrupt Mature Biofilms

Frontiers in Microbiology(2020)10.3389/fmicb.2020.01027

N/A

0DataRank · unranked

65 citations

Megha Gulati, Charles S. Craik, Alexander D. Johnson, Clarissa J. Nobile, Matthew B. Lohse

Large Library Docking and Biophysical Analysis of Small-Molecule TMPRSS2 Inhibitors

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.4c03089

N/A

0DataRank · unranked

2 citations

Nicholas J. Young, Brian J. Bender, Stefan Gahbauer, Olzhas Ilyassov, Ryan P. Wilson +10 more

Recombinant antibodies inhibit enzymatic activity of the E3 ubiquitin ligase CHIP via multiple mechanisms

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.108220

N/A

0DataRank · unranked

2 citations

Emily J. Connelly, Aparna Unnikrishnan, Shih‐Wei Chuo, Kristin Wucherer, Cory M. Nadel +4 more

Antibody Reveals Conformational Latch Controlling Herpesvirus Proteases

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.17.683123

N/A

0DataRank · unranked

1 citations

Kaitlin R. Hulce, Markus‐Frederik Bohn, Jordan Norman, Peter J. Rohweder, Yifan Cheng +2 more

Precision Labeling of Native Antibodies with Lock Coupling

ChemRxiv(2025)10.26434/chemrxiv-2025-1hmzh

N/A

0DataRank · unranked

0 citations

Isha Nadig, Abijeet Mehta, Shih‐Wei Chuo, Yee-Kin Ho, James Tyler +4 more

96 Real-time in vivo imaging of therapeutic biodistribution with a miniaturized, implantable fluorescence imager

Regular and Young Investigator Award Abstracts(2025)10.1136/jitc-2025-sitc2025.0096

N/A

0DataRank · unranked

0 citations

Abijeet Mehta, Jack Bartley, Rozhan Rabbani, Longhui Qiu, Hui Zhang +6 more

A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2108728118

N/A

0DataRank · unranked

120 citations

Vishnu C. Damalanka, Michael A. Tartell, Dong hee Chung, André Luiz Lourenço, Dustin Pwee +18 more

Precision Labeling of Native Antibodies with Lock Coupling

ChemRxiv(2025)10.26434/chemrxiv-2025-1hmzh-v2

N/A

0DataRank · unranked

0 citations

Isha Nadig, Abijeet Mehta, Shih‐Wei Chuo, Yee-Kin Ho, James Tyler +4 more

Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia

Cell(2021)10.1016/j.cell.2021.04.033

N/A

0DataRank · unranked

83 citations

Bei Wang, Wen-Hsin Sandy Lee, Yuanyu Hu, Ching-Wen Huang, Bryan Faust +26 more

In Vivo Measurement of Granzyme Proteolysis from Activated Immune Cells with PET

ACS Central Science(2021)10.1021/acscentsci.1c00529

N/A

0DataRank · unranked

64 citations

Conner Bardine, André Luiz Lourenço, Yung-Hua Wang, Yangjie Huang, Simon J. Cleary +7 more